Special Group Research Articles

Optimization and standardization of the work of a health care facility during a chemical accident

During the years of war, as a result of aviation and missile attacks, a significant number of health care facilities in various regions of Ukraine were destroyed, and the complexity and intensity of their work increased significantly. If the readiness of hospitals and their employees to treat gunshot and explosive injuries is established, in the case of mass destruction of chemically hazardous enterprises and the threat of the enemy using weapons of mass destruction, including chemical weapons, there is a need for special training of health care facilities to work in the in conditions of chemical threats. The aim of the work was justification of the development and set of measures for the implementation of standard operating procedures in the event of a chemical incident. The legal documents and recommendations of the Ministry of Health of Ukraine, management of the World Health Organization and the Red Cross on the topic of the study were used. The research methods: bibliosemantic, analytical, modeling were applied. It is established that the special management group, which includes representatives of various services, is of decisive impor­tance in the effective management of a health care facility during a chemical incident: administration; communication department; security department; management of nurses and the department of infection control; human resources department; pharmacy; intensive care unit; department of engineering maintenance and repair; laboratory; kitchen; laundry; cleaning service and waste management. The most important measures of response to a chemical incident that ensure the safety of medical personnel and patients are the organization of a triage zone and a decontamination area for chemically affected persons. Based on the above, to prepare a health care facility for work during a chemical incident, it is necessary to develop a response plan, which consists of special administrative and management decisions and provides for regular staff training.

Mendelian randomization as a cornerstone of causal inference for gut microbiota and related diseases from the perspective of bibliometrics.

Gut microbiota, a special group of microbiotas in the human body, contributes to health in a way that can't be ignored. In recent years, Mendelian randomization, which is a widely used and successful method of analyzing causality, has been investigated for the relationship between the gut microbiota and related diseases. Unfortunately, there seems to be a shortage of systematic bibliometric analysis in this field. Therefore, this study aims to investigate the research progress of Mendelian randomization for gut microbiota through comprehensive bibliometric analysis. In this study, publications about Mendelian randomization for gut microbiota were gathered from 2013 to 2023, utilizing the Web of Science Core Collection as our literature source database. The search strategies were as follows: TS = (intestinal flora OR gut flora OR intestinal microflora OR gut microflora OR intestinal microbiota OR gut microbiota OR bowel microbiota OR bowel flora OR gut bacteria OR intestinal tract bacteria OR bowel bacteria OR gut metabolites OR gut microbiota) and TS = (Mendelian randomization). VOSviewer (version 1.6.18), CiteSpace (version 6.1.R1), Microsoft Excel 2021, and Scimago Graphica were employed for bibliometric and visualization analysis. According to research, from January 2013 to August 2023, 154 publications on Mendelian randomization for gut microbiota were written by 1053 authors hailing from 332 institutions across 31 countries and published in 86 journals. China had the highest number of publications, with 109. Frontiers in Microbiology is the most prolific journal, and Lei Zhang has published the highest number of significant articles. The most popular keywords were "Mendelian randomization," "gut microbiota," "instruments," "association," "causality," "gut microbiome," "risk," "bias," "genome-wide association," and "causal relationship." Moreover, the current research hotspots in this field focus on utilizing a 2-sample Mendelian randomization to investigate the relationship between gut microbiota and associated disorders. This research systematically reveals a comprehensive overview of the literature that has been published over the last 10 years about Mendelian randomization for gut microbiota. Moreover, the knowledge of key information in the field from a bibliometric perspective may greatly facilitate future research in the field.

