Since the 20th century, urbanization has been the main characteristic of global land development. If we can reveal and understand the characteristics and underlying mechanisms of urban development, we can then identify a sustainable development pattern for cities. In this paper, we primarily focus on the determinants of two main types of land use in urban development, industrial and commercial, in an empirical study of Beijing. We use a spatial data analysis method to seek and model major determinants of industrial and commercial land growth in the period of 2000–2010 in Beijing. A spatial logistic regression model is used to explore the impact of spatial independent variables on these two types of land use. The study shows that: (1) newly-added industrial land during 2000–2010 received significant contributions from the number of local enterprises engaged in services in 2010, the use of land for agriculture and construction in the neighborhood in 2000 and planning orders; (2) factors contributing to land transferred for commercial use included the number of enterprises, construction land in the neighborhood and accessibility improvement.