Span Style Research Articles

Genetic Polymorphisms and Risk of Cardiovascular Disease

<p><span style="font-size: 10.0pt; font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-fareast-font-family: PMingLiU; mso-hansi-theme-font: minor-bidi; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: EN-US;">Cardiovascular disease (CVD) is the major cause of death and disability worldwide. Major and well-established cardiovascular disease risk factors include advancing age, male sex, hypertension, smoking, diabetes, elevated total serum low-density lipoprotein (LDL) cholesterol, and decreased high-density lipoprotein (HDL) cholesterol. Genetic polymorphism represents an additional risk factor for cardiovascular disease and is not explored and researched thoroughly. In this review article, a total of 31 scientific articles studying the association between different genetic polymorphisms and the risk of cardiovascular disease were studied. <a name="_Hlk80393453"></a>Different genetic polymorphisms were found to be associated with an increased risk of cardiovascular disease and coronary heart disease incidence, and genotyping of these different genetic polymorphisms should be considered as routine screening for cardiovascular disease.</span></p>

WHY DID PEOPLE ARGUE ON TWITTER? SCRUTINIZING ARGUMENTATION STRATEGIES USED IN THE TWEETS OF #InternationalWomensDay

<span style="font-size: 10.0pt; font-family: 'Cambria','serif'; mso-ascii-theme-font: major-latin; mso-fareast-font-family: 'Times New Roman'; mso-hansi-theme-font: major-latin; mso-bidi-font-family: 'Times New Roman'; color: #0e101a; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;">The phenomenon reflected in the tweets used in #InternationalWomensDay as the campaign has provided many people to argue freely on social media platform. Giving an argumentation will conceal the hidden problems spread in the society. Several public problems will be left without any attention. Therefore, this study aims to scrutinize argumentation strategies used by Twitter users in tweets using the #InternationalWomensDay using the Critical Discourse Analysis approach. This present research employs argumentation strategies theory proposed by Teun A. Van Dijk (2000) as well. The data were collected from the tweets using #InternationalWomensDay. In addition, the descriptions of the data were displayed qualitatively. Overall, the results reveal that from the data analysis, the number game strategies became the most frequently used strategy in tweets using the #InternationalWomensDay and the fewest strategy used in this hashtag was pseudo-ignorance. In summary, every tweet made on Twitter using a particular hashtag tends to have a certain purpose.</span>

APLIKASI SISTEM LAYANAN PEMESANAN JASA DESAIN DAN APLIKASI BERBASIS ABDROID PADA PT. PUTRA WISANGGENI SATU MENGGUNAKAN METODE WATERFALL

<p align="justify"><span style="font-size: 11.0pt; line-height: 115%; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman'; mso-fareast-theme-font: minor-fareast; mso-bidi-font-family: Arial; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;" lang="EN-US">PT. Putra Wisanggeni Satu is a company that is active in the field of digital platforms, business and trade consultants in the company. Almost all service ordering activities use WhatsApp messenger. revisions are in demand and vulnerable to conversation data being lost or accidentally deleted. The aim of this research is to design and build an Android-based application for ordering design services and applications to improve service quality and make it easier to order services more efficiently. This research involves several steps, including problem analysis, data collection, application design and development and application testing. At the data collection stage, it was carried out using interview and observation methods and for the system development method using the waterfall method. At the application testing stage, the blackbox testing method shows that almost all features are implemented successfully and function properly as well as the results of usability testing, on the Effectiveness aspect of 94.2%, Efficiency aspect of 0.163 goals / Sec with an overall relative efficiency value of 83.3%. And for the satisfaction aspect of 78.5 . The results of this study indicate that the application can view service price lists, place service orders, service revisions and pay by bank transfer method.</span></p>

