Spin-off Companies Research Articles

Eye movement desensitization and reprocessing: Exploratory validation study of the potential of a biofeedback digitized approach for burnout therapy optimization

IntroductionThe Eye Movement Desensitization and Reprocessing (EMDR) therapy has shown to be useful in the treatment of PTSD, general anxiety, stress and burnout. Nonetheless, assessing therapy progress has been limited to subjective appreciations of the patient and therapist, which compromise therapy efficacy, and the continuum of care (clinic and at home) and scalability that digitized approaches can offer.ObjectivesThe aim of the present study was to validate the potential of a smartphone-based biofeedback digitized approach for EMDR usage in burnout therapy, as a means to provide quantitative progress assessment and personalized therapy optimization.MethodsA digitized burnout status assessment app based on Maslach Burnout Inventory was first implemented and tested. Then, an EMDR app was developed by making use of adjustable audiovisual stimuli (e.g. different velocity and horizontal/vertical visual stimuli; and different pitch and left-right surround sound effects) and also of the smartphone’s camera photoplethysmography finger recordings from which heart rate, heart rate variability and breathing rate are derived and used for modulating stimuli (biofeedback). Finally, interviews with several EMDR experts were conducted to assess the potential of the app as a therapeutic adjuvant.ResultsThe preliminary interview results showed that the app can be useful for online therapy, to optimize the stimuli presentation, and to quantify the therapy experience and outcomes. The interviews also validated the technical specifications and usability of the tool.ConclusionsResults so far have shown a promising receptivity and interest from EMDR experts. As such, patient testing is currently on-going.DisclosureThe work of the present abstract is the basis of the research conducted at the Faculty of Sciences of the University of Lisbon, co-lead with NEVARO, a spin-off company of the same Faculty.

대학 및 대학창업기업의 겸직종업원에 의해 창출된 직무발명 및 특허에 대한 두 사용자의 권리지분율 산정방법

대학교수 홍길동이 대학창업기업을 창업하는 사례가 적지 않다. 그 경우, 홍길동은 대학교수의 직위와 대학창업기업의 종업원의 직위를 겸직하게 되므로, 홍길동이 창출하는 직무발명의 권리관계가 복잡해진 다. 특히, 그 직무발명이 큰 수익을 유발하는 경우 대학과 대학창업기업 사이에 분쟁이 촉발된다. 실제로, 서울대-툴젠 사건이 발생하였는데, 그 사건을 양측이 어느 정도라도 납득할 수 있게 해결하는 특허법적 방안이 제시된 바가 없다. 이 글은 유사한 사안에서의 해결방안을 다음 과 같이 제시한다. 첫째, 일반적으로는 대학(대학교수 홍길동 포함) 및 대학창업기업(종업원 홍길동 포함)이 같이 공헌하여 해당 직무발명을 창출한다. 즉, 해당 특허에 대해 대학 또는 대학창업기업이 지분을 전혀 가지지 못하는 사례는 매우 드물다. 둘째, 그 공헌된 바(input)에 비례하 여 해당 직무발명, 나아가 특허에 대한 지분율(output)을 산정하여야 한다. 셋째, 그 공헌에는 발명자의 창작적 요소 외에 연구비, 기자재, 보조인력, 기존 지식 등의 비창작적 요소가 포함된다. 발명의 창출을 위해 발명자의 창작적 공헌만 필요한 것이 아니라 비창작적 요소의 공헌도 필요한 것이다. 넷째, 전체 발명의 창출에 비창작적 요소가 공헌하는 비율은 판례의 평균치에 따르면 80%에 달하며, 그 수치는 해당 기술분야, 해당 연구개발의 특수한 상황 등에 따라 조정되어야 한다. 다섯째, 발명의 창출까지 대학 및 대학창업기업이 비창작적으로 공헌한 비율, 각 X% 및 Y%, 대학의 발명자 및 대학창업기업의 발명자의 창작 적 공헌의 합을 각 P% 및 Q%로 파악한 후, 비창작적 요소의 공헌도 80%를 적용하여 대학 및 대학창업기업의 특허권 지분율을 산정하는 방법을 다음 표와 같이 제시한다.

