Spearman Rank Correlation Test Research Articles

Comparison of the vitality test with sensitivity tests in mature and immature teeth: clinical trial.

One of the most important steps in deciding on the treatment of a tooth is to determine the vitality and health status of the pulp. Since immature teeth innervation is not completed, the response to sensitivity tests may not yield definite results. Pulse oximetry (PO) which is considered as a vitality test, measures the arterial oxygen saturation (SpO2). This study aims to compare PO, electric pulp test (EPT) and cold test in mature and immature permanent teeth. 20 immature and 20 mature permanent incisors of 6-12-year-old ASA1 children who did not use any analgesics, were included in the study. Pulp vitality of the teeth was determined by EPT, cold test and PO. An infant probe of PO device (CMS60D, Contec Medical Systems Co. Ltd, China) was used to determine the SpO2 of the teeth. The SpO2 level is controlled on the patient's finger by a children's probe and an infant probe of PO. Shapiro-Wilk, Spearman rank correlation test and Kruskal-Wallis test/Dunn post-hoc analysis were used for statistical comparisons. There was no significant correlation between finger SpO2 and the mature/immature teeth SpO2 (r=-0.026, r = 0.253). Arterial oxygen saturation values in the immature teeth were significantly higher than in the mature teeth (p = 0.002). There was a high correlation between the vitality response of the EPT, cold test and PO. Pulse oximetry can be used as an effective vitality test compared to sensitivity tests in both immature and mature permanent incisors.

Relationship between Femoral Proximal Bone Quality Assessment by MRI IDEAL-IQ Sequence and Body Mass Index in Elderly Men.

Bone assessment using the MRI DEAL-IQ sequence may have the potential to serve as a substitute for evaluating bone strength by quantifying the bone marrow hematopoietic region (R2*) and marrow adiposity (proton density fat fraction: PDFF). Higher body mass index (BMI) is associated with increased bone mineral density (BMD) in the proximal femur; however, the relationship between BMI and R2* or PDFF remains unclear. Herein, we investigated the correlation between BMI and MRI IDEAL-IQ based R2* or PDFF of the proximal femur. A retrospective single-cohort study was conducted on 217 patients diagnosed with non-metastatic prostate cancer between September 2019 and December 2022 who underwent MRI. The correlation between BMI and R2* or PDFF of the proximal femur was analyzed using Spearman's rank correlation test. Among 217 patients (median age, 74 years; median BMI, 23.8 kg/m2), there was a significant positive correlation between BMI and R2* at the right and left proximal femur (r = 0.2686, p < 0.0001; r = 0.2755, p < 0.0001, respectively). Furthermore, BMI and PDFF showed a significant negative correlation (r = -0.239, p = 0.0004; r = -0.2212, p = 0.001, respectively). In elderly men, the increased loading on the proximal femur due to elevated BMI was observed to promote a decrease in bone marrow adiposity in the proximal femur, causing a tendency for a transition from fatty marrow to red marrow with hematopoietic activity. These results indicate that the MRI IDEAL-IQ sequence may be valuable for assessing bone quality deterioration in the proximal femur.

Application of family nursing documentation in Tarakan City, Indonesia

Documentation of nursing care is authentic proof of nursing service activities, serving as the basis for fulfilling nurses' responsibilities and accountabilities. Family nursing documentation holds distinct characteristics compared to other nursing practice settings. The Indonesian nursing professional organization has established three standards for nursing care: diagnosis, intervention, and outcome. This research aimed to understand how the implementation of family nursing care documentation is conducted by community nurses in Tarakan City. The research was a correlational study with a cross-sectional approach. The study population consisted of all the nurses working in Community Health Centers in Tarakan City, totaling 80 individuals. The sample was selected using total sampling. The research variables included demographic factors, nurses' knowledge about the documentation concept, and the application of family nursing documentation; these were measured using a modified researcher-made questionnaire and declared valid and reliable. The analysis of research data used descriptive analysis and the Spearman Rank correlation test. This research identified that the majority of community nurses in Tarakan City did not implement family nursing documentation, and the level of knowledge regarding nursing documentation concepts was low. The Spearman's rank correlation test yielded a p-value of 0.874, indicating no significant correlation between the level of knowledge and the implementation of family nursing documentation. The inhibiting factors for the implementation of family nursing care documentation primarily included a high workload, a limited number of health center nurses, motivation, and the lack of clear and uniform documentation guidelines.