The effectiveness of the european central bank in pursuing its prime mandate

<p class="MsoNormal" style="margin-top: 12pt; text-align: justify;"><span lang="EN-US" style="font-family: arial, helvetica, sans-serif;">The objectives and tasks of the European Central Bank (ECB) are defined in Articles 2 and 3 of Protocol (No 4) on the Statute of the European System of Central Banks (ESCB) and of the European Central Bank (ECB). While in Article 3,1° of this Protocol other tasks are mentioned, the prime objective of the ESCB and therefore of the ECB, is price stability. This concept was originally specified by the Executive Board of the ECB as an annual increase of less than 2% in the inflation rate over the medium term, measured by the Harmonized Index of Consumer Prices (HICP) for the euro area. This paper examines to what extent the ECB has been effective in realizing price stability over the period from January 1, 2000 to December 31, 2022. Price stability is important for economic agents. It allows them to plan their savings, spending and investment eventually resulting in sustained economic growth.<span style="mso-spacerun: yes;">   </span>Notwithstanding the commitment of large human and other resources and the use of unconventional monetary policies, the ECB did not realize its prime objective during a large part of this period. We conclude that putting too much confidence in DSGE-modeling as one of the methodologies to determine monetary policy, may have played an important role in the ECB not achieving its main statutory objective.</span></p>

Progress, Evolving Paradigms and Recent Trends in Economic Analysis

<p class="MsoNormal" style="margin-top: 12pt; line-height: 14pt; text-align: justify;"><span lang="EN-US" style="font-family: arial, helvetica, sans-serif;">This paper provides a thorough review of the shifting landscape of economic analysis, spotlighting recent trends and predicting future paths. While traditional economic models remain key for interpreting economic activity, they are being supplemented by fresh methods and cross-disciplinary viewpoints. The increased attention to inequality studies, using advanced statistical techniques and unique data sources, underscores the growing emphasis on fairness and distribution within economic analysis. The incorporation of behavioral elements into economic models also expands our comprehension of economic decision-making and market results. Notably, the emergence of computational economics-integrating artificial intelligence (AI), big data, and machine learning into economic scrutiny-represents a major development. Often referred to as ’smart economics,’ this field employs technology to formulate, address complex economic dilemmas, and perceive economic activity in unconventional ways. Yet, the application of AI and machine learning in economics introduces new hurdles around data privacy, algorithmic bias, and the transparency of model outcomes. The impact of the digital revolution on economic analysis is significant, as the advent of computational economics and the surge of big data are transforming research techniques and policy implications. Concurrently, the advent of the circular economy indicates a radical shift in our perspective on economic sustainability, carrying considerable implications for environmental policy and business tactics.<span style="mso-spacerun: yes;">  </span>In the future, it’s anticipated that these trends will further modify the realm of economic analysis, with AI and machine learning integration, emphasis on sustainability and fairness, and the influence of big data becoming more pronounced. As these changes take place, it’s imperative for researchers, policymakers, and practitioners to remain adaptable and flexible, prepared to capitalize on the opportunities and tackle the challenges these trends present.</span></p>

Impact of third-party online payment systems on trade, export, import, and internet retailing

<p style="text-align: justify;"><span style="font-family: 'times new roman', times, serif; font-size: 14pt;">This study estimates the impact of third-party online payment systems on trade, export, import, and Internet retailing in China. Also, the study examines the financial development mechanism via which third-party payment affects trade, export, import, and Internet retailing in China. By employing a sample of 31 provinces in China covering 2011 to 2018, the findings indicate that, third-party payment drives China’s trade (0.43%), export (0.42%), import (0.47%), and Internet retailing (0.24%). The study also finds that third-party payment complements financial development to positively affect trade, export, import, and Internet retailing in China. The study recommends policymakers promote third-party payment development in China to boost trade, export, import, and Internet retailing.</span></p>

Digital Transformation in the New Zealand Retail Banking Sector: Challenges and Opportunities for Elderly Customers

<p style="text-align: justify;"><span style="font-family: 'times new roman', times, serif; font-size: 14pt;">This research focuses on the digital transformation of retail banking in New Zealand, focusing on the challenges and opportunities elderly customers face. The banking industry is undergoing unprecedented change as technology evolves and customer needs change. However, elderly customers face physical and security challenges associated with digital transformation and lower acceptance of new technologies. This paper analyses the characteristics and needs of elderly customers, investigates the different needs of elderly and young customers, and recommends relevant solutions and suggestions. This investigation is based on secondary data, and recently published articles from various sources were used to collect information. In the wave of digital transformation, banks not only need to strive to provide convenient, safe, and high-quality services, but also need to innovate continuously to meet the needs of all customers and enhance their trust and satisfaction. This report provides exclusive digital service suggestions and solutions to help banks better meet the needs of elderly customers.</span></p>