Financial performance studies of university spin-off companies (USOs) in the West Midlands

Doubts remain over the true impact of university spin-offs (USOs), particularly those created outside elite research universities. This paper examines the financial performance of USOs from a single UK post-industrial region, the West Midlands within the framework of signalling theory. It adds to the existing literature on USO performance at company level, a currently under-represented topic, despite the attention and funding devoted to USOs by UK policymakers. By considering a single region, it brings new insight into the regional context of USOs. Key results of the study are a correlation between research strength of a university and ability of its USOs to attract external finance, but a lack of successful exits across the whole region.

Współpraca przedsiębiorstw turystycznych z uczelniami - wyniki badania empirycznego

The growing importance of the cooperation between enterprises and universities stems from the continuous search for new development sources and the need to ensure sustainable competitive advantages. However, research on the partnership between the universities and service enterprises is still relatively rare. The study presented in this article aimed to recognize the scope and character of cooperation between universities and service enterprises represented by the tourism businesses, as well as the attitudes of entrepreneurs towards such collaboration. The research was carried out on a sample of 383 enterprises. Its results revealed a relatively high level of cooperation (declared by 54.6% of entities) mainly in two simple forms: students’ internships and participation of business representatives in conferences organized by academia. They also allowed identifying that the size and operating time significantly differentiate the use of academic knowledge in enterprises. The results show that the overall perception of cooperation between the tourist businesses and universities is positive, and its advantages are well recognized. The most important among them is the increase in the employees’ competences and improving the company image due to contacts with academia. However, the more significant benefits of such cooperation may be achieved only when more advanced knowledge transfer mechanisms are applied, such as commissioned research or spin-off companies.

Obstructive Sleep Apnoea Syndrome Screening Through Wrist-Worn Smartbands: A Machine-Learning Approach

Background. A large portion of the adult population is thought to suffer from Obstructive Sleep Apnoea Syndrome (OSAS). Screening the general population for this syndrome is therefore crucial since this pathology has been associated with increased morbidity and mortality. However, current screening methods are based on questionnaires that intrinsically lack of objectivity. On the other hand, wrist-worn smartbands are non-invasive and economically convenient devices, which allow for prolonged monitoring of physiological parameters. Methods. We used accelerometric and photoplethysmographic data collected via commercial smartbands to train a machine-learning (ML) classifier assessing the presence and severity of OSAS. Each of the 78 patients who participated in this study underwent cardiorespiratory monitoring (CRM), a diagnostic method used to assess OSAS and its severity according to the Apnoea-Hypopnoea Index (AHI). Findings. According to the Matthews Correlation Coefficients (MCC), the proposed algorithms reached an overall good correlation with the ground truth (CRM) for AHI<5 vs AHI≥5 (MCC: 0.4) and AHI<30 vs AHI≥30 (MCC: 0.3) classifications. AHI<5 vs AHI≥5 and AHI<30 vs AHI≥30 classifiers’ sensitivity, specificity, positive predictive values (PPV), negative predictive values (NPV) and diagnostic odds ratio (DOR) are in line with the ones of the STOP-Bang questionnaire, a OSAS screening tool widely adopted in the clinical practise. Interpretation. The consumer accelerometric and photoplethysmographic data, continuously collected and stored, could guide OSAS large scale screening also in a retroactive way, ideally triggering an alert for those users in need of further diagnostic investigation of the risk of OSAS.Funding. Arpa Foundation. Declaration of Interest: Ugo Faraguna and Umberto Olcese are co-founders of sleepActa S.r.l, a spin-off company of the University of Pisa operating in the field of sleep medicine. All other authors declare no competing interests. Ethical Approval: This study was approved by the Pisa University Hospital Bioethical Committee (CEAVNO protocol No: 42714). Participants provided written informed consent to take part in the study.