Eco-Gender Gap Dalam Pemeliharaan Lingkungan di Desa Wisata (Kasus : Rumah Tangga Anggota Komunitas Pecinta Lingkungan di Desa Wisata Batulayang, Kecamatan Cisarua, Kabupaten Bogor)

Batulayang Tourism Village is one of West Java Province's sustainable tourism villages. Gender equality in environmental preservation are an important factor in efforts to preserve the ecological environment. Men and women share equal responsibility for environmental preservation. The purpose of this study is to examine the relationship between environmental preservation and the level of the gender gap. This study uses a mixed method exploratory sequential design approach, applying in-depth interviews for qualitative followed by questionnaires for quantitative data collection. The respondents in this research are 30 household members of the environmental community and 5 people research subjects who were in Ecovillage Program. The Spearman Rank Correlation and Chi-Square Test were utilised in this data processing for quantitative data. The research findings indicate that the Ecovillage Programe has sufficiently increased community participation to care more about the surrounding environment; however, in its implementation in the household sphere, the lack of gender-based environmental awareness causes there to still be a gap between husbands and wives in environmental management because environmental management is often associated with women's domestic role.

Analysis of Dominant Risk Factors for Stroke Incidence and Unhealthy Lifestyle at Sidomulyo Pekanbaru Health Center

The introduction of health in the community is not only seen in the health sector but also must be seen in all sectors that influence health problems. Generally, there are two kinds of causes of stroke. The first is a blockage of the arteries, called ischemic stroke, while the second cause is rupture of blood vessels, or stroke ischemic, while the second cause is a rupture of blood vessels called a hemorrhagic stroke. Other causes of stroke can be a temporary disruption of blood flow to the brain, commonly referred to as an ischemic attack (TIA). These three conditions have a series of potential factors that trigger stroke. Hemorrhagic. Other causes of stroke can be a temporary disruption of blood flow to the brain, commonly referred to as an ischemic attack (TIA). These three conditions have a series of potential factors that trigger stroke. The study employed the Spearman rank correlation test method to investigate the relationship between smoking habits, alcohol consumption, lack of physical activity, and the occurrence of stroke. It involved 41 respondents from the Sidomulyo Health Center's jurisdiction. The findings revealed a significant association between smoking habits and stroke, as indicated by a significance value of 0.007, which is less than the threshold of 0.05. Similarly, there was a significant relationship observed between alcohol consumption and stroke, with a significance value of 0.016. However, the analysis showed no significant correlation between lack of physical activity and stroke, as the significance value of 0.446 exceeded the threshold of 0.05.

A BWM-TOPSIS Linear Programming Model for Evaluating the Performance of Health-Promoting Hospitals with McKinsey 7s Framework in Organizational Management

This research addresses the critical aspect of evaluating operational performance in health promotion hospitals, which play a vital role in providing medical services to local communities. The research proposes an integrated method for performance assessment, utilizing the Best-Worst Method (BWM) and the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) linear programming model. Taking the case of health promotion hospitals in Maha Sarakham province, Thailand, and considering the McKinsey 7s framework's seven criteria, BWM is employed to determine the criteria weights. Subsequently, the TOPSIS linear programming model selects the ideal health promotion hospital based on these weights. The BWM analysis reveals criteria weights in the following order: system, staff, skill, style, structure, strategy, and shared value. The TOPSIS linear programming model identifies SH12 as the top-performing health promotion hospital with a closeness coefficient value of 0.8821. Additionally, a Spearman's rank correlation test validates this proposed method against the original TOPSIS approach, yielding a correlation value of 1.0. These findings provide valuable guidance for organizations, particularly in shaping strategic policies and resource allocation within medical service units, medical equipment, and personnel management in organizational settings. This study offers that the proposed method is simpler and will aid in the ongoing analysis of strengths and weaknesses in the improvement of organizations and development, helping organizations adapt to changes.