Understanding climate modes’ impact on the Indian Ocean decadal upwelling variability

<p align="justify">This study explores the spatial pattern and climate modes’ impact on the Indian Ocean decadal upwelling variability by using observational dataset, Static Linear Regression Model (SLM) and Bayesian Dynamic Linear Model (BDLM). Our analysis shows that the Indian Ocean decadal upwellings averaged in the Eastern and Western Indian Ocean (EIO and WIO) regions are positively correlated. Moreover, the BDLM that represents the temporal modulations of the El Niño and Southern Ocean (ENSO) and Indian Ocean Dipole (IOD) impacts, reproduces the time series of the EIO and WIO upwellings more realistically than a conventional SLM does. BD<span style="font-family: 'Times New Roman';">L</span>M simulations further suggest that in both EIO and WIO, IOD is more important than ENSO impact. The time-varying regression coefficients in BDLM indicate that the observed shift of the IOD impact on the EIO upwelling around 1985 is mainly associated with the changes of <span style="font-family: 'Times New Roman';">alongshore </span>wind stress forcing <span style="font-family: 'Times New Roman';">and </span>the sensitivity of the upper <span style="font-family: 'Times New Roman';">ocean </span>temperature <span style="font-family: 'Times New Roman';">in the </span>E<span style="font-family: 'Times New Roman';">IO</span> through the surface warming tendency and the enhanced ocean stratification. This suggests that climate models need to consider the time-varying impact of different climate modes in order to simulate the Indian Ocean dynamics correctly.<strong></strong></p>

Ocurrence of Colletotrichum siamense Causing Leaf Spots on Soursop (Annona muricata) in Mexico.

Soursop (Annona muricata L: Annonaceae) is a small tropical fruit tree native to South America (Pinto, 2005). The flesh of its fruits is widely used as a main ingredient of pastries, even young fruits are used as a vegetable. In June 2022, leaf spots symptoms were observed on fifty soursop plants in a commercial nursery located in Juan José Ríos (25°45'20"N 108°50'21"W), Ahome, Sinaloa State. The incidence of the disease was 75%, while the severity was 12%. Symptoms were round, small black necrotic spots, that grew up to 6 mm in diameter with brown or gray color at the center. Fungal isolation was done on potato dextrose agar (PDA) and Colletotrichum-like colonies were obtained. Five isolates were recovered and purified by single spore culture and only a single morphotype was observed. One random isolate was selected for pathogenicity tests, morphological and molecular characterization. The isolate was deposited in the Culture Collection of Phytopathogenic Fungi of the Biotic Products Development Center at the National Polytechnic Institute under accession no. IPN 13.0102. Colonies in PDA at 25°C grow at a rate of 9.0-14.0 mm/d. After 14 days, the colony was olive to gray with orange conidial masses, and conidia (n =100) were hyaline, aseptate, cylindrical, and straight with rounded ends, measuring 11.5 to 18.5 and 3.5 to 5.5 μm. Appressoria were melanized and circular or oval in shape, measuring 6.0 to 4.0 μm (n=20). According to the morphological characteristics observed, the isolate was placed tentatively within the Colletotrichum gloeosporioides species complex (Weir et al. 2012). For molecular confirmation, genomic DNA was extracted, and the internal transcribed spacer (ITS) region (White et al. 1990), partial sequences of actin (ACT) (Weir et al. 2012) and span style="font-family:'Times New Roman'">glyceraldehyde-3-phosphate dehydrogenase (GAPDH) genes were amplified and sequenced. Sequences were deposited in GenBank under the accession numbers: ITS, OQ606966; ACT, OQ617292 and GAPDH, OQ617293. A phylogenetic tree including published sequences of the C. gloeosporiodes species complex was constructed according to Talhinhas and Baroncelli (2021) and the isolate IPN 13.0102 was grouped in a clade with the ex-type culture of C. siamense (ICMP18578) and C. pandanicola. However, C. pandanicola was recorded only as an epiphytic fungus occurring on leaves of Pandanus sp. (Pandanaceae) (Tibpromma et al. 2018) and there are no additional reports of this fungus as a plant pathogen on Pandanus or any other plant. Therefore, the isolate IPN 13.0102 corresponds to C. siamense. Pathogenicity was demonstrated by spraying a conidial suspension (1 × 105 conidia/ml) onto four healthy soursop plants, while two control plants were sprayed using sterile distilled water. All plants were kept in a wet chamber for 48 h at 28  2°C and 85% RH. The characteristic symptoms of the disease were observed 14 days after inoculation, while control plants remained healthy. The pathogenicity test was repeated twice obtaining the same results. The morphology of the recovered fungus was consistently identical to that originally isolated from diseased leaves, fulfilling Koch's postulates. Colletotrichum siamense has been previously reported on Anona spp. in Brazil (Costa et al. 2019). To our knowledge, this is the first report of Colletotrichum siamense causing leaf spots on Annona muricata in Mexico. Further studies for monitoring and control strategies of leaf spots on soursop are required.

