A new species of Cyrtodactylus described from Nyemo County, Xizang Autonomous Region, China is here referred to a new species, Cyrtodactylus zhaoermii sp. nov. It is distinguished from all other Cyrtodactylus by the following characters: dorsal surface of the body with fine granules intermixed with larger sub-conical tubercles arranged into 20 more or less regular rows; proximal subdigital lamellae transversely expanded; 19–20 subdigital lamellae on toe IV; 30–32 midbody ventral scales; most scales in femoral region small, granular, series of 12–14 enlarged femoral scales lacking pores; a series of precloacal pores (4) present in male; tail with distinct segments, large, posteriorly directed tubercles in whorls, numbering nine to ten per caudal annulus, three on each side and three to four on the dorsum, situated at the posterior edge of each annulus; subcaudals not transversely expanded. The new species is the fourth Cyrtodactylus known from Xizang Autonomous Region.