The Effectiveness of Discharge Planning Implementation on the Quality of Life of Post Opname Patients with Heart Failure at Hospital

Background: Heart failure is a disease with a high rehospitalization rate due to patients not fulfilling recommended therapy, for example, breaking a diet, doing excessive physical activity and lack of understanding during discharge planning. This causes a decrease in the quality of life after patient is discharged. Purpose: This research aims to determine the effectiveness of discharge planning implemention on the quality of life of post-opname patients with heart failure at Bhayangkara Hospital, Kediri City. Method: The type of research used is quantitative research with a descriptive cross-sectional study design. The number of samples in this study were 31 respondents with accidental sampling technique. Results: The results of the non-parametric Spearman rank correlation test analysis obtained a value of p = 0.022 (p &lt;0.05) and a correlation coefficient of 0.411 which is moderate and has a positive direction. This shows that there is a positive relationship between the effectiveness of implementing Discharge Planning on the quality of life of post-hospitalized patients with heart failure at Bhayangkara Hospital, Kediri City. Conclusion: Discharge Planning given to patients with heart failure at Bhayangkara Hospital, Kediri City is not yet effective and needs to be improved. However, the majority of respondents have a good quality of life where respondents experience an increase in socialization, psychology, but still experience physical discomfort.

Differences in Glutamate Dehydrogenase (GLDH) and Other Liver Biochemistry Levels before and after Remdesivir Treatment in COVID-19

Background: Remdesivir (RDV) is a broad-spectrum antiviral approved by the Food and Drug Administration (FDA) for the treatment of Covid-19 patients, known to have the potential to cause toxic effects on the liver. Routine monitoring of liver biochemical parameters such as AST, ALT, bilirubin, ALP and GGT, can help detect liver injury. Drug-induced liver injury, according to Hy's law, is characterized by an increase in ALT &gt; 5x ULN, or ALP &gt; 2x ULN, or an increase in ALT &gt; 3x and total bilirubin &gt; 2x ULN, simultaneously. Glutamate dehydrogenase (GLDH) is a sensitive and specific hepatic marker, which can detect liver injury and loss of mitochondrial integrity earlier than other liver biochemical parameters. This study aimed to analyze GLDH levels and liver biochemical parameters before and after RDV therapy in patients with Covid-19. We also analyze several factors that affect liver function and suggest renal function. Methods: This study used an observational analytical with a prospective cohort design, in a population of Covid-19 patients receiving RDV therapy at the infectious emergency department and isolation ward Dr. Soetomo Surabaya for September-November. Consecutive sampling was taken. The subject had drawn blood twice; once before therapy and 5 days after receiving intravenous RDV. GLDH examination is using sandwich ELISA method, while ALT, AST, ALP, GGT, direct and total bilirubin were determined spectrophotometrically. Mann-whitney, the Wilcoxon rank test and Spearman correlation test were used to analyze the data. Results: The number of samples was 34 participants with an average age of 52.47+15.21 years. Concomitant medications were dominated by n-acetylcysteine (94.1%), antioxidants (91.2%) and immunomodulators (82.4%). None of the subjects suffered liver injury induced by RDV according to Hy’s Law. Median GLDH serum levels before RDV treatment 1,14 U/L and after 5 days RDV administration 0,85 U/L (p=0,945), AST (36,4 U/L; 34, 00U/L; p=0,140), ALT (30,43 U/L; 30,20 U/L; p=0,301), DBI (0,15mg/dL; 0,24mg/dL; p=0,090), TBI (0,49mg/dL; 0,50mg/dL; p=0,567), ALP (85,0U/L; 87, 5 U/L; p=0,313) dan GGT (64,5U/L; 71,0U/L; p=0,871). The use of concomitant medication was thought to have protective properties against hepatocytes. Conclusion: After 5 days of RDV treatment, there is no evidence of liver injury. There are no significant differences in GLDH levels and other liver biomarker parameters compared to baseline. There is no difference in delta GLDH levels between groups with and without renal impairment.