STRATEGIC MODEL OF TRANSFORMATION OF INNOVATIVE INFRASTRUCTURE OF THE DONETSK ECONOMIC REGION IN THE RUNNING REINTEGRATION PERIODS

Objective. The objective of the present article is to analyze the current, pre-reintegration models of transformations of innovation infrastructure in the region, to determine a promising strategic model of trans­formation of innovation infrastructure of Donetsk economic region in the reintegration period according to the tried and tested author’s approach to understanding. Methods. The following general scientific methods and techniques of cognition were used in the research process: theoretical generalization and comparison, analysis and synthesis, induction and deduction, group­ing. Results. According to the results of the study it is substantiated that the development of innovation infra­structures is a process of permanent successive multidimensional (spatial, temporal, material and structural) transformations of innovation infrastructures, resulting in static and dynamic effects, quantitative and quali­tative changes in innovation infrastructures and / or national economies. It is established that the most effec­tive model of innovation infrastructure development is the model of managed development, which provides for the definition and justification of the most promising strategic model for the transformation of innovation infrastructure. The strategic model of innovation infrastructure transformation is proposed to be understood as a long-term plan of transformations, changes in all dimensions of innovation infrastructure, aimed at improving the efficiency of its functioning, increasing the level of innovation of the country and its national economy.Based on the study of regulatory and legal support for the development of innovation and innova­tion infrastructure of Ukraine and Donetsk economic region, it is established that both current and pre-re­integration model of transformation of innovation infrastructure of Donetsk economic region and Ukraine as a whole are fragmentary and unsystematic. countries. It is substantiated that the perspective strategic model of transformation of innovation infrastructure of Donetsk economic region in reintegration period should be based on Quadruple Helix Model, be directed on: deployment, reconfiguration (the main priority should be development of providing functional component of innovation infrastructure Priority should be given to the development of spin-off companies, spin-out companies, living laboratories, centers of excellence, coworking centers, competence centers, including digital competences, technopolises and other innovation ecosystems) and improving the efficiency and development of existing structural elements of innovation infrastructure of Donetsk economic region. The practical significance of the obtained results lies in the possibility of their use in the development strategy and increase the competitiveness of the Donetsk economic region.

Cooperation and relationship in the triple helix model of innovation

During the last decades the cooperation between universities, companies and government has helped generate new knowledge, transfer technology and create incubators of small and medium enterprises (SME), and spin-offs. The triple helix model, which is the focus of this research, represents a paradigm for the university within this three-way relationship, with the development of the entrepreneurial university concept. In fact, business-minded universities have grown significantly in socio-economic terms, with the development and registering of patents, as well as in activities related to spin-offs. Spin-off companies created from universities help transfer knowledge and scientific research to the business sector, and facilitate communication between universities, the market and society. In recent years, technological change and cooperation between business and universities have become increasingly important. Competition in business, and the need for companies to collaborate more closely, is reshaping universities in terms of the research they undertake and their relationship with the state.

Developing University Science and Technology Company in Vietnamese Public Universities

This research focus on current situation of university spin-off company in public university in Vietnam to analysis the reason of limitation and propose some proposal to develop the university spin-off company. In the scope of this research, author focus on the university spin-off company in famous university in Hanoi to find out the problems of this model. Beside the secondary data, author used indepth interview with experts who are the leaders of these univerisy to deeply understand the problem of these model. The interview results and the previous research, author indicates ten objective reasons and two subjective reasons of government-based organization. Some policies proposal and strategy for developing university spin-off company in public university.

