This study aims to determine the relationship between menstrual symptom experience, the presence of menstrual symptoms in the family, and perceived social support in women of reproductive age. This descriptive and cross-sectional study was conducted with women aged 18–49 living in XXX on online platforms between April 1 and June 30, 2022. Participants were invited to the study through social media platforms. The women 942 constituted the sample of the research. The mean age of the women who participated in the study was 28.45±6.75 years. Of the participating women, 80.1% reported that they had regular menstruation and 71.1% had a family history of menstrual symptoms. The mean total scores of the Menstruation Symptom Questionnaire (MSQ) and Multidimensional Perceived Social Support Scale (MSPSS) were 63.02±16.07 and 66.97±14.95, respectively. The results of the study showed a strong relationship between experiencing menstrual symptoms and a history of menstrual symptoms in the family. There was a low-level significant relationship between experiencing menstrual symptoms and social support. Accordingly, it is recommended to conduct more studies on the relationship between social support and menstrual symptoms using an increased sample size and prospective methods.