Abstract: This paper presents the design and implementation of a PMOS integrated current mirror tailored for biomedical applications. Current mirrors are fundamental building blocks in analog circuit design, finding extensive use in various signal processing stages, including amplification, filtering, and signal conditioning, critical in biomedical instrumentation. The proposed PMOS current mirror offers several advantages suited for biomedical applications, such as low power consumption, high input impedance, and compatibility with standard CMOS processes, ensuring seamless integration with other circuitry on a chip. The design focuses on achieving high accuracy and stability to facilitate precise measurement and processing of biomedical signals, essential for applications like biosensing, medical imaging, and neural interfacing. Simulation results demonstrate the efficacy of the proposed PMOS current mirror in meeting the stringent performance requirements of biomedical devices while offering robustness against process variations and environmental noise. This work contributes to advancing the state-of-the-art in integrated circuit design for biomedical applications, promising enhanced reliability and efficiency in nextgeneration healthcare technologies.