Spearman Rank Correlation Test Research Articles

Persepsi Petani Terhadap Inovasi Kopi Robusta Organik di Kabupaten Lampung Barat

Perceptions play a crucial role in the adoption of innovation, particularly in the context of organic farming practices. This study aimed to explore farmer perceptions and factors influencing their perceptions of organic coffee innovation in Robusta coffee cultivation in West Lampung Regency. The research was conducted from December 2022 to January 2023, with a sample of 59 respondents from three farmer groups: Ampera, Langgeng Mulyo, and Margo Rahayu. Using a questionnaire and non-parametric statistical analysis, including the Rank Spearman correlation test, the study found significant relationships between farmer knowledge, availability of capital, social interaction, and marketing with their perceptions of organic coffee innovation. However, land area, length of farming, and selling price did not show significant relationships. These findings highlight the importance of enhancing farmer knowledge and providing adequate capital support, facilitating social interactions, and improving marketing strategies to promote the adoption of organic Robusta coffee cultivation. The government's attention to market development and pricing mechanisms for organic Robusta coffee can further incentivize farmers to engage in this sustainable agricultural practice.

Comparison of intelligibility measures for children with velopharyngeal insufficiency: visual analog scale ratings, interval scales, and orthographic transcription (OT)-based measures

ABSTRACT Regardless of the underlying cause for speech impairment in speakers with cleft palate, a universal consequence of cleft palate is reduced speech intelligibility. Still, there is no standardised approach for measuring intelligibility for speakers with cleft speech. The current study aimed to determine the relationship between orthographic transcription (OT)-based measures, interval-scale ratings, and visual analog scale (VAS) ratings for perceptual judgements of intelligibility in speakers with cleft palate as judged by speech-language pathologists (SLPs). The speaker participants were six speakers with velopharyngeal insufficiency secondary to cleft palate. Four sets of sentences from the Hearing in Noise Test were recorded from each speaker. A total of 14 SLPs provided their intelligibility judgement on these speaker’s recordings by word-by-word orthographic transcriptions, a visual analog scale (0–100), and a 5-point interval rating scale. A Spearman rank correlation test indicated a negative, strong correlation between OT-based measurements and VAS scores (r = −.94; p = 0.01) and between OT-based measurements and interval rating scores (r = −.77, p = 0.01). A strong, positive correlation was found between scores obtained from VAS and interval rating scales (r = .83, p = 0.05). The strong relationship between the objective measure of intelligibility (i.e. OT-based measure) and a subjective measure of intelligibility (i.e. VAS and interval scale) supports using a less time-consuming VAS as a substitute for orthographic transcription in measuring intelligibility in cleft palate speech.

Peer Support and Anti-retroviral (ARV) Medication Adherence Among People Living with HIV/AIDS: A Cross-Sectional Study

One of the supports that People Living with HIV/AIDS (PLWHA) can provide each other is the encouragement to take medicine. Medication adherence and not resisting therapy are very important for PLWHA to maintain their immune system, suppress viral replication, and improve quality of life. This study aimed to determine whether there was a relationship between peer support and anti-retroviral (ARV) medication adherence among people living with HIV/AIDS (PLWHA). . The study was conducted in August 2020. The research design used was a correlational study using a cross-sectional approach. The sampling technique used was total sampling. The respondents in this study were PLWHA who are at Cahaya Kasih Peduli AIDS Foundation, WPA Turen n = 45. The variables studied were peer support as the independent variable and medication adherence as the dependent variable. The data collection technique used was a questionnaireThe data analysis method used was the Spearman Rank correlation test using SPSS 25 with a significance of p <0.05. From this study, it was found that 20 (44.4%) for good peer support, 25 (55.6%) for sufficient peer support 13 (28.9%) had high adherence to taking medication, 15 (33.3%) had moderate adherence, and 17 (37.8%) had low adherence. The results of statistical tests in this study showed no significant relationship between peer support and medication adherence to People Living with HIV/AIDS at Cahaya Kasih Peduli AIDS Foundation, WPA Turen, with a significance value of p-value = 0.313. It was found that there is no relation between peer support and medication adherence to PLWHA at the Cahaya Kasih Peduli AIDS Foundation, Turen. Respondents are always expected to pay attention to their medication schedule and be more active in socializing and providing mutual support to fellow PLWHA.
 Keywords: Peer Support, Medication Adherence, People Living with HIV / AIDS (PLWHA)