TEACHER PERFORMANCE IMPROVEMENT PLANNING AND LEARNING OPTIMIZATION

<p style="margin: 0cm 0.65pt 0pt 0cm; text-align: justify;"><span style="letter-spacing: -0.05pt; font-family: 'Cambria','serif'; font-size: 12pt; mso-ascii-theme-font: major-latin; mso-hansi-theme-font: major-latin;">Improving teacher performance is the upstream of the success of the learning process, and outstanding students are downstream of the process. This study aims to describe planning for improving teacher performance and optimizing learning. This type of research belongs to the category of qualitative approach with literature study method. Study analysis materials and data sources were obtained from internet-based searches with credible pages, such as Google Scholar, DOAJ, Moraref, and SINTA. The data materials in question include books, scientific articles, proceedings, and student final assignments. Furthermore, the validity or validity of the data is checked using data materials (scientific). The results of this study indicate that planning for improving teacher performance and optimizing learning through the stages of greedy organization, work intensification, performativity, and understanding organizational strengths.</span></p>

IMPLEMENTATION OF THE CRITICAL PATH METHOD (CPM) IN EDUCATIONAL PLANNING

<p style="margin: 0cm 0.65pt 0pt 0cm; text-align: justify;"><span style="letter-spacing: -0.05pt; font-family: 'Cambria','serif'; font-size: 12pt; mso-ascii-theme-font: major-latin; mso-hansi-theme-font: major-latin;">This study aims to describe the application of the Critical Path Method (CPM) technique in educational planning at SD Negeri 101777 Saentis. This study uses a qualitative approach with a descriptive method, to explain the approach and method applied in the form of CPM techniques in educational planning. Obtaining data through observation techniques, interviews and document studies. The research data analysis technique uses data reduction (sorting), data presentation and conclusion drawing. Then, the data will be declared valid after being tested with data triangulation techniques, in the form of checking the data sources and data acquisition methods. The results of this study conclude that the empowerment of human resources (HR) and budget allocation for program financing at SD Negeri 101777 Saentis implement CPM effectively as an effort to prioritize and schedule madrasa programs in a measurable and precise manner. Supporting this, the madrasah also collaborates with various elements of society in assisting education planning at SD Negeri 101777 Saentis, starting from collaboration with non-governmental organizations (NGOs) and government institutions.</span></p>

