A dynamic interpretation of quantum phenomena based on an energy driven time arrow requires a combined description of matter and information on matter. This information around matter turned out to be gravitation and the fact that a photon is continuously recycled via this information generates an always constant light velocity. These two phenomena, simple consequences of fundamental irreversibility, have mathematically been imposed on empty space for time-neutral spacetime in General Relativity theory. In an irreversible universe such a four-dimensional spacetime would not anymore be required. Another striking difference is the role of time. Clock-time, used in Relativity Theory and found to be relative, is not associated with a generation of changes, being only a scale for measuring changes, based on selected periodic phenomena. The real time in an irreversible world, action time, is the flow of action, as generated by the principle of least action, or, alternatively, the loss of information on the past. In contrast to clock-time, action time is invariant with respect to relativistic transformation and also facilitates self-organization of matter and information. Gravitation as information on matter with the aim of imposing the principle of least action also provides the link between quantum world and cosmology, which Relativity Theory cannot provide. Relevant aspects of both theoretical approaches, with special emphasis on already experimentally verified spacetime phenomena, are critically analysed. While Relativity Theory, which is relying on time-neutral laws, is applied to support a chaotically exploding Big Bang scenario, the fundamentally irreversible universe subject to an energy driven time arrow is characterized by self-organization of energy, matter and information yielding an intelligent and creative “Self-Image” universe, which is able to periodically regenerate itself. Arguments for a fundamentally irreversible energy driven nature include, apart from explaining experimental support for Relativity Theory differently, the simple, straightforward derivation from a dynamically interpreted principle of least action, the elimination of quantum and cosmological paradoxes and the more sensitive and flexible information-technology based (digital) nature of gravitation as compared with the analogue “bent space” gravitation.