Cloud type frequency over Poland (2003–2021) revealed by independent satellite‐based (MODIS) and surface‐based (SYNOP) observations

AbstractRecent studies have identified several statistically significant trends in cloud genera frequency over Poland. Notably, there has been an increase in high and convective clouds, along with a decrease in Stratus, Altostratus and Nimbostratus. These earlier studies were, however, only based on traditional, surface data. As the ability to observe mid and high‐level clouds from the ground is limited, due to overlapping, we address the question of whether these trends are confirmed by other sources of cloud data, such as satellite records. In this paper, we analyse cloud data from two fully independent sources to characterize the cloud type climatology over Poland for the period 2003–2021: cloud optical thickness (COT) and cloud top pressure (CTP) parameters retrieved from Moderate Resolution Imaging Spectroradiometer (MODIS), and surface (SYNOP) observations of cloud genera from the country's 27 ground‐based stations. The International Satellite Cloud Climatology Project (ISCCP) COT–CTP classification was used to define MODIS cloud types. We explore the hypothesis that MODIS data, classified using the ISCCP philosophy, confirms the changes in cloud type frequencies found in SYNOP observations. Our analysis is based on the application of the Spearman rank correlation test to mean monthly SYNOP and MODIS cloud type frequencies, and we compare per decade trends for two time series. Our hypothesis was confirmed, but only for Cirrus, Altostratus + Nimbostratus and Cumulus. We therefore conclude that the two analysed data sources are not fully consistent, and cannot substitute for each other in cloud type climatologies. Hence, at least for Poland, they should be treated as independent rather than complementary. We also demonstrate that the increase in high‐level cloud frequency over Poland, which has been observed by other authors who based their research on synoptic data, is not due to a decrease in the frequency of low‐ and mid‐level clouds. Our findings are confirmed by satellite records.

The correlation between spiritual coping with the lifestyle of hypertension patients in Ploso Kuning village

Introduction: The lifestyle of patients with hypertension is an important factor in treating hypertension, but in fact, the lifestyle of patients with hypertension is still quite bad. A bad lifestyle triggers complications and increases the prevalence of hypertension. The purpose of the study was to analyze the relationship between spiritual coping and the lifestyle of hypertension sufferers. Methods: The research method uses observational analytics, the independent variable is spiritual coping, the dependent variable is the lifestyle of people with hypertension, and the sampling technique uses simple random sampling. The sampled population is all hypertension sufferers in Ploso Kuning village who are between 26 to 65 years old, can read and are willing to be respondents. The sampling technique used is simple random sampling with a sample size of 108 respondents. Data analysis using Spearman rank correlation test. Results: The results showed that spiritual coping had a significant effect on the lifestyle of hypertension sufferers with a p-value of 0.000. Conclusion: The lifestyle of patients with hypertension can be improved by increasing the spiritual coping of the sufferer.

Husband's Support Relationship with Elderly Wife's Depression Level

Depression in the elderly is a mental disorder experienced by individuals aged 60 years and over, including feelings of sadness, anxiety, difficulty sleeping and desperation. Depression in wives who are entering old age is a serious mental health problem. Most elderly does not know the symptoms of depression, and it make it difficult for them to adjust to the stressors. The husband is the main source of support for the wife in maintaining her health. The purpose of this study was to determine the correlation between husband's support and the incidence of depression wife among elderlies. This research was an analytic descriptive correlation study with a cross sectional approach. The research sample is 40 wives chosen by purposive sampling with inclusion criteria: 60-90 years old; still had husbands; lived with their husbands; experiencing depression. The research instruments were the Geriatric Depression Scale (GDS) questionnaire and the husband support questionnaire developed by the researchers. The data analysis using Spearman Rank correlation test. The results showed that 22 respondents (55%) had sufficient support from husband; 17 respondents (42.5%) experienced mild depression, and there was a correlation between husband support and the wife's depression level (p-value=0.000) and the value of the correlation coefficient (r)=-0.648. It is suggested that community nurses and cadres for elderlies involve the husbands to provide support for their wives to prevent depression

