Changes in organizational architecture (e.g., a change toward team-based management, downsizing) and technology innovation are becoming more complicated difficulties that workers must deal with. Opportunities and changing environmental demands that are required by the workers to adopt otherwise work processes have become less formalized. Finding and locating the “right person for the right job” has become extremely necessary for organizations. Nevertheless, who is the “right” choice? How should the capabilities of the employees be unbridled by the organization? Imprecise human solutions and uncertainty can lead which is a predicament. This study examined the determinants of adaptive performance in the healthcare sector of Pakistan. Also, examined the mediating role of the thriving and moderating role of psychological capital. Data were collected from 420 doctors working in private and government hospitals having experience in middle-level and upper-level management based on the convenience sampling technique. Statistical software SPSS and SMART PLS were used for data analysis. Results validates the hypothesis and question for the research to achieve the aims of the study. Based on the findings for direct and indirect hypothesized relationships found strong empirical support. This research contributes to a more in-depth understanding of the constructs, Abusive supervision, Workplace Incivility, Pro-Social Motivation, Thriving, Psychological Capital, and Adaptive Performance. Limitations suggested some guidelines for future studies. Research implications (theoretical and practical) were provided.