Relationships between self-efficacy, health belief, and self-care among type 2 diabetes mellitus

Introduction: Diabetes mellitus (DM) patients need to be empowered to manage their conditions. Some factors that affected the empowerment of diabetes mellitus patients were self-efficacy, health beliefs, and self-care. Self-efficacy positively correlates with health belief and self-care among patients with type 2 DM. However, such evidence is still limited in the Health Care Centers, especially in Yogyakarta. This research aimed to identify self-efficacy and the relationship between health belief and self-care among Type 2 DM patients. Methods: This is a correlative analytical of quantitative research using the cross-sectional approach. Purposive sampling was used to collect the samples, which were 83 patients who belonged to the inclusion criteria. This research was conducted in the Primary Health Center in Bantul Yogyakarta between April and May. The statistical tests used the Spearman rank correlation test due to the abnormal distribution. Results: The mean of self-efficacy, health belief, and self-care were 84.9±9.3; 105,1±7,2; 67,8±7,7, respectively. There was a significant relationship between self-efficacy and health belief at the value of p&lt;0.000, and there was a relationship between self-efficacy and self-care at the value of p&lt;0.000. Conclusion: Positive correlations were achieved between self-efficacy and health belief and between self-efficacy and self-care in diabetes mellitus patients.

The Relationship of Physical Activity, Energy, and Protein Intake with Nutritional Status in Adolescents at Junior High School

Indonesia is still in a nutritional emergency. Undernutrition or overnutrition is a health problem that is often found in adolescence. Nutritional problems that occur are influenced by an imbalance between physical activity and macronutrient intake in adolescents. This study aims to determine the relationship between physical activity, energy intake, and protein intake with nutritional status in adolescent girls. Observational study with a cross-sectional approach conducted in July – August 2023 at Junior High School 2 Long Bagun, Mahakam Ulu Regency, East Kalimantan. A total of 42 adolescents were included as samples based on purposive sampling by setting inclusion and exclusion criteria. Physical activity variables were measured in the International Physical Activity Questioner (IPAQ) while energy and protein intake were obtained through a 24-hour food recall form. The BMI / U formula measures nutritional status-data analysis using the Spearman Rank correlation test. Our findings show the majority of adolescents with moderate physical activity (76.2%), adequate energy intake (66.7%), and adequate protein intake (66.6%). The results of the relationship analysis showed physical activity (p = 0.001, r = 0.512), energy intake (p = 0.001, r = 0.503), protein intake (p = 0.002, r = 0.459) with the nutritional status of adolescents at Junior High School 2 Long Bagun. There is a significant relationship between physical activity, energy intake, and protein intake with the nutritional status of adolescents at Junior High School 2 Long Bagun. These findings are empirical evidence for the formation of better adolescent health programs

Impact of environmental factors on Biomphalaria pfeifferi vector capacity leading to human infection by Schistosoma mansoni in two regions of western Côte d'Ivoire

