Step Forward Research Articles

Response to “Recent AADSM Protocol Update: A Step Forward, or Backward?”

Response to “Recent AADSM Protocol Update: A Step Forward, or Backward?”

Strategic Planning for Hospital Management Information System (SIMRS) Dental and Oral Hospital (RSGM) Universitas Andalas (Unand) Indonesia

In the current information era, hospitals, including dental and oral hospitals, are required to improve performance and competitiveness as a business entity by not reducing the mission it carries. Currently, computer-based management information systems are a very important supporting tool, and it could even be said to be absolutely necessary to support hospital operational management. A hospital management information system, hereinafter abbreviated as SIMRS, is a communication information technology system that processes and integrates the entire flow of hospital service processes in the form of a network of coordination, reporting, and administrative procedures to obtain precise and accurate information and is part of the health information system. Efforts to utilize information systems are a step forward that need to be implemented in the face of very rapid changes, and the impact of the era of globalization is starting to be felt. Having a health information system is very helpful in data processing activities, most of which are carried out using computers that have been programmed with various programs that will handle an application.

More Steps Forward for the Journal of Lower Genital Tract Disease.

More Steps Forward for the Journal of Lower Genital Tract Disease.

Understanding multimorbidity early in life takes a step forward

Understanding multimorbidity early in life takes a step forward

Generational Leap or Modest Step Forward? Non-Covalent Bruton Tyrosine Kinase Inhibition in Mantle Cell Lymphoma

Generational Leap or Modest Step Forward? Non-Covalent Bruton Tyrosine Kinase Inhibition in Mantle Cell Lymphoma

Technology Focus: Gas Production (August 2023)

The demand for natural gas remains unabated and with it the need to further develop and disseminate gas-production-related expertise. A few of the common themes that emerge from recent SPE publications are elaborated upon here. The recovery of condensate from gas condensate depletion drive reservoirs is much lower than the recovery of gas from the same reservoirs because of condensate dropping out below dewpoint pressure. Besides pressure maintenance, no field-proven methods are yet available to mobilize this trapped condensate. Most papers present model or laboratory results without mentioning field data. The same applies to inflow impairment because of condensate dropout; many modeling studies lack validation against field data. Case in point: Pressure/volume/temperature testing generally does not venture below 500–1,000 psi pressure while many reservoirs reach (near-wellbore) pressures well below that range. Reducing emissions of natural gas or CO2 has become a key deliverable of most projects. Some papers present dedicated technology, while many others emphasize emission reduction as an important side benefit. Artificial intelligence (AI) is permeating the exploration and production business, as it does society at large, and features in many recent papers. So far, most applications use advanced data analysis to achieve higher derived data accuracy. This appears to be very successful as long as the evaluated data is within the domain of the training data. It is not always clear how well the AI models perform outside of their training domain. A relevant question is whether complex AI techniques applicable within a restricted domain can or should be used to replace simple, well-established engineering relations. Time will tell how deep and wide AI will affect day-to-day gas production applications. Recommended additional reading at OnePetro: www.onepetro.org. SPE 210136 The Reversible Relationship Between Choke Management and Liquid Yield Trends in Shale Reservoirs by Yalda Barzin, Repsol, et al. SPE 210099 Innovative, Cost-Effective, and Zero-Flaring Solution to Clean Up and Start Up New Wells in a High-H2S Field in Kazakhstan— The Vital Step Forward Toward Net-Zero Carbon Footprint by Timur Tankiyev, Karachaganak Petroleum Operating, et al. SPE 209745 A Data-Driven Approach To Predict the Critical Gas Flow Rate in Gas Wells by Ehsan Rahmati, Ambyint, et al.