AUTHENTICATION OF WIRELESS SYSTEMS BASED ON A DRONE SWARM AS A COMPONENT OF THE 5G RADIO ACCESS NETWORK ARCHITECTURE

Background. When establishing security measures for telecommunication networks involving unmanned aerial vehicles (UAVs), characteristics such as high scalability, device diversity, and high mobility should be considered. Authentication is a fundamental property that allows a UAV network to establish secure communication between its core components. Authentication also protects the UAV network from attackers impersonating legitimate UAVs. UAV authentication can further secure the communication channel by preventing impersonation and replay attacks. The design of UAV access control schemes, such as authorization and authentication mechanisms, remains a challenging research problem in UAV networks. The network becomes even more complicated when it interacts with a multitude of UAVs, called a swarm. A swarm by its very nature has a dynamic structure, and this raises the issue of unreliable constraints on UAVs in its composition. A standardized solution for the authentication of a single drone using the new 5G radio network (NR) is known, but for a swarm of drones, this is an open field of research. Per-UAV authentication key sharing as described in 5G NR does not scale across groups of UAVs. Objective. The purpose of this work is to conduct an analytical review and consider approaches to creating procedures for the authentication of a swarm of UAVs/drones with wireless equipment on board for the 5G NR network, taking into account the features of swarm formation and the very requirements for 5G authentication. Methods. Analysis of factors affecting the quality of provision of telecommunication services using UAVs in fifth generation networks. Analysis of well-known publications dedicated to the implementation of 5G networks and the use of drones in them. Comparing the implementation of UAV authentication procedures with on-board wireless equipment in the 5G network. Results. The widespread use of small UAVs, as well as the large expansion of wireless 5G networks, requires new security measures to prevent unauthorized access to sensitive data. Identification and Authentication for a mobile operator's network using drones allows for secure communication between its main components. This makes it possible to recognize the very drones that participate in the formation of such a network. Drone authentication often protects the communication channel by preventing replay attacks. The development of drone radio access control mechanisms, such as authorization and authentication mechanisms, remain relevant researches for the construction of promising radio access networks involving UAVs. It has been confirmed that the introduction of special group procedures for the authentication of a swarm of drones in the 5G network can significantly improve the quality of the provision of telecommunication services. Conclusions. When working with a swarm of drones, in addition to the usual problems with encryption and authentication (within the swarm and for communication between the swarm and the ground control station), there are additional problems related to the constant change in the composition of the swarm and its hovering position: drones can join or leave a swarm. Depending on the swarm management structure, a different method of authentication will be needed, which makes it difficult to unify such procedures for a swarm of drones. Authentication procedures for a swarm of drones in 5G can be implemented through the following approaches: individual authentication, when each drone as a member of the swarm undergoes authentication with one NR 5G ground station; you can consider such an approach as authentication of a group of IoT devices, if the traffic of the swarm is very limited; group authentication through a leader drone that communicates with swarm members and the 5G operator's network; group distributed authentication through edge drones. Group authentication via a drone leader is presented, where authentication is performed through a mechanism based on distributed delegation to reduce the service traffic directed to the 5G operator's core network. Here, legitimate drones are authorized as proxy delegated signers to perform authentication on behalf of the underlying network. Group distributed authentication through boundary drones is considered, which offers more solutions than the case of authentication through a leader drone. Here, a solution is possible for several cases at once, for example, authentication of new drones (entering the swarm or leaving the swarm) and merging two separate drone swarms.

От философии сознания к философии субъекта: самоотношение

Modern philosophy of mind focuses on such aspects of consciousness as perception, information processing, and qualia (also occurring in perception). At the same time, insuffi cient attention is paid to such conscious actions of the subject as decision-making and action. However, action requires no less consciousness than perception. It is not so much the philosophy of mind that deals with action as the philosophy of subject. This article makes a connection between the philosophy of mind and the philosophy of subject through the concepts of freedom and selfrelationship. The subject is essentially free because he makes decisions. Even if his decisions are determined by his biological arrangement or his history, he transforms past determinations into future ones, and still the decision-making occurs, so that some freedom is required. As for mind, it is also related to freedom because its light is lit in the same decision-making situations. There is a special group of decisions concerning subject’s relations. The subject’s relations to the world, to the Self, to the Others, to transcendence are considered. In relation to the world, the subject can manifest his freedom through self-restraint, renunciation of power, based on Heidegger’s maxim of “letting being be.” He can build his attitude towards Others in an ethical paradigm, for example, according to the teachings of Levinas. Transcendence can be given in the form of looking at oneself from the outside. A special group of actions of the subject is distinguished: self-attitude and self-action. In the fi eld of mind it is self-consciousness. The subject can modify his own attitudes based on the transcendent point that he himself posits. This also has implications for the choice of values. The religious relation to one’s own soul and Heidegger’s doctrine of transcendence are considered. Self-existence is a supremely free action of the subject through which he constructs himself.