EFFECTIVENESS OF GROUP GUIDANCE SERVICES IN MINIMIZING SMARTPHONE ADDICTION

<p style="margin: 0cm 0.65pt 0pt 0cm; text-align: justify;"><span style="letter-spacing: -0.05pt; font-family: 'Cambria','serif'; font-size: 12pt; mso-ascii-theme-font: major-latin; mso-hansi-theme-font: major-latin;">Smartphone addiction is a problem among students in the technology era. In this context, guidance from adults (teachers or parents) is needed for children (students). This study aims to determine the effectiveness of group guidance services in minimizing smartphone addiction. The background of this research is at SDN 101910 Sidodadi, specifically the research subjects, namely 30 students of class VI for the academic year 2022/2023 to test how big the level of smartphone addiction is among students, between before and after being given group guidance services. The type of this research is counseling guidance action research (PTBK), carried out in 2 cycles. Data analysis was carried out quantitatively using questionnaires and observations. The results of this study indicate the level of smartphone addiction of VI SDN 101910 Sidodadi students when a pre-test was held on 8 students (26.7%), 2 students in the high category, and 6 students in the very high category. Furthermore, in the first cycle, group guidance services were provided through group discussions, lectures, questions and answers, and filling out questionnaires. There were 2 students (6.7%) who were still addicted to smartphones in the high category and 4 students in the medium category, 2 students in the low category. In cycle II, 1 student (3.3%) was still addicted to smartphones in the high category, 3 students in the low category, and 4 students in the very low category. Thus, it was concluded that the level of smartphone addiction in students decreased after being given counseling services.</span></p>

EFFORTS TO IMPROVE STUDENT LEARNING OUTCOMES THROUGH DEMONSTRATION METHODS IN MATHEMATICS LESSON MATERIALS BUILDING SPACE

<p style="margin: 0cm 0.65pt 0pt 0cm; text-align: justify;"><span style="letter-spacing: -0.05pt; font-family: 'Cambria','serif'; font-size: 12pt; mso-ascii-theme-font: major-latin; mso-hansi-theme-font: major-latin;">This study aims to examine efforts to improve student learning outcomes through demonstration methods in mathematics subjects with building materials in the form of blocks and cubes for fourth grade students of MIN 26 Pidie. This type of research uses classroom action research (CAR), with subjects covering 37 fourth grade students at MIN 26 Pidie. The results of this study conclude that the application of the demonstration method can improve the learning outcomes of fourth grade students at MIN 26 Pidie in mathematics lessons on building materials (cubes and blocks). This is evidenced by the results of the student's pre-test which was originally low, namely 38.64 (none even completed according to the Minimum Completeness Criteria/KKM). The results of the final test in the first cycle that did not use the demonstration method (still conventional method) showed an increase, where 7 students had achieved the KKM score (18.9%) while the other 30 students had not reached the KKM (81.1%). Furthermore, the results of the final test in the second cycle that had used the demonstration method showed a significant increase, where there were 32 students (86.48%) who met the KKM and 5 students (13.52%) who had not reached the KKM.</span></p>

STUDENT READING SKILL TRAINING THROUGH THE DEVELOPMENT OF MULTIMEDIA AS A LEARNING DEVICE

<p style="margin: 0cm 0.65pt 0pt 0cm; text-align: justify;"><span style="letter-spacing: -0.05pt; font-family: 'Cambria','serif'; font-size: 12pt; mso-ascii-theme-font: major-latin; mso-hansi-theme-font: major-latin;">This study aims to develop multimedia as a learning tool in training the reading skills of islamic elementary school (MI) students. This research uses a research and development (R&D) approach, through a Gall & Borg development study. This research is set in MIN 42 Pidie. The learning model is integrated with various learning tools (multimedia) including student and teacher books, as well as lesson plans (RPP). Based on the data obtained, it is known that multimedia integrated with the inquiry instructional model is effective in improving student learning outcomes rather than without using multimedia. It is proven through t-test statistical testing where tcount (9.98) is higher than ttable (2.00), means that multimedia integrated with the inquiry instructional model has a practical level with a score of 3.39 in the practical category without improvement.</span></p>

THE INFLUENCE OF STEAM-BASED PROJECT-BASED LEARNING MODELS ON STUDENTS' LEARNING OUTCOMES IN CLASS IV ENERGY TRANSFORMATION MATERIAL AT MIN 6 BIREUEN