Towards semantic operationalisation of the business model: a step forward

PropósitoEste artigo tem como objetivo desenvolver um framework para a operacionalização semântica do modelo de negócio, que possibilita a identificação automatizada de modelos de negócio por meio de análise de conteúdo.Design/metodologia/abordagemAbordamos a operacionalização do modelo de negócio realizando uma revisão da literatura organizacional e de gestão para derivar os principais elementos do modelo de negócio destacados nas pesquisas existentes, juntamente com suas palavras-chave associadas.ResultadosNosso estudo propôs um framework conceitual que especifica uma estrutura granular de elementos do modelo de negócio, assim como as palavras-chave que caracterizam cada elemento. Ao descer ao nível de palavras-chave distintas, chegamos a construtos mensuráveis para capturar a magnitude de cada elemento no modelo de negócio de uma empresa.OriginalidadeNosso estudo é o primeiro a oferecer uma operacionalização semântica do modelo de negócio, definindo o conjunto de palavras-chave que se referem a cada elemento do modelo de negócio. A operacionalização proposta do modelo de negócio pode auxiliar pesquisas empíricas futuras, servindo como uma ferramenta para a avaliação automatizada da magnitude de cada elemento no modelo de negócio de uma empresa por meio de análise de conteúdo.

Innovative stem cell-based strategies for corneal wound healing: A step forward

Innovative stem cell-based strategies for corneal wound healing: A step forward

One Step Forward and Two Steps Back: The Role of Civil Society Organizations in Reversed Integration Processes among Refugees in Norway

One Step Forward and Two Steps Back: The Role of Civil Society Organizations in Reversed Integration Processes among Refugees in Norway

Taking School Instrumentation One Step Forward: A Do-It-Yourself Type Spectrophotometer and a Jupyter Notebook That Enable Real Time Spectroscopy during School Lessons

A major obstacle that teachers face when they begin their spectroscopy lessons is the lack of a spectrophotometer, mostly due to its relatively high cost. In the present study, the construction of a low-cost do-it-yourself type of instrument is reported. Its construction, as a part of a problem-based scenario, would also help students to enhance their chemical literacy. Moreover, the creation of a Jupyter Notebook called “Spectrophotometry” is also described. With this tool, students and teachers, within a few clicks, will derive absorption and fluorescence spectra and do kinetics studies without any difficulty and the need for time-consuming data postprocessing software. Finally, the views of a group of students on the construction and ease of use of our spectrophotometer are discussed in detail.

Private Madrasah Development Strategy at Madrasah Aliyah

This study aims to analyze the Private Madrasah Development Strategy at Madrasah Aliyah Al-Hilal Dobo Aru Islands, Maluku. Qualitative research with the type of case study, data sources from madrasa heads, teaching staff, heads of administration, heads of madrasah committees, writings, books, and documents related to the object under study. Collecting data through observation, interviews, and documentation. Data analysis utilizing data reduction, data presentation, and conclusion. Testing the validity of the data is done by extending observations, increasing persistence, and triangulation. The results of the study show that Madrasah Aliyah Al-Hilal Dobo Aru Islands Maluku has the motto One Step Forward. The strategy undertaken is to carry out planning by involving internal and external stakeholders, implementing the strategy by forming a team that is divided into several fields that are specifically tasked with being responsible for the process of implementing the programs that have been determined, then evaluated in three stages, namely short term, medium term, long-term. Efforts made include improving teachers' teaching abilities, optimizing the use of media and educational facilities, carrying out routine supervision, establishing cooperation with the community, and applying strict discipline.

Insights into Hemodynamic Features of Survivors and the Deceased with Acute Brain Injury: A Step Forward Tailored Treatment.

Pulmonary artery catheters are widely used for hemodynamical monitoring in critically ill patients. Acute brain injury is among the severe conditions treated in an intensive care unit. The advanced monitoring of hemodynamical parameters, fluid balance and adequate administered treatment based on those values are components of goal-directed therapy. A prospective observational study included adult patients who were hospitalized in the ICU due to acute bran injury, excluding brain oedema after cardiac arrest. Each patient had PAC inserted and hemodynamic data were collected during the first 3 days of the ICU stay every 6 h. Patients were divided into two groups based on the endpoint: the survivors and the deceased. Length of stay in hospital differed between patiens. All patients, regardless of their outcome, had noradrenaline administered. The initial values of PAP differed between the groups (p = 0.05). There were positive correlations noticed between noradrenaline dose, CVP and fluid balance when compared to PCWP in a group of survivors and a positive correlation in the fluid balance when compared to PAP and PVRI. Lactate serum concentrations presented a correlation with the dose of noradrenaline in both groups. Upon acute brain injury, values of PVRI and PAP increase. This is corelated with fluid load and worsened by an excessive fluid treatment in the case of an inconsiderate approach for stabilizing the patient hemodynamically. PAC may present limited advantages in terms of PAP and PVRI control during the treatment.