Research Progress on Social Inclusion of Special Groups

Research Progress on Social Inclusion of Special Groups

Feminist discontents against multiculturalism: The need for critical multiculturalism

Multiculturalism and feminism both contest the undifferentiated notion of liberal democracy and its overemphasis on individual rights; however, the latter does not conform with the special group rights advocated by multiculturalism. This article explores the tension between the feminist idea of gender equality and the group-specific rights endorsed by multiculturalism. The claim of group-specific rights in multiculturalism does not consider internal gender inequalities. Hence, the article critically analyzes some cultural practices to demonstrate how culture is gendered and how multicultural advocacy of group-specific rights is insensitive to gender discrimination within cultural groups. It employs an integrative literature review as a methodology to assess the theory of multiculturalism and draws a feminist perspective to suggest a critical model of multiculturalism. It is concluded that multiculturalism is not sufficient to combat patriarchal repression embodied in the cultural groups. Thus, the article further seeks to forge a form of multiculturalism that is critical to its own shortcomings and is ready to accommodate gender equality.

Features of preposition usage in the diplomatic sub-style of the Russian and Chinese languages

The article is devoted to the use of prepositions in the diplomatic language of the Russian and Chinese languages. The subject of the study is the structural and semantic characteristics of prepositional constructions typical of the diplomatic substyle. The main goal is a comparative analysis of the preposition use as one of the diplomatic substyle linguistic features in the languages under consideration and the identification of their features in terms of their structure and meaning. To achieve this goal, methods of comparative analysis, statistical analysis and component analysis were used. Bilingual diplomatic documents from the official websites of the Ministry of Foreign Affairs of Russia and China over the period from 1994 to 2023 were selected as research material. As a result of the study, we conclude that prepositions are actively used in both Russian and Chinese diplomatic styles, but their structures and meanings differ. We have found that from the point of view of the constructions’ meanings, both languages possess prepositional constructions to express the meanings of goals, methods and bases. However, in the Chinese language there is a special group of prepositions expressing the subject or object of an action, while in the Russian language such meanings are conveyed using case forms.

Beggars cannot be choosers? Legitimacy deficiency and the use of trade credit by family firms

AbstractWhile prior literature conceives financial distress as the primary driver of trade credit usage, organisational idiosyncratic characteristics and the situated institutional environment may also play a role. Building on the legitimacy‐based view, this study investigates whether family firms (FFs) – a special group of firms that are relatively understudied in the finance and accounting literature – in transitioning economies like China exhibit unique patterns of the use of trade credit. We found that increased family ownership leads to more usage of trade credit. Such inclination is stronger among FFs undergoing intergenerational succession, whereas it is weaker for FFs located in more developed subnational regions.

Nonlinear static and dynamic analysis of corotational shell formulated on the special Euclidean group SE(3)

Nonlinear static and dynamic analysis of corotational shell formulated on the special Euclidean group SE(3)

Long-term risk factor management and adverse events in patients with early-onset myocardial infarction-a "real-world" study.

International guidelines emphasize the importance of preventive efforts after early-onset myocardial infarction (EOMI); however, data on "real-world" long-term risk factor management and adverse event rates in this special patient group is scarce. In this German registry study, 301 patients with MI aged ≤ 45years were investigated. Risk factor control was assessed at the time of index MI and after 1year. Major adverse cardiac and cerebrovascular events (MACCE) and its predictors were analyzed during long-term follow-up (median duration 49months). A majority of patients with EOMI presented with insufficient risk factor control, even during 1-year follow-up. After 1-year 42% of patients were persistent smokers; 74% were physically inactive. The rate of obesity increased significantly from index MI (41%) to 1-year follow-up (46%, p = 0.03) as well as the rate of dysglycemia (index MI: 40%; 1-year follow-up: 51%, p < 0.01) and diabetes mellitus (index MI: 20%; 1-year follow-up: 24%, p < 0.01). 66% of the patients with diabetes mellitus had unsatisfactory HbA1c after 1year; 69% of the patients did not attain guideline-recommended lipid targets. The rate of MACCE during long-term follow-up was 20% (incidence rate 0.05 per person-year). In a multivariable analysis smoking (HR 2.2, HR 1.3-3.7, p < 0.01) and physical inactivity (HR 2.8, HR 1.2-6.7, p = 0.02) were significant predictors for the occurrence of MACCE. Insufficient long-term risk factor control was common in patients with EOMI and was associated with an elevated rate of MACCE. The study reveals that better strategies for prevention in young patients are crucially needed.