<span style="letter-spacing: -0.05pt; font-family: 'Cambria','serif'; font-size: 12pt; mso-ascii-theme-font: major-latin; mso-fareast-font-family: 'Times New Roman'; mso-hansi-theme-font: major-latin; mso-bidi-font-family: 'Times New Roman'; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;">The importance of choosing a learning model. A good learning model can be used to make the teaching and learning process more effective, meaningful and enjoyable. So that students will get learning outcomes that can meet the minimum completeness criteria (KKM). But the fact is that teaching and learning in class is still not optimal in using learning models. Based on these problems need an update. One of the meaningful, effective, and fun learning alternatives that can be applied in developing student competencies is to use the STEAM-based project based learning model. The formulation of the problem in this study is "Does the STEAM-based project-based learning model affect student learning outcomes in class IV energy transformation material at MIN 6 Bireuen". The purpose of this study was to determine the effect of the STEAM-based project based learning model on student learning outcomes in class IV energy transformation material at MIN 6 Bireuen. This study uses a quantitative approach. This type of research is quasi experimental design. The population in this study were all MIN 6 Bireuen students while the samples were all 20 grade IV students. Data collection techniques used tests, while data analysis techniques used SPSS Statistics 25 by using normality tests and to test hypotheses using paired sample t-tests. The results showed that the significance value (2-tailed) on the test was 0.000 <0.05, where the average value of the learning test results was 85.5. The average value obtained by these students can fulfill the KKM. So it can be said that there is an influence of the STEAM-based project-based learning model on student learning outcomes in energy transformation material</span>

THE CONCEPT OF CHILDREN'S EDUCATION IN THE PERSPECTIVE OF THE QURAN

<p style="margin: 0cm 0.65pt 0pt 0cm; text-align: justify;"><span style="letter-spacing: -0.05pt; font-family: 'Cambria','serif'; font-size: 12pt; mso-ascii-theme-font: major-latin; mso-hansi-theme-font: major-latin;">This study aims to analyze the concept of children's education in the perspective of the Koran. In this context, the essence of the meaning of the term tarbiyah becomes the basic foundation of research. This research uses a qualitative approach with a literature study method. Data collection and analysis was carried out using scientific reference materials, including scientific articles, books, proceedings and final assignments (thesis, theses, dissertations) which were tracked via the internet on the google scholar indexer, DOAJ, science direct, and scimago JR. The results of this study found that the concept of child education in the Qur'an contains an element of "love" like parental education for children in the concept of tarbiyah. The elements of the concept of education for children in the perspective of the Qur'an describe learning obligations, educational goals, the role of educators, educational objects, educational methods, and educational materials for children. Thus, the education given to children is comprehensively based on the worldview of monotheism in realizing human beings (perfect).</span></p>

IMPLEMENTATION OF ISLAMIC RELIGIOUS EDUCATION IN PRAISE MORAL DEVELOPMENT AT SD SWASTA TAHFIDZ SHOHIBUL QUR'AN

<span style="letter-spacing: -0.05pt; font-family: 'Cambria','serif'; font-size: 12pt; mso-ascii-theme-font: major-latin; mso-fareast-font-family: 'Times New Roman'; mso-hansi-theme-font: major-latin; mso-bidi-font-family: 'Times New Roman'; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;">This study aims to describe the implementation of Islamic religious education in building the character of al-Karimah students at SD Swasta Tahfidz Shohibul Qur’an. This study uses a qualitative approach with a descriptive study method, as an effort to describe social reality in a complex and concrete manner. Collecting data using observation techniques, interviews, and documentation studies, as well as checking it with relevant scientific articles. Data analysis was carried out interactively, through the pre-observation stage (preliminary study), implementation stage, data analysis stage, conclusion drawing stage, to reporting research results. The results of this study conclude that (1) PAI learning planning as an effort to develop the quality of student character formation is carried out at the beginning of a new school year, in the form of meeting activities (deliberations), as well as concrete results in the form of preparation of teaching materials and lesson plans; (2) PAI learning is carried out in the classroom (based on the teaching materials and lesson plans that have been prepared) and outside the classroom (covering daily programs, monthly programs and school annual programs); (3) the way teachers evaluate learning refers to the results of student report cards, changes in student attitudes and behavior, and coordination with parents regarding student learning development; and (4) factors that influence PAI learning include school readiness, sympathetic attitude (teachers care), and parental coordination with the school</span>.