The unfolding mystery of the numbers: First and second digits based comparative tests and its application to Ghana’s elections

This study focuses on the use of digits-based test in anomaly detection in presidential elections in Ghana. Even though Ghana has conducted several successful elections to elect presidents, the outcomes of the elections have been challenged in courts on allegations of vote rigging and fraud. It has been established in the literature that for an election to be anomaly free, the following should be satisfied: the distribution of voters turn-out, the winners’ share and total valid votes cast in the election should be uni-modal. Therefore, we assess the applicability of both first and second digits-based tests to aid in the detection of possible anomaly in the 2016 and 2020 presidential election results data in Ghana. The Benford frequency distribution and Spearman rank correlation coefficient tests were used for the analysis of data obtained from the Electoral Commission of Ghana. The results show that the observed first digits distributions of valid vote counts for both New Patriotic Party (NPP) and National Democratic Congress (NDC), and the total valid votes cast (TVVC), in 2016 and 2020 are consistent with the distributional pattern of first digits postulated by Benford’s Law. However, the findings of the distribution of second digits of the valid vote counts for NPP and total valid vote cast in both 2016 and 2020 elections do not satisfy the probability distributional pattern of second digits according to the Benford’s Law. In view of these, we recommend using the first two digits-based tests to check for consistency of possible election anomaly between the first and second digits since it conveys more information.

Correlation and Community Stability Analysis of Herbaceous Plants in Dashiwei Tiankeng Group, China

Studying the interspecific association and stability of herbaceous communities in different developmental stages of tiankeng is helpful to understand the relationship between tiankeng vegetation and the environment, and can provide an important theoretical basis for the protection and restoration of the karst tiankeng ecosystem. In this study, the herbaceous community of the Dashiwei Tiankeng Group in Guangxi was studied to analyze the interspecific relationships and community stability of herbaceous plants in four different habitats (the earlier stage, middle stage, late stage and the external forest of tiankeng), and to explore whether the herbaceous community structure gradually stabilized with the development of tiankeng. The variance ratio (VR), X2 test, association coefficient (JI) and the Spearman rank correlation coefficient test were used to analyze the interspecific association of the main herbaceous plants in different developmental stages of tiankeng. The stability of the herbaceous community was analyzed by the stability measurement method of M. Godron. The results showed that: (1) the logarithm of the middle stage of tiankeng negatively correlated species was the highest (56.7%), and the logarithm of the later stage of tiankeng positively correlated species was the highest (57.2%). The positive and negative correlation ratio of main herbs decreased first and then increased, indicating that the middle stage of development was the period of high competition among herbs and the biggest difference in resource utilization. The ecological habits of herbaceous plants will be changed from sciophiles to hygrophytes to heliophiles and drought-enduring plants. (2) The earlier stage and middle stage of tiankeng overall relevance had a significant negative correlation, the later stage and external forest of tiankeng overall correlation were not significant positive correlation, and the X2 test and the Spearman rank correlation coefficient of different developmental stages of tiankeng most major herbaceous species were not significant correlation, suggesting that the major herbs in tiankengs had weak association and strong independence. (3) The distance from the intersection point to the stable point (20, 80) was 19.799, 17.867, 18.922 and 17.706, respectively, of the four regression models of tiankengs herb community, which further indicated that the forest herb layers were in an unstable state. The forest outside is relatively more stable than the herbaceous community inside the tiankeng.

The relationship between the PICC tip position and weight gain, length growth of premature infants under ultrasonography: a correlation analysis study.