Seasonal landscape variability advances Lantian hominin's recognition capacity to strategically adapt to changing environments

Environmental Variability Selection (EVS) is hypothesized for the emergence of early Homo (H.) sapiens with small lithic tools in Africa. Yet, it is unclear how the EVS works when a special hominin group with advanced small lithic tools evolved from the Asian H. erectus with expedient core and flake industry. Lantian loessland in southern Chinese Loess Plateau in North China preserves continuous and concentrated hominin fossil, faunal, pollen, stone tool, paleoclimate, and landform records for last 2 million years (Ma) and is an ideal place to test this hypothesis. We reanalyzed δ13C values of soil organic and inorganic carbon from 2 Lantian loess-paleosol records to partition seasonal climate and habitat changes with synthesized lithic, faunal, and pollen data to seek cluses. We found that Lantian Gongwangling and Chenjiawo H. erectus adapts to woodland-forest habitats, manufacturing Mode 1 stone artifacts foraging subtropical animals in warm and Paleoarctic animals in cool seasons on the low and medium-high rolling loessland, while more advanced Dali hominins adapt to certain steppe-shrubland habitats manufacturing diverse small-sized lithic tools to forage more open-habitat animals in all seasons on hilly landforms. We propose that co-evolution of seasonal habitat variability and changing local landforms in 2.0–0.2 Ma advances Dali hominin's cognitive capacity for strategically using landform morphology for subsistence and manufacture small stone tools for intercepting high fluxes of seasonal resources on highly variable loessland. Seasonal landscape variability and landform evolution is the key in the EVS for the evolution from Asian H. erectus to a more advanced hominin group or species.

First-Generation African Students in STEM Disciplines in South African Universities

ABSTRACT First-generation student (FGS) is a complex term, which has a wide diversity of individuals, this special group of students are the first in their families to attend universities and have unique struggles at universities. The research engaged in a qualitative way with FG African students and their experiences in pursuing their degrees in STEM disciplines. Underpinned by the theory of intersectionality, ten self-identified first-generation African students participated in semi-structured interviews. In which,five major themes were identified—motivation, resilience, toxicity, racism, and politics, and Black Tax. Furthermore, this study recommended structural programming, university policies, and increased faculty and staff diversity as strategies that will benefit all students and provide support for FG African student in STEM disciplines in South Africa.

Issues pertaining to posology in ancient Greek, Roman and Byzantine medical texts

Researching medical texts of the past reveals that the preparation of a therapeutic recipe usually involved the use of several active ingredients. There are many detailed reports on the ratio of the ingredients in a recipe, but also on the dosage administered to the patient. In this article, we recorded the use of units of weight and volume in therapeutic recipes from antiquity, the Hellenistic era, the Roman Empire, Byzantium, and also empirical medical texts of the 19th century. The changes emerging over time from the growing trade in the wider Mediterranean area, with the introduction of both new products and new units of measurement, did not affect the basic principles of the therapeutic methods. Through the centuries, the main concern of physicians was to fight the disease without burdening the patient with any unwanted effects. In this context, we observe even dosage modifications when it comes to special vulnerable population groups, such as children, the elderly and pregnant women. The period covered is very large, which means that the approach is impressionistic not aiming to the philologists. We hope that this does not pose a problem to the interested historians of medicine.

Challenges of Political Parties in the Appointment of Public Positions

Political parties face several challenges when appointing public positions, the importance lies in the need to guarantee efficiency, transparency and legitimacy, in public management it is the selection of suitable and qualified candidates to occupy positions of responsibility in the government. In one context, citizens demand greater professionalism and ethics in public service, ensuring that their candidates have the skills to perform their duties efficiently. At the same time, it is about promoting inclusion and diversity in the appointment of public positions, ensuring the participation of all sectors of society. This means promoting the inclusion of women, young people, indigenous peoples, as well as people with special abilities and groups that have been relegated for many years. This will contribute to strengthening institutions and improving the quality of public management, responding to the demands of increasingly demanding citizens.