The Evolutionary Model of Corporate Entrepreneurship: A Case Study of Samsung Creative-Lab

Despite international interest in corporate entrepreneurship research, relevant knowledge has not been systematically accumulated. Even in practice, the discussions of corporate entrepreneurship revolve around the appropriate level necessary and the preferred method of action. This paper proposes an evolutionary model that outlines corporate entrepreneurship overall in terms of an organization’s entrepreneurial activities. For the research objective, this paper includes in-depth case studies on Samsung’s Creative Lab. The Creative-Lab of Samsung has been actively implementing corporate venture system for eight years. We conducted collective case studies by focusing on a single case (Creative-Lab) and then moving to multiple cases (Creative-Lab spin-off companies). Firstly, the study identifies the development process of entrepreneurship from the individual-level to the firm-level, and from the firm-level to the social-level. Secondly, the study confirms that corporate venturing and the corporate spin-off system have a positive impact on entrepreneurial behavior, which is crucial to seize opportunities. Thirdly, based on the growth factors and performance of corporate entrepreneurship, an evolutionary model of corporate entrepreneurship is proposed in this paper. This study can contribute to the establishment of an integrated and structured mechanism of related research as it comprehensively reviews the antecedents, elements, and outcomes of corporate entrepreneurship.

What can research organizations learn from their spin-off companies? Six case studies in the water sector

Spin-off companies are generally considered a promising vehicle for developing academic knowledge into products that are ready for the market. In this paper the authors explore under what circumstances spin-off companies can serve as a source of knowledge for the research organization from which they originate. The paper brings together literature from different academic fields to construct an analytical framework for investigating knowledge feedback mechanisms between spin-off companies and their parent research organizations. The authors illustrate the application of this framework in six case studies of parent–spin-off couples in the water technology sector. These case studies show that the interaction with spin-off companies can yield important cognitive benefits for the academic research process, such as an improvement of the research agenda and new insights about the practical operation of theoretical models and technologies. These benefits were facilitated mainly by staff exchange, collaborative research and personal contacts.

Pathways to academic entrepreneurship: the determinants of female scholars’ entrepreneurial intentions

Female entrepreneurship is somewhat rare in the academic sphere, and female scientists tend to set up spin-off companies less frequently than their male colleagues. Despite the relevance of the entrepreneurial role of universities for economic and social development and the particular attention of female entrepreneurs to these aspects, studies on the topic are still sparse and fragmented. This study aims to investigate female academic entrepreneurship, by verifying whether and under what conditions the antecedents of entrepreneurial intentions can explain it in depth. For this aim, the study offers an integrated view of the literature on entrepreneurial intentions and academic entrepreneurship, through a gender perspective. Fifty-two academic researchers, affiliated to 13 different university departments, are involved in the study. The fsQCA is used to analyze the data collected and the complexity of the entrepreneurial journey. The results obtained highlight different scenarios and implications related to female academic entrepreneurship.

연구소기업 설립 정책의 활성화 요인 분석 : 정책집행주체의 태도 중심으로

정책이 성공하기 위해서는 집행을 담당하는 정책집행주체의 태도가 중요하다. 본 연구는 일정 시점 이후 연구소 기업이 급증한 것을 설명하기 위해, 정책집행기관의 태도에 집중하여 시기별로 분석을 진행했다. 연구소기업 제도가 시행된 2006년부터 2013년(정책집행 1기)까지 정책집행기관은 규범적이고 형식적으로 정책에 순응하는 모습을 보였다. 그 결과 소극적으로 정책이 집행되었고, 정책 산출물인 연구소기업의 설립도 연 평균 5.8개로 미흡한 수준이었다. 반면, 2014년 이후(정책집행 2기)에는 정책집행기관의 태도에서 정책 수행에 대한 내적 인식의 변화를 동반하는 수용의 모습이 발견된다. 이 시기 적극적이고 주도적인 정책집행은 연 평균 140.8개의 연구소기업이 설립되는 기반이 되었다.<BR> 형식적 순응에서 정책 수용 단계로 진화한 정책집행기관의 태도가 연구소기업 설립 급증에 정성적 영향을 미쳤다는 것을 처음으로 검토하였고, 이를 통해 정책집행기관의 관점에서 향후 연구소기업 정책 운영을 위한 시사점을 제시하였다는 점이 본 연구의 의의라 할 수 있다.