This study aimed to analyze the correlation between PICC tip position and weight/length changes in preterm infants in different positions using ultrasonography. The study is a prospective before and after self-control clinical trial. The study analyzed the distance between the PICC tip and the entrance of the heart under ultrasonography for premature infants who underwent PICC insertion. The infants were positioned and tracked weekly, and their weight and length were recorded. The Spearman rank correlation test was used to analyze the relationship between the displacement distance of the PICC tip under ultrasonography in different positions and weight/length changes. A total of 202 premature infants were included in the study, and 100% of them experienced changes in the PICC tip position. During the first week, 134 (66.33%) cases in a flexed position and 153 (75.74%) cases in a straight position showed displacement of the catheter toward the heart. The displacement distance of the tip during catheter retention was significantly correlated with weight change (rs = 0.681/0.661, P < 0.05) and length change (rs = 0.629/0.617, P < 0.05). In the third and fifth weeks, weight increased by 451 ± 178 and 750 (715-975) g, length increased by 1.50 (1.00-2.12) and 3.00 (2.00-3.70) cm, the catheter moved 1.27 ± 0.89 and 2.23 ± 0.95 cm, respectively, in a flexed position. The PICC tip position in preterm infants is influenced by weight and length changes. It is crucial to use ultrasonography to track and locate the catheter within the first week of placement and to increase the frequency of catheter localization starting from the third and fifth weeks. The flexed position is recommended during catheter localization.

#4547 IDENTIFICATION OF GLYCOSYLATED IGF2 IN HUMAN URINARY PEPTIDOME AND ITS ASSOCIATION WITH CKD

Abstract Background and Aims Chronic kidney disease (CKD) is prevalent in 10% of world's adult population, with estimated glomerular filtration rate (eGFR) and albuminuria employed in its diagnosis. Role of protein glycosylation in causal mechanisms of CKD progression is largely unknown. Aim of this study was to identify urinary O-linked glycopeptides in association to CKD for better characterization of CKD molecular manifestations. Method Urine samples from eight CKD and two healthy subjects were analyzed by Capillary Electrophoresis-Tandem Mass Spectroscopy (CE-MS/MS) and glycopeptide analysis using Proteome Discoverer 1.4 was performed. Distribution of identified glycopeptides and correlation with Age, eGFR and Albuminuria were evaluated in 3810 datasets from the Human Urinary Proteome database using Spearman's rank correlation test and multiple linear regression analysis by statistical software R. The quantification of Insulin-like growth factor-II (IGF2) protein (7.5 kDa) was performed by enzyme-linked immunosorbent assay (ELISA) in two matched (for age, sex, no diabetes and no cardiovascular history) groups of 12 plasma samples each (eGFR &amp;lt; 30 ml/min/1.73m2 and eGFR &amp;gt; 90 ml/min/1.73m2). An open-source tool “Proteasix” was used to predict proteases involved in cleavage of the identified glycopeptides. The transcriptomics database and analysis tool “Nephroseq v4” were utilized to investigate the expression of predicted proteases in existing human transcriptomics CKD datasets. Results In total, 17 O-linked glycopeptides from 7 different proteins were identified, derived primarily from Insulin-like growth factor-II (IGF2) (n = 6). Glycosylation occurred at the surface exposed IGF2 Threonine 96 position. Further Investigation of the human proteome database containing 3810 datasets, showed that only three unglycosylated urinary peptides of IGF2 were identified, at significantly lower abundance and frequency (0-2.5% in the database) in comparison to the glycosylated forms (frequency of 23-90%). Interestingly, all identified IGF2 peptides belonged to E-domain of IGF2, i.e., 92 – 180 aa; which cleaves after undergoing O-linked glycosylation during the post-translational process yielding the “mature IGF2” (25-91 aa) protein. Results of multiple linear regression analysisa indicated that three IGF2 glycopeptides, DVStPPTVLPDNFPRYPVGKF [β(1024) = 0.08, p = 1.42*10−4], DVStPPTVLPDNFPRYPVG [β(560) = 0.01, p = 5.22*10−5] and DVStPPTVLPDNFPRYP [β(290) = 0.02, p = 1.07*10−4], exhibited positive correlation with Age and the glycopeptide tPPTVLPDNFPRYP showed strong negative association with eGFR [β(177) = -0.01, p = 4.21*10−9]. Along the same lines, the latter urinary IGF2 glycopeptide tPPTVLPDNFPRYP was found at increased [p &amp;lt; 2.2*10−16] abundance in CKD (n = 686) in comparison to healthy control (n = 229) datasets. In addition, IGF2 increased [p = 0.042] plasma levels were observed in CKD patients (eGFR &amp;lt; 30 ml/min/1.73m2 group) as supported by ELISA measurements. Protease predictions, considering also available transcriptomics data, suggest activation of cathepsin S with CKD potentially involved in the cleavage of the CKD-associated glycopeptide of IGF2. Conclusion Collectively, this study indicates that with aging and deteriorating kidney function, alterations in IGF2 proteoforms take place; which may be reflective of respective changes in the mature IGF2 protein abundance and function; as well as associated protease activity. Further, correlation analyses of the levels of the CKD-associated urinary IGF2 glycopeptide with the plasma IGF2 levels with CKD progression is planned. a Results of multiple linear regression where regression Co-efficient is β; degree of freedom is stated in (brackets); and p-value &amp;lt;0.05 was considered statistically significant