Identify and mitigate bias in electronic phenotyping: A comprehensive study from computational perspective

Electronic phenotyping is a fundamental task that identifies the special group of patients, which plays an important role in precision medicine in the era of digital health. Phenotyping provides real-world evidence for other related biomedical research and clinical tasks, e.g., disease diagnosis, drug development, and clinical trials, etc. With the development of electronic health records, the performance of electronic phenotyping has been significantly boosted by advanced machine learning techniques. In the healthcare domain, precision and fairness are both essential aspects that should be taken into consideration. However, most related efforts are put into designing phenotyping models with higher accuracy. Few attention is put on the fairness perspective of phenotyping. The neglection of bias in phenotyping leads to subgroups of patients being underrepresented which will further affect the following healthcare activities such as patient recruitment in clinical trials. In this work, we are motivated to bridge this gap through a comprehensive experimental study to identify the bias existing in electronic phenotyping models and evaluate the widely-used debiasing methods’ performance on these models. We choose pneumonia and sepsis as our phenotyping target diseases. We benchmark 9 kinds of electronic phenotyping methods spanning from rule-based to data-driven methods. Meanwhile, we evaluate the performance of the 5 bias mitigation strategies covering pre-processing, in-processing, and post-processing. Through the extensive experiments, we summarize several insightful findings from the bias identified in the phenotyping and key points of the bias mitigation strategies in phenotyping.

Correlation between Muscle Mass and Physical Activity Level in Older Adults at Risk of Falling: The FITNESS Study

BackgroundThe study investigates the correlation between muscle mass and physical activity level measured objectively and subjectively in older adults who fall or are at high risk of falling.MethodsFITNESS (Fall Interest to Target Newly Sarcopenic Society) is a multi-center (French university hospitals of Angers, Lille, Limoges and Orléans), cross-sectional, observational study of routine care within a French multidisciplinary hospital consultation. Inclusion criteria were ≥ 75 years old, living at home and consulting for fall or gait disorder. A standardized geriatric assessment, muscle mass evaluation by impedancemetry, physical activity by continuous actimetry (5 days) and Incidental and Planned Exercise Questionnaire (IPEQ) were performed at patient inclusion.Results170 people aged 75 and over were included in the FITNESS study (mean age 82.9 ± 4.7 years, women 72.9%). Muscle mass (whole body and lower limbs) correlated with active energy expenditure (AEE, ρ whole body = 0.32, p-value < 0.001; ρ lower limbs = 0.25, p-value = 0.003), but not with number of daily steps, nor with IPEQ score. Multivariate analysis of whole-body muscle mass showed a positive and significant association with AEE and albumin levels and for lower limb muscle mass, a positive association with AEE and Charlson.ConclusionThis study suggests that in the particular population of older adults who fall and/or are at high risk of falling, loss of muscle mass correlates with reduced physical activity. So subjects who fall or at high risk of falling constitute a special group for whom the fight against sedentary lifestyles and the maintenance of physical activity should be a dual priority.

Play as Occupation: The State of Our Science and a Research Agenda for the Profession.

Occupational therapists view play through a unique lens. Considering play as a human occupation, and one to which all people have a right, places occupational therapists among a special group of professionals championing play. This State of the Science article seeks to increase awareness regarding the occupational therapy profession's contributions and to situate those contributions within the larger body of literature on play while also promoting further study of play as an occupation.