AbstractBackgroundIntestinal schistosomiasis remains a worrying health problem, particularly in western Côte d'Ivoire, despite control efforts. It is therefore necessary to understand all the factors involved in the development of the disease, including biotic and abiotic factors. The aim of this study was to examine the factors that could support the maintenance of the intermediate host and its vectorial capacity in western Côte d'Ivoire.MethodsData on river physicochemical, microbiological, and climatic parameters, the presence or absence of snails with Schistosoma mansoni, and human infections were collected between January 2020 and February 2021. Spearman rank correlation tests, Mann–Whitney, analysis of variance (ANOVA), and an appropriate model selection procedure were used to analyze the data.ResultsThe overall prevalence of infected snails was 56.05%, with infection reaching 100% in some collection sites and localities. Of 26 sites examined, 25 contained thermophilic coliforms and 22 contained Escherichia coli. Biomphalaria pfeifferi was observed in environments with lower land surface temperature (LST) and higher relative air humidity (RAH), and B. pfeifferi infection predominated in more acidic environments. Thermal coliforms and E. coli preferred higher pH levels. Lower maximum LST (LST_Max) and higher RAH and minimum LST (LST_Min) were favorable to E. coli, and lower LST_Max favored coliforms. The presence of B. pfeifferi was positively influenced by water temperature (T °C), LST_Min, RAH, and precipitation (Pp) (P < 0.05) and negatively influenced by pH, total dissolved solids (TDS), electrical conductivity (EC), LST_Max, and mean land surface temperature (LST). The parameters pH, TDS, EC, LST_Min, LST, and Pp had a positive impact on snail infection, while LST_Max had a negative impact on infection. Only pH had a positive effect on coliform and E. coli abundance. Of the 701 people examined for human schistosomiasis, 73.13% were positive for the point-of-care circulating cathodic antigen (POC-CCA) test and 12.01% for the Kato–Katz (KK) test. A positive correlation was established between human infections and the abundance of Biomphalaria (r2 = 0.879, P = 0.04959).ConclusionsThe results obtained reflect the environmental conditions that are conducive to the maintenance of S. mansoni infection in this part of the country. To combat this infection as effectively as possible, it will be necessary not only to redouble efforts but also to prioritize control according to the level of endemicity at the village level.Graphical

The Relationship between Long Time Undergoing Hemodialysis and Stress Levels in Chronic Kidney Failure Patients Undergoing Hemodialysis at Bendan Regional Hospital, Pekalongan City

Chronic renal failure is characterised by irreversible decline in kidney function. Chronic renal failure requires haemodialysis therapy. Long time undergoing haemodialysis can cause psychological problems such as stress. The purpose of this study was to assess the relationship between length of haemodialysis and stress level in chronic renal failure patients undergoing haemodialysis at Bendan Hospital, Pekalongan City. Methods: The research design used descriptive correlative with cross sectional approach. The study population were all chronic renal failure patients undergoing haemodialysis at Bendan Hospital, Pekalongan City, as many as 70 people. The study sample were 70 patients with chronic renal failure who underwent haemodialysis at Bendan Hospital, Pekalongan City by total sampling. The research instruments were questionnaires and Perceived Stress Scale (PSS). Data analysis used spearman rank correlation test. Results: the majority of respondents, 36 people (51,4%) had undergone haemodialysis for ≤ 1 year and the majority of respondents, 58 people (82.9%) experienced moderate stress. The results showed that there was relationship between the length of undergoing haemodialysis with stress levels in chronic renal failure patients undergoing haemodialysis at Bendan Hospital, Pekalongan City with a ρ value: 0,000 with a correlation value of rho of -0,438, which means that the length of haemodialysis has a moderate strength of relationship with stress levels. Conclusion: length of haemodialysis is associated with stress levels of chronic kidney failure patients

Do Patients With Mental Illness Undergoing Office-Based Sedation Require an Increased Propofol Dosage?