Hubungan Religious Coping dengan Resiliensi pada Pasien Stroke di Wilayah Kerja Puskesmas Purwokerto Selatan

Stroke is a disease condition caused by a sudden cessation of blood flow to the brain, either due to blockage or rupture of blood vessels and is the third most common non-communicable disease after hypertension and diabetes. Stroke has a psychological impact that causes the patient to be irresistible. Resilience affects the recovery process in stroke patients. Stroke sufferers who are not resilient are influenced by religious coping (spirituality) where spiritual strength and belief can increase resilience in individuals. The purpose of this study was to determine the relationship between religious coping and resilience in stroke patients in the Work Area of the South Purwokerto Public Health Center. Research design is correlation study survey with a cross sectional time approach. The sample of this research was 45 respondents using simple random sampling technique. Data analysis was determined by the spearman-rank test. The results showed that religious coping in stroke patients in the Work Area of the South Purwokerto Health Center was mostly positive (84.4%). The resilience of stroke patients in the Work Area of the South Purwokerto Health Center is mostly high (86.7%). The results of the Spearman rank correlation test showed that the p-value was 0.0001 (p-value &lt; 0,05). The conclusion is that there is a correlation between Religious coping and Resilience in Stroke patients in work area at South Purwokerto Health Center.

Hope therapy: Can it treat hopelessness and internal locus of control on diabetes mellitus patients?

Patients with diabetes mellitus (DM) are always required to be able to control a healthy lifestyle throughout their life to avoid various diseases that can accompany the previous illness. However, psychological factors in the form of despair due to lack of hope make people with diabetes more depressed and less able to control behavior and maintain blood sugar stability, so an excellent internal locus of control is needed to be stronger. This study aimed to determine the effect of hope therapy in reducing hopelessness and increasing internal locus of control in people with DM. The research design used a experimental study with ten randomly selected respondents divided into two groups, namely the control group and the experimental group. Data retrieval using the locus of control scale and the beck hopelessness scale. Data analysis used non-parametric analysis, namely the Mann Whitney test, Wilcoxon test, and Spearman's Rank Correlation test. The results of the Mann-Whitney U test on the internal locus of control variable show a value of 0.000 and a p score of 0.008 (p <0.05), it can be concluded that there are differences in the internal locus of control in the experimental group compared to the internal locus of control in the control group. The hopelessness variable shows a value of 0.000 and a p score of 0.008 (p <0.05), this indicates that there is a difference in hopelessness in the experimental group and the control group. There is a decrease in hopelessness and an increase in internal locus of control in people with DM given hope therapy.

Subclinical retinopathy in systemic lupus erythematosus patients - optical coherence tomography study.