Invariant measures on p-adic Lie groups: the p-adic quaternion algebra and the Haar integral on the p-adic rotation groups

We provide a general expression of the Haar measure—that is, the essentially unique translation-invariant measure—on a p-adic Lie group. We then argue that this measure can be regarded as the measure naturally induced by the invariant volume form on the group, as it happens for a standard Lie group over the reals. As an important application, we next consider the problem of determining the Haar measure on the p-adic special orthogonal groups in dimension two, three and four (for every prime number p). In particular, the Haar measure on SO(2,Qp)\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$\ ext {SO}(2,\\mathbb {Q}_p)$$\\end{document} is obtained by a direct application of our general formula. As for SO(3,Qp)\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$\ ext {SO}(3,\\mathbb {Q}_p)$$\\end{document} and SO(4,Qp)\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$\ ext {SO}(4,\\mathbb {Q}_p)$$\\end{document}, instead, we show that Haar integrals on these two groups can conveniently be lifted to Haar integrals on certain p-adic Lie groups from which the special orthogonal groups are obtained as quotients. This construction involves a suitable quaternion algebra over the field Qp\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$\\mathbb {Q}_p$$\\end{document} and is reminiscent of the quaternionic realization of the real rotation groups. Our results should pave the way to the development of harmonic analysis on the p-adic special orthogonal groups, with potential applications in p-adic quantum mechanics and in the recently proposed p-adic quantum information theory.

Assessment of wound cultures in an oncology hospital

Purpose: The aim of this study is to evaluate the patient's demographic, clinical and laboratory data to determine whether the bacteria isolated from wound cultures are causative agents or colonization, and to determine their antimicrobial susceptibilities. Materials and methods: This research was conducted in XXXX between January 1, 2021 and December 31, 2022. Two hundred thirty six isolates from 186 patients wound cultures were included in the study. Demographic data, clinical data and laboratory results of the patients were evaluated. The isolated bacteria and their antimicrobial susceptibilities were determined. The Q score system was used to evaluate the microbiological quality of wound samples. Results: One hundred fifty nine cases (85%) were inpatients. Totally 119 (63.9%) patients were diagnosed with infection. The Q score for 136 samples (85.5%) was assessed as Q3. The most common isolated microorganisms were coagulase negative-staphylococci (CoNS) (19%), E.coli (14.8%), and S.aureus (13.1%), respectively in wound bacterial cultures. The methicillin resistance rate was 55.5% in CoNS and 54.1% in S.aureus. Gram-negative bacteria were isolated in 81 (59.9%) infected patients. Among the infected patients, 39 (32.7%) patients had surgical site infections, 25 (21%) prosthesis infections, and diabetic foot infections 3 (2.5%). Infection rates were statistically significantly higher in patients with surgery, prosthesis, and diabetic foot (p=0.054). Conclusion: In conclusion, Q score is a strong marker in diagnosing wound infection and excluding colonization and helps prevent unnecessary antibiotic use. Local antibiotic susceptibility data should be examined up-to-date in the empirical treatment of special patient groups such as oncological patients.

The negative spillover effect of sandwich-generation caregiving on employees’ job satisfaction: does work time matter?

PurposeThis study aims to investigate the effect of sandwich-generation caregiving (caregiving for elders and children simultaneously) on employed caregivers’ job satisfaction when compared with non-sandwich caregiving patterns of no caregiving, children-only caregiving and elders-only caregiving. This study also aims to explore whether depression mediates this effect and whether three types of caregivers-friendly work time (less work-time length, less nonstandard work-time schedule and more work-time autonomy) buffer these direct and indirect effects.Design/methodology/approachA sample of 7,571 Chinese employees is chosen from the 2020 China Family Panel Studies through a multistage stratified sampling design.FindingsAfter controlling for employees’ sociodemographic, work and other caregiving characteristics, this study finds that sandwich-generation caregiving is indeed more likely to negatively affect employees’ job satisfaction when compared with no caregiving and elders-only caregiving, but to the same extent as children-only caregiving. This study also suggests that the effect of sandwich-generation caregiving on job satisfaction is mediated by employees’ depression and that three types of caregiver-friendly work time help to weaken the negative effects on employees’ depression and job satisfaction.Originality/valueTo the best of the authors’ knowledge, this is the first study to explore the negative spillover effect and its mechanisms of caregiving on employees’ job satisfaction through focusing on a special caregivers group: employed sandwich-generation caregivers. These results shed light on the importance of extending caregiver studies to the workplace and provide implications for organization managers and human resources practitioners to design caregiver-friendly workplace policies to maintain employed caregivers’ work-family balance.