Providers report needing higher sedative doses to achieve adequate sedation in patients with mental illnesses. These claims, however, have not been thoroughly assessed. The purpose of the study was to measure the association between mental illness and the propofol dosage necessary to achieve a satisfactory level of anesthesia. The study consisted of a single-center, retrospective cohort consisting of patients treated by oral and maxillofacial surgery at the University of Cincinnati Medical Center in 2020. The study was comprised of subjects 15 or older who were American Society of Anesthesiologists (ASA) classification I or II. Subjects under 15 or ASA III or higher were excluded from the study. The predictor variable was the presence or absence of mental illness. The primary outcome was the total dose of propofol, measured as the total amount of propofol administered divided by the patient's weight in kilograms divided by the length of the procedure in minutes (mg/kg/min). The secondary outcome was the Richmond Agitation-Sedation Scale (RASS) score achieved during sedation. Sex, race, ethnicity, age, weight, body mass index, ASA score, prior tobacco use, marijuana use, use of adjunct midazolam, fentanyl, and ketamine during the procedure, and type of procedure served as covariates. Test statistics were calculated using the Wilcoxon rank-sum test, Kruskal-Wallis test, Spearman rank correlation test, and χ2 test for bivariate analyses. Linear and logistic regression models were used to estimate association while controlling for confounding. P values ≤ .05 were considered statistically significant. The study sample was 409 subjects (36.92% male, mean age 28.27±12.20years). In bivariate analysis, mental illness did not show any association with propofol dose (mean dose with mental illness 150.85±143.97mg/kg/min, mean dose without mental illness 116.54±104.16, P=.08) or RASS score (sufficiently sedated with mental illness 63.38%, sufficiently sedated without mental illness 58.80%, P=.36). After adjusting for all previously mentioned covariates, mental illness was statistically associated with propofol dose (P<.01). Adjusting for covariates, only sex had a statistically significant association with the RASS score (P<.05). The findings suggest that a patient's mental illness may influence the amount of sedative required to achieve satisfactory anesthesia.

Buprenorphine prescribing and treatment accessibility in response to regulation changes due to the COVID-19 public health emergency

BackgroundIn 2021, over 80,000 fatal overdoses occurred in the United States. Since 2020, the federal government has enacted multiple regulatory changes around buprenorphine prescribing for opioid use disorder (OUD) to increase access to buprenorphine. This study aims to explore trends in buprenorphine treatment initiation pre- and post-public health emergency to evaluate changes in the context of X-waiver relaxations and telehealth allowances. MethodsIn a cross-sectional study, all RI residents who filled a buprenorphine prescription at a pharmacy in Rhode Island (RI), Massachusetts, and Connecticut between January 2017 and December 2023 were obtained from the RI Prescription Drug Monitoring Program (PDMP). The study excluded buprenorphine products not approved for OUD treatment from the analysis. Identified individuals had initiated buprenorphine for OUD during the study period if they did not have a prior prescription or if they had >30 days without buprenorphine exposure between their prescriptions. Spearman's rank correlation tests were used to identify significant associations between outcomes and regulation changes. ResultsThe average number of patients dispensed buprenorphine did not significantly change over the study period, however the average number of initiates significantly decreased (ρ = −0.38255, p = .0003). The average number of providers prescribing CII-CV substances in RI has increased 3.4 % over the study period. The average percentage of prescribers in the PDMP prescribing buprenorphine for OUD doubled (ρ = 0.96075, p < .0001). ConclusionThough efforts have been made to increase buprenorphine initiation, buprenorphine initiates remain well below pre-PHE levels. Efforts must continue to eliminate existing barriers to treatment and improve access to individuals seeking treatment.

Hubungan Tingkat Pengetahuan Tentang Vaksinasi Terhadap Kesediaan Vaksinasi Booster COVID-19 Pada Radiografer di Wilayah Jember

Radiographers are at high risk of being infected with COVID-19 related to the most common transmission of COVID-19, so radiographers must be vaccinated. Antibody levels from primary vaccine can only last for 12 to 20 weeks, so booster vaccine is needed. Booster vaccination is one of health behaviors that divided into three domains: cognitive (knowledge), affective (attitudes), and psychomotor (actions). Based on the background above, the authors are interested in researching the relationship between knowledge level about vaccination and willingness to be vaccinated COVID-19 booster among radiographers at Jember. This type of research is a correlational analytic survey with a cross-sectional approach. Population in this research were all radiographers who are members of the Indonesian Radiographers Association (PARI) and active in Jember. The sampling method using total sampling (n=60). Data analysis in this research included editing, scoring, coding, tabulating, univariate analysis, normality test, and bivariate analysis (Rank Spearman Correlation Test) using IBM SPSS Statistics 25 software. Respondent's knowledge level about vaccination showed 46% good, 27% moderate, and 27% less. Respondent’s willingness to be vaccinated COVID-19 booster showed 47% good, 43% moderate, and 10% less. Rank Spearman Correlation Test (Spearman Rho) showed p value or Sig. (2- tailed) of 0.001 and correlation coefficient was 0.43 (+). There is a significant relationship between knowledge level and willingness to be vaccinated COVID-19 booster among radiographers at Jember with moderate correlation strength and unidirectional correlation.