The aim was to detect subclinical structural retinal abnormalities in optical coherence tomography (OCT) in ophthalmologically asymptomatic systemic lupus erythematosus (SLE) patients without signs of lupus retinopathy or drug toxicity in fundus examination and in OCT and to assess the relationship between OCT parameters and disease activity, therapy type and burden on other organs to demonstrate the utility of OCT in early retinal impairment in SLE patients. Cross-sectional study. Thirty-three SLE patients (57 eyes) and 31 healthy individuals (56 eyes) were enrolled in the study. We excluded patients with evidence of lupus retinopathy or hydroxychloroquine (HCQ) toxicity on OCT or fundus examination to reveal any subclinical changes. All patients underwent full ophthalmologic examination in the slit lamp including best corrected visual acuity, tonometry, and OCT. The Kolmogorov-Smirnov distribution test was used to assess the normal distribution in quantitative values. The differences between the individual measured parameters in the groups were analyzed using the Mann-Whitney U test. Spearman's rank correlation test was used to assess the correlation between the measured parameters and quantitative clinical data. There was no difference in the OCT findings between SLE and healthy control groups. Among the study group a negative correlation was found between disease duration and age and retinal nerve fiber layer thickness in the inferior quadrant (p = 0.0063, p = 0.0036). No correlations were observed between examined retinal parameters and duration of hydroxychloroquine therapy, hydroxychloroquine as well as chloroquine cumulative dose and disease activity indices. Optical coherence tomography is a widespread ophthalmic modality used for SLE retinopathy and HCQ toxicity screening. Our study did not demonstrate its clinical potency in diagnosis of subclinical retinal involvement. An optical coherence tomography device seems to be less sensitive in subclinical retinal impairment detection than optical coherence tomography angiography.

Pharmacy Students' Perceptions of Remote versus Face-to-Face Learning Experience.

During the COVID-19 pandemic, there was a large shift from face-to-face (FTF) to remote learning. Evaluating students' perceptions of remote learning provides educators with opportunity to inform their instructional methods. This study sought to evaluate pharmacy students' self-perceived (1) confidence, (2) preparedness, (3) satisfaction, and (4) motivation following remote vs. FTF classes. An electronic survey was distributed to six pharmacy student cohorts enrolled in the University of Findlay College of Pharmacy during April 2021 to measure the objectives. The Kruskal-Wallis, Mann-Whitney U, and Spearman's rank correlation tests were used to analyze the data (alpha = 0.05). A total of 151 students completed the survey. While the responses differed among the cohorts, first-professional year students reported lower motivation to study (p = 0.008), engage (p = 0.008), satisfaction with content presentation (p = 0.05), preparedness for exams (p < 0.001), and confidence to communicate (p = 0.008) and succeed in a career (p < 0.001) when studying remotely vs. taking FTF classes compared to fourth-professional year students. Positive correlations were observed between students who felt motivated to engage and study (ρ = 0.501, p < 0.001), motivated to study and exam preparedness (ρ = 0.511, p < 0.001), satisfied with course material presentation and professor accessibility (ρ = 0.688, p < 0.001), and exam preparedness (ρ = 0.521, p < 0.001), and felt prepared for exams and able to succeed in a pharmacy career (ρ = 0.573, p < 0.001). Taking the above results into consideration, pharmacy educators may designate more time and instructional support to first-professional year students in an effort to improve students' perceptions of motivation, satisfaction, confidence, and preparedness.

The relationship between inflammatory biomarkers and macular pigment optical density in hypertensive patients: a cross-sectional study.

Inflammation may be associated with macular pigment optical density (MPOD) degradation. The relationship between inflammation and MPOD is evaluated using inflammatory biomarkers, including high sensitivity C-reactive protein (hsCRP), lipid level and ratio, waist circumference (WC), and body mass index (BMI). In this cross-sectional design, 62 hypertensive patients were recruited between January 6 and January 8, 2022, at a primary care unit. The MPOD was measured using the Macular pigment screener II. Blood tests for hsCRP, lipid profile, WC measurement, BMI calculation, and completing a questionnaire were conducted, and statistical analysis was done by using Microsoft Excel 2019 and Stata version 16.1. Spearman's rank correlation test was used to evaluate correlations. Multivariate analysis for adjusting confounders was done by logistic regression. There was a significant negative correlation between hsCRP >3 and MPOD (r = -0.26, P = 0.04). Inflammation was linked to MPOD. Anti-inflammatory agents may be beneficial in preventing MPOD degradation.

Cranial Vault Suture Obliteration in Relation to Age: An Autopsy-Based Observational Study.

