The conceptual design stage is an indispensable and important stage in the development of the modern body. However, due to the lack of sufficient body structure parameter support, the design defects generated at this time are difficult to make up for in the subsequent design stage. Therefore, it is of great significance to develop a conceptual design software for body structure that integrates design, analysis, and optimization. This paper proposes an intelligent body frame structure modeling and optimization system based on conceptual design, S-iVCD (Intelligent System for Conceptual Design of Vehicle Body Structure). Based on deep learning methods and body design sketches, a conceptual model of body structure is quickly established. Based on the data parameters stored in the Excel table, the system is seamlessly connected to the domestic independent finite element software SIPESC to calculate the simulated working conditions. The body structure optimization module is driven by the MMA (method of moving asymptotes), and takes the body structure performance and total mass as the optimization goals or constraints of the mathematical model to achieve body structure performance improvement and lightweight design.