Analysis of Therapy Satisfaction on the Quality-of-Life of Type 2 Diabetes Mellitus Patients at Anutapura Hospital Palu

Background: Type 2 Diabetes Mellitus (Type 2 DM) is a chronic disease characterized by increased blood glucose levels caused by impaired insulin function. In Palu City, Type 2 DM is the 2nd most common in Central Sulawesi with a total of 26,204 people. Objective: This study aims to determine the relationship between therapy satisfaction and the quality of life of Type 2 DM patients who perform outpatient treatment at Anutapura General Hospital, Palu. Methods: With a random sample approach, 100 respondents were used in this cross-sectional study that employed an observational method. Data collection used instruments in the form of a DMSAT (Diabetes Medication Satisfaction Tool) therapy satisfaction questionnaire and a DQOL (Diabetes Quality Of Life) quality of life questionnaire. Results: The results of the study were obtained on therapy satisfaction from Type 2 DM patients with the number of respondents in the very satisfied (1.0%), satisfied (90.0%), and quite satisfied (9.0%) categories while the results of the study of the quality of life of Type 2 DM patients 2 fall into the good category (38.0%), and the bad category (62.0%). The statistical analysis test used was the Spearman Rank Correlation test. The results of the Spearman Rank Correlation test value p = 0.037 or p &lt;α (0.05), then H0 is rejected, which means that there is a relationship between satisfaction with therapy and quality of life in patients with Type 2 DM which is very weak. Conclusion: The conclusion in this study is that there is a very weak relationship between therapy satisfaction and quality of life of patients.

Hubungan Self-Esteem Remaja Awal Dengan Perilaku Kesehatan Gigi dan Mulut (Studi Pada Pelajar SMP di Kecamatan Karangpucung)

Self-esteem was a psychological aspect that not only affects mental heath, but also has an important contribution to physical health. Self-esteem was thought to be an aspect that affects early adolescents during puberty, impact on health behavior, one of them was oral health behavior. The aim of this research to determine the relationship between early adolescent self-esteem and oral health behavior in junior high school students in Karangpucung DistrictThis was an analytic observational study with a cross-sectional design. The research sample was 315 junior high school students in Karangpucung District with convenience sampling. Instrument in this study used a Rosenberg Self-Esteem Scale (RSES) and oral health behavior questionnaire. The Spearman Rank correlation test used to determine the relationship between early adolescent self-esteem and oral health behavior in junior high school students in Karangpucung District. There was a significant relationship between adolescent self-esteem and oral health behavior toward positive, weak correlation strength (p=0,004, r=0,163). There was a relationship between early adolescent self-esteem and oral health behavior in junior high school students in Karangpucung District, namely students who have high self-esteem characteristics tend to have oral health behavior in the moderate category.

Perceptions of HIV-AIDS and motivation for HIV testing among Balinese tourist village community

The right perception of HIV-AIDS by the community of tourist villages can lead to the motivation to identify their HIV status. A tourist village has zero case of HIV-AIDS will have a positive impact on the health conditions of the tourist village community and increase in tourist visits. This study aims to determine the correlation between HIV-AIDS perceptions and the motivation for HIV testing in the tourist village community of Sayan Ubud, Bali. Descriptive correlation design with a cross-sectional approach was used in this study. The sample size was 353 respondents who were taken by proportionate random sampling. Spearman rank correlation test was used for data analysis. The result showed a correlated HIV-AIDS perception and HIV testing motivation (p=0.000; r=0.611). A better perception of HIV-AIDS leads to increased HIV testing motivation in the community. This study can be used as basic data in the preventive programme of new HIV cases through HIV testing services. Thus, the Sayan Ubud tourist village community can identify their HIV status without any negative stigma.

