You have accessJournal of UrologyCME1 Apr 2023MP31-19 PHYSICAL COMPONENT SCORE IN HEALTH-RELATED QUALITY OF LIFE (HRQOL) DECLINES SLOWLY IN MARGINAL LIVING KIDNEY DONORS Tomoaki Yamanoi Tomoaki YamanoiTomoaki Yamanoi More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003264.19AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: There are few reports on the health-related quality of life (HRQOL) in marginal living kidney donors (MDs) with medical problems such as hypertension and age. We assessed the change in HRQOL of MDs with that of standard donors (SDs). METHODS: Of the patients who experienced kidney donation at our hospital between February 2009 and April 2021, we evaluated 81 patients (40 SDs and 41 MDs) who were able to continuously have their QOL scores using Short Form 36 Health Survey (SF-36). MDs were defined according to Japanese guideline criteria (Table 1) We retrospectively compared renal function, cardiovascular disease (CVD) complications, occurrence of new malignancies, and HRQOL until 60 months post-donation. RESULTS: There was no significant difference between the two groups in postoperative renal function, the occurrence of CVD and malignant tumors. Preoperatively, QOL summary scores were higher than the general population (mean 50), and there were no significant differences between the two groups. In the postoperative physical component scores (PCS), the MD group was significantly lower than the SD group at 1 year (54.6 vs 49.7, p<.01), 3 year (53.3 vs 47.4, p<.05), and 5 year (52.7 vs 49.5, p<.05) (Figure 1a). Postoperative mental component score (MCS) was higher than the general population, and there was no significant difference between the two groups (Figure 1b). Multivariate logistic regression analysis high BMI (p<.05) and older donors (p<.05) had a significant independent association with reduced PCS. CONCLUSIONS: Although the preoperative HRQOL in marginal living kidney donors is better than general population, the postoperative PCS in the MD group tends to be lower than general population over time. Source of Funding: The authors declare no conflicts of interest associated with this manuscript © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e437 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Tomoaki Yamanoi More articles by this author Expand All Advertisement PDF downloadLoading ...