This paper investigates the β-dissipativity-based reliable non-fragile sampled-data control problem for a class of interval type-2 (IT2) fuzzy systems. In particular, it is allowed to have randomly occurring time-varying delays in the controller design, which are modeled by Bernoulli distributed white noise sequences. Precisely, the IT2 fuzzy model and the non-fragile sampled-data controller are formulated by considering the mismatched membership functions. By constructing an appropriate Lyapunov–Krasovskii functional, a set of delay-dependent conditions is derived to guarantee that the closed-loop IT2 fuzzy system is strictly <Q,S,R>-β-dissipative. Moreover, the gain matrices of feedback reliable non-fragile sampled-data controller are derived in terms of linear matrix inequalities (LMIs), which can be solved by using existing LMI solvers. Two numerical examples are eventually given to illustrate the applicability and effectiveness of the proposed controller design technique.