Age is one of the most critical identifiers for both living and dead. Forensic professionals in medical and legal matters are often presented with dismembered, disfigured, putrefied, or skeletal remains for analysis. In such situations, it is essential to identify individuals and estimate their ages. The skull is typically thewell-preserved part of the body in such situations. If an aged person needs their age officially established for employment, superannuation, pension settlements, senior citizen benefits, etc., they may turn to medical professionals for help in making that determination. It has always been controversial to use cranial suture obliteration as a reference for age. Different geographicallocations have been shown to have vastly different patterns of cranial suture closure. Therefore, this study was conceptualized to assess cranial vault sutureobliteration in relation to age in the Meo population. This study was conducted to determine whether obliteration of cranial sutures can be taken into account for the estimation of age in elderly in this region and its reliability along with the influence of other factors such as sexand right and left side differences. A total of 100 cases of more than 20 years of age brought for medicolegal autopsy were analyzed. The coronal, sagittal, and lambdoid sutures were studied ectocranially and endocranially. The degree of obliteration of sutures was scored ectocranially as well as endocranially. Data were analyzed using IBMSPSSStatistics for Windows, Version 21 (Released 2012; IBM Corp., Armonk, New York, United States). Descriptive statistics were evaluated for continuous data in terms of mean and standard deviation, and categorical data were presented by frequency and percentages. An independent t-test was applied to find out the mean difference between the right and left sides of suture closure for ectocranial and endocranial surfaces. The Spearman rank correlation test was carried out to find out the relationship between the age and score of suture closure both ectocranially and endocranially. Ectocranially and endocranially, the overall sagittal suture obliterates early followed by coronal sutures and then lambdoid sutures. On comparing the mean ectocranial and mean endocranial scores of 100 subjects by applying an independent t-test, a highly significant difference was observed in all three sutures. On correlating ectocranial sutures and endocranial sutures and age at death in all the cases through sagittal, right and left coronal, and lambdoid by applying the Spearman rank correlation coefficient, a highly significant correlation was found in all the subjects combined (p-value 0.000). However, no significant correlation (p-value >0.05) was found in ectocranial and endocranial sagittal sutures in individual age groups. We concluded that obliteration on the endocranial surface is more reliable than on the ectocranial surface. No statistically significant difference exists on the obliteration of sutures on the right and left sides of coronal and lambdoid sutures. The lapsed union was evident in all three sutures ectocranially. Endocranial suture obliteration can be used as a corroborative tool for age estimation.

THE RELATIONSHIP BETWEEN FAMILY INCOME AND THE NUTRITIONAL STATUS OF PREGNANT MOTHERS AT AMPEL 1 PRIMARY HEALTH CARE CENTER IN BOYOLALI REGENCY

Pregnancy represents a significant phase in the lives of women, particularly for those who are married. Thus, pregnancy necessitates specialized attention, especially concerning the fulfillment of energy and nutritional requirements. The quality of maternal dietary intake before and during pregnancy has the potential to influence the health of both the mother and her baby. Malnutrition during pregnancy can lead to various complications, affecting both the mother and the fetus, including issues like anemia, bleeding, and inadequate maternal weight gain. Maternal nutritional intake is influenced by a multitude of internal and external factors within the pregnant mother and her family, encompassing factors such as low levels of knowledge, social dynamics, and household income. This study aims to explore the correlation between the nutritional status of pregnant women and the family income level at the Ampel Health Center in Boyolali Regency. The research employs a quantitative approach utilizing an analytical survey method with a cross-sectional design. The study involved a sample size of 30 pregnant women. The results reveal that the majority of participants are aged between 20-35 years, predominantly in the second trimester of pregnancy, with 10 respondents (33.3%) in trimester II and 20 respondents (66.6%) in trimester III. The Spearman's rank correlation test yielded a p-value of 0.353, which is above the significance level of 0.05 (0.353 &gt; 0.05). Nonetheless, there is no significant correlation between the nutritional status of pregnant women and the family income level at the Ampel Health Center in Boyolali Regency.

Vitreous Humor Biomarkers Reflect Pathological Changes in the Brain for Alzheimer's Disease and Chronic Traumatic Encephalopathy.