AI to the rescue of voltage imaging

In a recent issue of Nature Methods, Platisa etal. present an approach for long-term, invivo population voltage imaging with single spike resolution across a local population of 100 neurons.1 Key to this step forward was the combination of a customized high-speed two-photon microscope with an optimized, positive-going, genetically encoded voltage indicator and a tailored machine learning denoising algorithm.

Deep Mobile Path Prediction With Shift-and-Join and Carry-Ahead

Importance of user mobility has rapidly increased in 5G due to reduced cell sizes, management of Multi-access Edge Computing (MEC), and ultra-low latency services. Reactive nature of existing management systems is a bottleneck, and it can be solved by building proactive systems that exploit temporal characteristics of time-series mobility data to predict long-term user movement (i.e.path). However, user mobile path prediction with useable accuracy is a challenging task, particularly for lengthy target trajectories. This paper adopts general approaches to propose two models for predicting mobile path with high accuracy. Step Forward Iteration (SFI) model is based on recursive approach, whereas Encoder-Decoder (ED) model follows multi-output approach, and both the models use Long-Short Term Memory (LSTM) as the learning unit. Training and testing of these models is done on mobility datasets from the wireless network of Pangyo ICT Research Center, Korea and one of the Korean mobile operators. The experiment results show viability of the proposed models for leveraging mobile network management, as they outperform state-of-the-art GRU with attention (GRU-ATTN) and Transformer Network (TN) models. The highest prediction accuracies achieved for 3, 5, and 7 steps of target sequences (i.e.predicted mobile path) in the campus dataset are 96%, 90%, and 87%, respectively.

A Step Forward to Harmonise Wireless Charging after the European Law on a Single Standard for Charging Devices

A Step Forward to Harmonise Wireless Charging after the European Law on a Single Standard for Charging Devices

High sensitivity and wide response range artificial synapse based on polyimide with embedded graphene quantum dots

Artificial electronic synapses are commonly used to simulate biological synapses to realize various learning functions, regarded as one of the key technologies in the next generation of neurological computation. This work used a simple spin coating technique to fabricate polyimide (PI):graphene quantum dots(GQDs) memristor structure. As a result, the devices exhibit remarkably stable exponentially decaying postsynaptic suppression current over time, as interpreted in the spike-timing-dependent plasticity phenomenon. Furthermore, with the increase of the applied electrical signal over time, the conductance of the electrical synapse gradually changes, and the electronic synapse also shows plasticity dependence on the amplitude and frequency of the pulse applied. In particular, the devices with the structure of Ag/PI:GQDs/ITO prepared in this study can produce a stable response to the stimulation of electrical signals between millivolt to volt, showing not only high sensitivity but also a wide range of “feelings”, which makes the electronic synapses take a step forwards to emulate biological synapses. Meanwhile, the electronic conduction mechanisms of the device are also studied and expounded in detail. The findings in this work lay a foundation for developing brain-like neuromorphic modeling in artificial intelligence.

Gene transfer in hemophilia B: a big step forward

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Research and practice of blaze new trails and start an undertaking cultivate model based on big data technology in computer special field of study

Abstract With the advent of the era of big data and cloud computing, big data is more and more widely used in various industries, and the research and practice of using big data technology to realize blaze new trails and start an undertaking cultivate mode in computer special field of study will become an important focus of the blaze new trails and start an undertaking cultivate system nowadays. In this paper, we construct the blaze new trails and start an undertaking cultivate model based on BP ANN, construct the blaze new trails and start an undertaking cultivate evaluation index system through Delphi method, and finally design the model of blaze new trails and start an undertaking cultivate evaluation in order to analyze the results of blaze new trails and start an undertaking cultivate. The scoring results correspond to the data of 21 evaluation indexes of a student, and the various scores can map to the level of individual students’ blaze new trails and start an undertaking ability, and provide effective countermeasures for computer special field of study students’ blaze new trails and start an undertaking cultivate. This paper effectively evaluates the blaze new trails and start an undertaking ability of students, broadens the application value and research field of BP ANN, and actively explores the blaze new trails and start an undertaking cultivate of computer special field of study students, which helps the operation mode of blaze new trails and start an undertaking cultivate of computer special field of study special field of study, provides step foreward ideas, and is of great significance to promote the step forward of blaze new trails and start an undertaking cultivate mode.

