The elimination of necrotic pulp tissue from the root canal is important for the ultimate success of a root-canal operation. To attain this end, both mechanical and chemical means are employed. Among chemical agents used for this purpose may be mentioned sulfuric acid (Callahan'), sodium-potassium alloy (Schreier2), sodium dioxide (Kirk3), sodium methylate (Levene4), papain (Wilkinson 5) and chlorinated soda solution (Walker6). Solutions of hydrochloric acid, sodium hydroxide and potassium hydroxide have also been used and advocated for disintegration or solution of pulp tissue. Of historical rather than practical interest is the use of maggots for cleansing the canal of necrotic tissue, as suggested by Dreher. 7 The purpose of this study was to determine which of the agents already mentioned, or others believed to have a solvent action on tissue, is more effective. Sponer, 8 Blum 9 and Holst and Pedersen ~~ undertook somewhat similar studies, limiting themselves to fewer chemical agents or including proprietary agents not known in this country. M E T H O D
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