The Relevance of the Economic Environment to the Development and Growth of Academic Spin-Offs. A Panel Approach

The importance of academic research (&amp;quot;AR&amp;quot;) to economic growth is widely accepted but quantification of incremental impacts, and their attribution to any one country&amp;#39;s expenditures, is difficult. Yet quantitative justification of government AR funding is highly desirable. We therefore attempt to quantify one impact which can be directly and causally attributed to one country&amp;#39;s funding: spin-off companies.&#x0D; &#x0D; Although there is great interest in the new knowledge economy, less favoured regions seem permanently disadvantaged because they lack a critical mass of knowledge capital to initiate accumulation, growth and economic development processes. This is a problem for policy-makers seeking to promote economic growth and territorial cohesion in such regions. This paper seeks to develop four empirical models of how Academic spin-off companies can improve their economic performances. The economic benefits that such companies bring are explored, to identify those elements which can potentially upgrade regional economies through knowledge accumulation, which are termed &amp;lsquo;building up territorial knowledge pools&amp;rsquo;.&#x0D; &#x0D; We argue that the impacts of valid and ongoing policies in support of the Third Mission represent incremental contributions to the ROI of academic spin-offs, much greater (also on a updated base). The impacts therefore provide a quantitative justification for public investment, allowing much more important (but less quantifiable) long-term benefits be considered as a &amp;quot;free&amp;quot; bonus.

LA ENTREPRENEURIAL UNIVERSITY: TOOLS AND MODELS FOR INTEGRATING THE THIRD MISSION IN EDUCATION INSTITUTIONS

University spinoffs have remarkably strengthened the linkage between universities and industry. The number of technology patents and spinoffs coming out of university research has a significant impact on regional economic and social development. To further highlight the importance of university spinoffs, the article aims to review available literature on university spinoffs and present a comprehensive overview of what university spinoffs are, why they are important, what makes them significant, and how they are or can be created. In addition to reviewing existing models of University spinoff creation, the authors propose a new, multi-stage, holistic model.&#x0D; The authors explore how universities can promote new research-based businesses by suggesting that the nature of the supplied support depends on demands of spin-off companies. Adopting a demand-side perspective, the authors seek to understand the challenges faced by new technology businesses and hence identify how universities can assist their start-up and development.&#x0D; The paper nuances the common conception of a university as one uniform entity in relation&#x0D; to spin-offs, and assesses the literature including all levels within the university. The analysis of EU spin-off models, activities, methodologies and policies is based on the outcomes of the ERASMUS+ project “University-Enterprise Cooperation via Spin-Off Companies Network (UNISON)”.

The Importance of Academic New Ventures for Sustainable Regional Development

Establishment of new entrepreneurial ventures have a direct influence on economic growth of the economy and society of every country. It relates especially to unemployment level and net income of the employees. Given these facts, the two aims of the paper are: 1) presentation of the Innovativeness of 14 countries of South – East Europe region and two additional countries: Poland and Hungary based on their overall ranking(s) as well as Information and Communication Technologies, ICT access and ICT use; and 2) to present development and business performance of academic start-up and spin-off companies in ICT sector which were created by the University of Novi Sad (Serbia) and which allowed it to become a sustainable University. The indicators such as total number of new ventures, number of employees, total revenue and average gross profit margin were used in order to analyse establishment, development and sustainability of academic ICT start-up and spin-off companies. The study shows that sustainable measures, particularly academic start-up and spin-off companies, have a very important role in sustainable economic growth (local, national and regional) and are a significant driver of innovation. They are of key importance for the sustainable development of the University.