Patients with eye disease have an increased risk for developing neurodegenerative disease. Neurodegenerative proteins can be measured in the eye; however, correlations between biomarker levels in eye fluid and neuropathological diagnoses have not been established. This exploratory, retrospective study examined vitreous humor from 41 postmortem eyes and brain tissue with neuropathological diagnoses of Alzheimer's disease (AD, n = 7), chronic traumatic encephalopathy (CTE, n = 15), both AD + CTE (n = 10), and without significant neuropathology (controls, n = 9). Protein biomarkers i.e., amyloid-β (Aβ40,42), total tau (tTau), phosphorylated tau (pTau181,231), neurofilament light chain (NfL), and eotaxin-1 were quantitatively measured by immunoassay. Non-parametric tests were used to compare vitreous biomarker levels between groups. Spearman's rank correlation tests were used to correlate biomarker levels in vitreous and cortical tissue. The level of significance was set to α= 0.10. In pairwise comparisons, tTau levels were significantly increased in AD and CTE groups versus controls (p = 0.08 for both) as well as AD versus AD+CTE group and CTE versus AD+CTE group (p = 0.049 for both). Vitreous NfL levels were significantly increased in low CTE (Stage I/II) versus no CTE (p = 0.096) and in low CTE versus high CTE stage (p = 0.03). Vitreous and cortical tissue levels of pTau 231 (p = 0.02, r = 0.38) and t-Tau (p = 0.04, r = -0.34) were significantly correlated. The postmortem vitreous humor biomarker levels significantly correlate with AD and CTE pathology in corresponding brains, while vitreous NfL was correlated with the CTE staging. This exploratory study indicates that biomarkers in the vitreous humor may serve as a proxy for neuropathological disease.

HIPERTENSI, AKTIVITAS FISIK, INDEKS MASSA TUBUH (IMT) DENGAN KADAR GULA DARAH PADA PASIEN DIABETES MELITUS DI BULELENG

Diabetes Mellitus and Hypertension is a common condition that often arises together, both diseases are considered as the risk of cardiovascular disease and microvascular complications of many factors that influence it like bad lifestyle changes. This study aims to determine the relationship between hypertension, physical activity, and body mass index with blood sugar levels in Diabetes Mellitus patients at Public Health Center in Buleleng. This research uses a quantitative research design cross-sectional method with a simple random sampling technique with 150 samples, taken by observation, and observation is guided by the Baecke questionnaire. Data analysis with Spearman Rank correlation test shows no relationship between hypertension with blood sugar levels with value ρ = (0.938)&gt; α (0.05), no relationship between physical activity with blood sugar level body mass index with blood sugar level with value ρ = (0.914)&gt; α (0.05). There is no relationship between hypertension, physical activity, and body mass index with blood sugar levels in Diabetes Mellitus patients

The Effect of Nanosilver Sodium Fluoride on the Mechanical and Physiochemical Properties of Artificially Demineralised Dentin.

To synthesise and characterise nanosilver sodium fluoride (NSSF) and assess the effect of applying this formulation in vitro on artificially demineralised root dentin lesions, compared with the application of silver diamine fluoride (SDF), sodium fluoride (NAF) or no treatment, in terms of mechanical, chemical and ultrastructural properties. NSSF was prepared using 0.5 wt% chitosan solution. On 40 extracted human molars, the buccal aspect of the cervical thirds of roots were prepared and divided into 4 groups of 10 each: control (no treatment), NSSF, SDF and NaF (n = 10). The specimens were examined using scanning electron microscopy (SEM), atomic force microscopy (AFM), and x-ray photoelectron spectroscopy (XPS). Fourier transform infrared spectroscopy (FTIR), surface and cross-sectional microhardness and nano-indentation tests were performed to determine the mineral and carbonate content, microhardness, and nanohardness, respectively. Statistical analysis was performed to determine the differences between the different treatment groups for the set parameters using parametric and non-parametric tests. Tukey's and Dunnet's T3 post-hoc tests were further used for multiple comparisons between groups (α = 0.05). The control group (no treatment) was found to have statistically significantly lower mean scores for surface and cross-sectional microhardness compared with all other test groups (NaF, NSSF and SDF) (p < 0.05). Spearman's rank correlation test showed statistically insignificant differences between the mineral-to-matrix ratio (M:M) and carbonate content of all groups (p < 0.05). Treatment of root lesions with NSSF yielded comparable results to SDF and NaF under in-vitro conditions.