THE EFFECTIVENESS OF LEARNING MANAGEMENT IN MIN 6 TAPANULI TENGAH

<p style="margin: 0cm 0.65pt 0pt 0cm; text-align: justify;"><span style="letter-spacing: -0.05pt; font-family: 'Cambria','serif'; font-size: 12pt; mso-ascii-theme-font: major-latin; mso-hansi-theme-font: major-latin;">This study aims to describe the level of effectiveness of public relations management implemented at MIN 6 Tapanuli Tengah, as well as to analyze the process of implementing community relations management can be achieved. The data collection technique used the interview method. This study uses a qualitative approach with a descriptive study method. The research data were obtained from observation guide sheets, interview guidelines, documentation. The results obtained from this research are first, there is good cooperation from all educators and teaching staff as well as management, especially public relations so that there is good communication to parents and the community; and second, there are tangible results when public relations is carried out properly in accordance with what has been programmed, it will get support from the head of the madrasa.</span></p>

DEEP MIND MAPPING MODEL IMPLEMENTATION DEVELOP CHILD CREATIVITY

<p style="margin: 0cm 0.65pt 0pt 0cm; text-align: justify;"><span style="letter-spacing: -0.05pt; font-family: 'Cambria','serif'; font-size: 12pt; mso-ascii-theme-font: major-latin; mso-hansi-theme-font: major-latin;">Children's creativity is a potential that must be developed through the educational process. This study aims to describe the implementation of the mind mapping model in developing children's creativity in akidah akhlak lessons. This study uses a qualitative approach with a descriptive study method. The background of this research is in SDN 068003. Observation techniques, interviews, and document studies are three research data acquisition techniques. Then, the data were analyzed using an interactive analysis model, through the steps of data collection, data sorting, data presentation, and drawing conclusions. The results of this study indicate that the application of the mind mapping model makes it easier for educators during the thematic learning process, because it stimulates students to develop their creativity based on the spirit of group learning. Likewise, there are obstacles in implementing the learning model, namely the low focus of students in group activities, difficulties for teachers to control student learning behavior, and some students like to disturb their friends.</span></p>

COVID-19 a global crisis: Features, complications and suggested treatments

<p><span style="font-size: 10.0pt; font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-fareast-font-family: PMingLiU; mso-hansi-theme-font: minor-bidi; mso-bidi-font-family: PMingLiU; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: EN-US;">Coronavirus disease 2019 (COVID-19); caused by the novel coronavirus (SARS-CoV-2) is the talk of everyone all over the world in 2020 since it has been considered as a public health emergency of international concern by WHO in 30<sup>th</sup> January, 2020. COVID-19 is a highly transmittable disease with different symptoms which can vary from mild to severe and life threatening. Scientists all over the world are working on finding a treatment or vaccine for this disease. All of these studies are currently not finished yet during writing this review. However, in this review a summary about the current status of these studies is given. This summary includes medicinal plants and natural products, antivirals like </span><span style="font-size: 10.0pt; font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-fareast-font-family: 'Times New Roman'; mso-hansi-theme-font: minor-bidi; mso-bidi-font-family: PMingLiU; color: #2e2e2e; mso-font-kerning: .5pt; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: EN-US;">remdesivir, favipiravir,</span><strong><span style="font-size: 10.0pt; font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-fareast-font-family: PMingLiU; mso-hansi-theme-font: minor-bidi; mso-bidi-font-family: PMingLiU; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: EN-US;"> </span></strong><span style="font-size: 10.0pt; font-family: 'Arial',sans-serif; mso-ascii-theme-font: minor-bidi; mso-fareast-font-family: 'Times New Roman'; mso-hansi-theme-font: minor-bidi; mso-bidi-font-family: PMingLiU; color: #2e2e2e; mso-font-kerning: .5pt; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: EN-US;">oseltamivir and nelfinavir as well as other miscellaneous drugs like chloroquine, hydroxychloroquine and ivermectin which showed promising results in treating COVID-19. In conclusion, the review recommends conducting further investigations worldwide and reporting them in peer-reviewed publications to aid in improving the drugs’ dosing regimens and clinical studies. </span></p>