(Keynote) Engineering Research Centers –Past, Present and Future

During the recent decades, the scientific and engineering community and the federal agencies have explored the potential of large-scale center-type research programs. It has been recognized that many of the most challenging and complex technical problems can only be addressed if researchers with diverse expertise combine their efforts and work across the boundaries between disciplines. The National Science Foundation (NSF) Engineering Research Center (ERC) program is a flagship program in this regard.The ERCs are interdisciplinary, multi-institutional centers that join academia, industry, and government in partnership to produce transformational engineered systems and educate individuals that are adept at innovation and primed for leadership in the global economy. They operate at the interface between the discovery-driven culture of science and the innovation-driven culture of engineering. Since the ERC program’s inception in 1984, NSF has funded over 70 ERCs across the United States. The NSF funding level has been at about $4 million per year for each ERC for up to 10 years, during which time the centers would develop partnerships with industry, universities, and other government entities to sustain them upon graduation from NSF support. Throughout the years, the ERCs have contributed significantly to the technical community and the nation; educated more than 12,000 engineering graduates with interdisciplinary training, produced a tremendous amount of high impact publications, patents and licenses, and spin-off companies. Studies have estimated that the total downstream market value of ERC innovations to the U.S. economy is well over tens of billions of dollars. Recently, NSF funded the National Academies of Sciences, Engineering, and Medicine (NASEM) to conduct a study to create a vision for future research centers in engineering (A New Vision for Center-Based Engineering Research, 2017, The National Academies Press). Building upon the NASEM’s recommendations, NSF developed a roadmap for the next generation of ERCs (Gen-4), which emphasizes cutting-edge research efforts that are convergent and will lead to strong societal impact. A Gen-4 ERC will have interacting foundational components that cover convergent research, workforce development, culture of diversity and inclusion, and innovation ecosystem. This presentation will provide an overview of the NSF ERC program to date, as well as new opportunities for the Gen-4 ERCs.

(Invited) Direct Ammonia Polymer Electrolyte Fuel Cell

Ammonia is a liquid fuel of high energy density and low storage pressure. These properties facilitate storage, distribution and fueling, as required for the introduction and acceptance of an alternative fuel. Distributed as liquid, ammonia cost is projected to be 30% lower than that of hydrogen distributed as compressed gas.1 The structure of direct ammonia fuel cells (DAFCs) is illustrated in Figure 1a.The hydroxide exchange membrane employed in our DAFCs work was the poly(aryl piperidinium) (PAP) membrane developed at the University of Delaware2 and at the spin-off company, W7energy LLC. Following optimization of the composition of the catalyst layers and the operation conditions, the performance of an ammonia oxygen cell at Tcell= 95 oC reached the peak power level of 580 mW cm-2 (shown in Figure 1b).A remaining significant challenge has been the DAFCs performance stability, with testing at constant current showing unstable voltage followed by the fall of the voltage to zero after only a few hours. Recognizing the origin of the instability as liquid management in the DAFCs anode, recent optimization of the anode structure improved substantially the voltage stability with the earliest test showing this improvement, which is depicted in Figure 1c. 1. Y. Zhao, B. P. Setzler, J. Wang, J. Nash, T. Wang, B. Xu, and Y. Yan, Joule, 3, 2472-2484 (2019)2. J. Wang, Y. Zhao, B. P. Setzler, S. Rojas-Carbonell, C. B. Yehuda, A. Amel, M. Page, L. Wang, K. Hu, L. Shi, S. Gottesfeld, B. Xu, and Y. Yan, Nature Energy, 4, 392–398 (2019) Figure 1

Knowledge spillovers, knowledge filters and entrepreneurial university ecosystems. Emerging role of University-focused venture capital firms

ABSTRACT In this study, we analyse the role played by investment managers from University-focused Venture Capital firms (UVCs) in knowledge spillovers in Entrepreneurial University Ecosystems (EUEs). Data from fifteen in-depth interviews with key agents of the EUEs in England was examined through the lens of the Knowledge Spillover Theory of Entrepreneurship, using Social Network Analysis and qualitative analysis. We identified the emerging role of UVCs as key knowledge intermediaries in developing and sustaining EUEs, concluding that UVCs are key to overcoming knowledge filters and maintaining dynamic relationships over time between entrepreneurial universities and University Spin-off companies. In this paper, we describe how UVCs act as social connectors, facilitating a two-way knowledge and technology exchange necessary in the development and sustainment of EUEs.