Correlation of circulating fibroblast growth factor 21 levels with inflammatory factors and the degree of coronary artery stenosis in patients with acute myocardial infarction

BackgroundFibroblast growth factor 21 (FGF21) is a secreted protein that plays an important role in atherosclerosis and pathological cardiac remodeling. However, the correlation between FGF21 and the degree of coronary artery stenosis and its potential role in acute myocardial infarction (AMI) remain unclear. We examined whether changes in FGF21 levels in AMI correlate with the degree of coronary artery stenosis and the levels of inflammatory factors, and preliminarily investigated the effects of FGF21 on inflammatory factor levels and myocardial injury in rats with AMI. MethodsSerum levels of FGF21 and inflammatory factors in the AMI group and control group were measured, and the correlation between FGF21 and clinical indicators and inflammatory factors was analyzed. The effects of FGF21 on cardiac function and inflammatory response were evaluated through echocardiography and measurement of inflammatory factors. ResultsMultivariate logistic regression analysis showed that neutrophil percentage (NEUT%, odds ratio [OR]: 1.232; 95 % confidence interval [CI]: 1.028–1.477; p = 0.024) and FGF21 levels (OR: 2.063; 95 % CI: 1.187–3.586; p = 0.01) had independent effects on AMI. Spearman's rank correlation test showed that FGF21 levels were positively correlated with leukocyte count, NEUT%, neutrophil count, neutrophil to lymphocyte ratio, C-reactive protein, interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), monocyte chemotactic protein-1 (MCP-1) and Gensini scores (p < 0.01), but negatively correlated with lymphocyte count (p < 0.01). FGF21 levels in myocardial tissues and serum levels of FGF21, IL-6, TNF-a, and MCP-1 were significantly higher in AMI rats than in the sham-operated group (p < 0.01). After overexpression of FGF21, serum levels of IL-6, TNF-a, and MCP-1 in rats were significantly decreased (p < 0.01), and cardiac function improved significantly. ConclusionsFGF21 levels were independently associated with AMI and may be related to the severity of coronary artery stenosis. Overexpression of FGF21 reduced serum inflammatory factor levels and improved cardiac function in AMI rats.

От неалкогольной к метаболически ассоциированной жировой болезни печени. Стеатометрия и кардиометаболические факторы как предикторы развития стеатогепатита

Non-alcoholic metabolic dysfunction-associated fatty liver disease is the most common liver sickness linked with the high risk of hepatic and extrahepatic complications. The article provides an overview of changes in the nomenclature of this disease, analysis of risk factors for its development and the results of own research. The aim of the study was to estimate the clinical significance of steatometry (CAP function) by Fibroscan and cardiometabolic factors in assessing the risk of steatohepatitis development. Material and methods. Patients with hepatic steatosis accompanied by metabolic disorders were examined. Steatometry as well as routine physical and laboratory examination, including biochemical blood tests and abdominal ultrasound were provided. Statistical analysis included χ2 test, Spearman's rank correlation test, Student's t-test, Mann–Whitney test, multiple linear regression analysis. Results. 74 patients were included. Main characteristics of the cohort: 62.2% male, mean age – 48.8 years, cases of steatohepatitis – 41.9%. It was revealed that the number of metabolic factors in an individual patient correlated with the presence of steatohepatitis (χ2 = 3.29; p &lt; 0.05) and the severity of steatosis by steatometry (rs = 0.37; p &lt; 0.05). Individual clinical and laboratory parameters influenced the severity of steatosis with varying degrees. The most significant parameters were: abdominal circumference, concentration of HDL, insulin, activity of ALT, GGTP, and the presence of arterial hypertension. Using these indicators, a formula for assessing the risk of severe liver steatosis was created. Conclusion. Steatometry is to be considered as an important diagnostic method for the prognosis assessment in patients who have risk factors for the development and progression of non-alcoholic metabolic dysfunction-associated fatty liver disease. Severe steatosis is a predictor of steatohepatitis. The number of metabolic factors present in an individual patient is important in assessing the risk of severe liver steatosis and steatohepatitis.