Stepping Back to Step Forward: Reflection in a Community of Practice

Click to increase image sizeClick to decrease image size Additional informationNotes on contributorsCarrie Y. NordlundCarrie Y. Nordlund, Professor, Department of Art Education, Kutztown University of Pennsylvania in Kutztown. Email: Nordlund@kutztown.eduJulia L. HovanecJulia L. Hovanec, Associate Professor, Department of Art Education, Kutztown University of Pennsylvania in Kutztown. Email: Hovanec@kutztown.eduNotes1 https://abcnews.go.com/GMA/video/gma-viewers-share-inspires-words-45182145.

Harnessing mitochondrial transplantation to sustain cardiac function: Another step forward

The mitochondria, apart from balancing optimal cellular homeostasis and energetics to sustain life, also mediate pathophysiological mechanisms leading to injury and death. In this regard, mitochondrial transplantation is emerging as a novel therapeutic strategy to circumvent deleterious effects of mitochondrial dysfunction in various pathological disorders. The transplantation of mitochondria involves the process of isolation, selection of optimal mitochondria, transfer, and internalization of exogenous intact mitochondria into the target cells or tissue. In the myocardium, metabolic and ionic changes secondary to the lack of oxygen are major contributors to mitochondrial damage. Mitochondrial transplantation has been demonstrated to protect against cardiac ischemia-reperfusion injury 1 Masuzawa A. Black K.M. Pacak C.A. Ericsson M. Barnett R.J. Drumm C. Seth P. Bloch D.B. Levitsky S. Cowan D.B. McCully J.D. Transplantation of autologously derived mitochondria protects the heart from ischemia-reperfusion injury. Am. J. Physiol. Heart Circ. Physiol. 2013; 304: H966-H982https://doi.org/10.1152/AJPHEART.00883.2012 Crossref PubMed Scopus (0) Google Scholar ,2 Cowan D.B. Yao R. Akurathi V. Snay E.R. Thedsanamoorthy J.K. Zurakowski D. Ericsson M. Friehs I. Wu Y. Levitsky S. et al. Intracoronary delivery of mitochondria to the ischemic heart for cardioprotection. PLOS One. 2016; 11: e0160889https://doi.org/10.1371/journal.pone.0160889 Crossref PubMed Scopus (125) Google Scholar ,3 Kaza A.K. Wamala I. Friehs I. Kuebler J.D. Rathod R.H. Berra I. Ericsson M. Yao R. Thedsanamoorthy J.K. Zurakowski D. et al. Myocardial rescue with autologous mitochondrial transplantation in a porcine model of ischemia/reperfusion. J. Thorac. Cardiovasc. Surg. 2017; 153: 934-943https://doi.org/10.1016/j.jtcvs.2016.10.077 Abstract Full Text Full Text PDF PubMed Scopus (115) Google Scholar ,4 Blitzer D. Guariento A. Doulamis I.P. Shin B. Moskowitzova K. Barbieri G.R. Orfany A. del Nido P.J. McCully J.D. Delayed transplantation of autologous mitochondria for cardioprotection in a porcine model. Ann. Thorac. Surg. 2020; 109: 711-719https://doi.org/10.1016/J.ATHORACSUR.2019.06.075 Abstract Full Text Full Text PDF PubMed Scopus (0) Google Scholar as well as to rescue the diabetic heart, 5 Doulamis I.P. Guariento A. Duignan T. Orfany A. Kido T. Zurakowski D. Del Nido P.J. McCully J.D. Mitochondrial transplantation for myocardial protection in diabetic hearts. Eur. J. Cardiothorac. Surg. 2020; 57: 836-845https://doi.org/10.1093/EJCTS/EZZ326 Crossref PubMed Scopus (0) Google Scholar with improved cardiac function and a reduction in infarct size.