Abstract. Large language models (LLMs) have made excellent progress in text and image understanding and generation. However, with the wide range of applications of these models in various industries, the issue of their security, especially the defense against adversarial attacks, has become a focus of research. This study focuses on exploring the adversarial attacks faced by LLMs and their defense strategies, especially the design and optimization of defense mechanisms. Through literature review and case studies, this paper analyzes in detail the white-box and black-box attack patterns against LLMs, including model inversion, backdoor attacks, and token-based strategies. In response to these attacks, this paper proposes a series of defense strategies, including preventive measures such as data augmentation, adversarial training and model regularization, as well as real-time attack detection and response strategies such as anomaly detection and adversarial sample detection techniques. The core of this research is to improve the robustness and trustworthiness of LLMs, providing the necessary guarantees for their integration and sustainability in multiple industrial applications. In addition, this paper proposes future research directions, highlighting the importance of developing advanced defense systems, promoting interdisciplinary research and exploring new applications for LLMs. This research provides valuable insights into understanding and improving the security defense mechanisms of LLMs, which is essential for maintaining the security and user trust of these models.