Retraction of "Cyclodextrin Metal-Organic Frameworks: From the Research Laboratory to the Marketplace".

ConspectusCyclodextrin-based metal-organic frameworks (CD-MOFs), derived from γ-cyclodextrin (γ-CD) and potassium ions, constitute a new class of porous, renewable, and edible MOFs that can be synthesized wholly from naturally occurring starting materials on a large scale. γ-CD is a C8 symmetrical cyclic oligosaccharide, composed of eight asymmetric α-1,4-linked d-glucopyranosyl residues, which possesses a bucket-shaped cavity with an inner diameter of ∼1 nm and a depth of ∼0.8 nm. Upon combining 1 equiv of γ-CD with 8 equiv of potassium hydroxide in aqueous solution, followed by vapor-diffusion of MeOH (or EtOH) into the solution during several days, CD-MOF-1 is obtained as cubic crystals. It was discovered serendipitously in 2010 as the first CD-MOF with a cubic cell of space group I432 and unit cell dimensions of approximately 31 × 31 × 31 Å3. Other CD-MOFs, namely, CD-MOF-2 and CD-MOF-3, can be obtained, respectively, wherein potassium is replaced with rubidium and cesium ions. CD-MOFs comprise infinite body-centered frameworks of (γ-CD)6 cubic units linked by alkali metal cations with spherical pores which reside at the center of the cubes interconnected by both cylindrical and triangular channels.During the past decade, CD-MOFs have emerged as a new class of multifunctional materials based on a porous framework with an extended structure displaying robust crystallinity, permanent porosity, and biocompatibility. The family of CD-MOFs has been enlarged by a growing collection of metal nodes involving alkali metal cations (Li+, Na+, K+, Rb+, Cs+) and γ-CD as well as its derivatives. As a result of the ability of their porous extended frameworks to absorb guest molecules, including gases, drug molecules, metal-based nanoclusters, and nanoparticles, CD-MOFs have potential applications in areas as disparate as adsorption and separation, sensing, template syntheses of metal-based nanoparticles and gels, electrical memory, drug delivery, and catalyst stabilization.In this Account, we tell the story of CD-MOFs, a scientific discovery that was made in our research laboratory at the Northwestern University, and the subsequent commercialization of CD-MOF technology on the part of a spinoff company, which developed a line of successful skin care products. This Account includes representative synthetic methods for the preparation of CD-MOFs, along with a brief overview of their structural features and a general summary of their state-of-the-art applications. The examples, however, are only illustrative, and a significant body of additional findings is emanating from our own laboratory and others, especially in the development of new synthetic strategies, tuning the framework stabilities, and exploring the guest-inclusion properties of CD-MOFs. We refer readers to communications, papers, and reviews on CD-MOFs and to references therein. We also put on record how CD-MOFs have been rebranded as organic molecular vessels (OMVs), a smart, functional, environmentally friendly delivery platform for commercial skin care applications. We hope that, in the telling and retelling of the story of CD-MOFs, this Account may encourage the commercialization of discoveries that have been made in other research laboratories.

Design, Data and Liveability: The Role of Technology Within the Future of an Expanded Profession

AbstractBen van Berkel, co‐founder of Amsterdam‐based UNStudio, believes that architectural practice has been invigorated by the myriad of cultural, societal and technologic parameters that a contemporary architect must consider. The practice recently formed a spinoff company, UNSense, to develop and commercialise technologies emerging out of UNStudio's smart city and smart environment projects. Here he describes some of the products, prototypes and startups the studio has developed to help tackle some of the important issues of our time: stress, urban water and climate change.