To investigate ex vivo the influence of the post system on fracture resistance and failure mode of root filled incisor, canine, premolar and molar teeth. Eighty human teeth were divided into eight groups (n = 10) resulting from the interaction between the two study factors: post system (glass fibre post; cast Ni-Cr alloy post and core) and type of tooth (maxillary incisors, maxillary canines, maxillary premolars and mandibular molars). All roots were prepared with a 2-mm ferrule and restored with metal crown. Fracture resistance (N) was assessed in a mechanical testing device, and the data were analysed by two-way anova (4 × 2) followed by Tukey's test (α = 0.05). The failure mode was evaluated using an optical stereomicroscope and classified according to the location of the failure. Failure mode data were analysed by two-factor anova and Student-Newman-Keuls (SNK) tests (α = 0.05). Correlation between fracture resistance and failure mode was analysed by linear regression. Glass fibre and cast posts and cores had similar fracture resistance, regardless of the type of tooth. Canines and molars had significantly higher fracture resistance (P < 0.001) than premolars. Incisors teeth had significantly lower fracture resistance (P < 0.001) than premolars. The fracture mode for incisors, premolars and molars was more amenable to restoration when the teeth were restored with glass fibre posts. Fracture resistance had no correlation with fracture mode, regardless of the post system and type of tooth analysed. Post system had no significant effect on fracture resistance, regardless of the type of tooth. The mode of fracture was more restorable with glass fibre posts.