Small Variations Research Articles

Techno-economic assessment and wind energy potential of Nagad in Djibouti

The use of small scaled horizontal and vertical axis wind turbines in urban installation is increasing over the world. However, in Djibouti, the latter is still in the development phase. The paper presents a techno-economical analysis and wind energy potential for the period of five years (2015-2019) in Nagad based on actual measured wind speed data collected every 10 min at 10 m height. The energy pattern factor method has been used to estimate the Weibull parameters. With this method, the mathematical complexity is reduced with a minimization of the error at any heights and locations when calculating the wind power density. At 50 m height, the shape parameter showed a small variation for different periods. The scale parameter values of 7.78 m/s and 4.8 m/s were obtained in the hot and cold seasons, respectively. The results showed that the Nagad site is suitable for wind power development. According to the economic viability, RX30, Vestas V20, Enercon, Nordex N27, and Vestas V44 wind turbines are recommended for the Nagad site due to their low energy price ranging from 0.05$/kWh to 0.31$/kWh. This is 2-6 times cheaper than the average local tariff of electricity in Djibouti.

Creep behaviour of adhesively bonded joints: A comprehensive review

This review paper provides an exploration of various facets of creep behaviour in adhesives and adhesive joints, encompassing experimental procedures, prediction models, influential parameters and strategies to enhance resistance. The discussion extends to the interplay between fatigue and creep, emphasising recent advances over the last two decades. While avoiding redundancy with prior work on temperature and moisture degradation, the paper articulates connections between topics for a better understanding. A critical examination of load levels reveals that small variations significantly impact the creep life of adhesive joints, particularly prominent with epoxy adhesives. The adhesive type, joint geometry and substrate material are scrutinised, revealing distinct impacts on creep behaviour. The study underscores the critical role of adhesive thickness and overlap length, emphasising their relevance in determining the time to failure in bonded joints under creep conditions. Notably, the substrate material’s role is highlighted. As the review delves into unexplored dimensions, it calls for further research to bridge existing gaps and refine our understanding of tertiary creep and time until failure.

Evaluation of venom diversity and antivenom quality from the venom of long-term captive vs recently wild captured Pseudocerastes persicus snake: An In vitro and In vivo study

Snakebite envenomation is a life-threatening condition and antivenoms are used as the most effective treatment. Venom obtained from snakes in long-term captivity showed some variations in comparison to the venom of the wild snakes. The objective of this study is to compare the venom of the Pseudocerastes persicus under long-term captivity and wild conditions as well as the antivenom obtained from these venoms. We have analyzed venom samples and produced trivalent antivenoms using the venom of long-term captive (LTC) or recently wild-captured (RWC) Pseudocerastes persicus, and RWC Macrovipera lebetina, and Echis carinatus. The HPLC analysis revealed that the RWC snakes' venom had three peaks that were not present in the LTC snake's venom. Further analysis using MALDI-TOF and MS/MS showed that the fraction with a retention time (RT) of 14 min contained a toxin from the Kunitz-type serine protease inhibitor (KUT) class, while the fraction with RT 21 a peptide identified within the snake venom metalloproteinase (SVMP) class. The third peak was identified as a sphingolipid.Interestingly, the in vivo preclinical tests showed no significant differences in the effectiveness of the antivenoms. which could be due to the cross-immunogenicity or cross-reactivity between different toxins in the venom. According to our results, small variations in the venom composition of a species do not lead to a decrease in the efficacy of the polyvalent antivenom.

Oxygen Isotope Fractionation Due to Non-Thermal Escape of Hot O from the Atmosphere of Mars

Secondary minerals in SNC meteorites from Mars exhibit O isotope ratios believed to be consistent with the non-thermal escape of O from the atmosphere. The primary source of the non-thermal O is the dissociative- recombination of O2+ in the ionosphere. I present here the results of a model that accounts for the probability of escape of non-thermal O isotopes due to collisions with overlying CO2, combined with a model for Rayleigh fractionation of the atmosphere remaining as a result of O escape. Previous analyses of MAVEN number density data have shown a strong variability with latitude and season of the heights of the homopause and exobase, with a mean homopause at 110 km and a mean difference of about 60 km. Rayleigh model results demonstrate a dependence on homopause height and on temperature profile and require a more accurate calculation of fractionation factors for the Rayleigh equation. Isothermal temperature profiles yield much smaller variation in 17O with homopause height. These results demonstrate the need for a careful assessment of O isotope enrichment due to non-thermal escape both for the modern atmosphere and for the evolution of the atmosphere over the age of the planet.

High‐performance bismuth titanate‐ferrite (Bi5Ti3FeO15) for high‐temperature piezoelectric applications

AbstractAdvancing the development of high‐temperature piezoelectric sensors requires high‐performance piezoelectric materials with high Curie temperatures, wherein the charge signals can be efficiently collected at elevated temperatures. The bismuth layer‐structured ferroelectric (BLSF) bismuth titanate‐ferrite (Bi5Ti3FeO15, BTF) has recently attracted considerable attention because of its high Curie temperature (TC) of ∼761°C. However, the piezoelectric properties of BTF‐based compounds have not been extensively investigated because of their extremely poor piezoelectric performances and low electrical resistivities at elevated temperatures. Herein, tungsten‐substituted BTF (BTF‐100xW) ceramics were synthesized using a solid‐state reaction method. X‐ray diffraction refinement results confirmed the lattice distortion of the BO6 octahedron, while piezoelectric force microscopy images verified an increase in the domain wall density with tungsten modification, both of which contribute to significant enhancement of the piezoelectric properties of BTF‐100xW as intrinsic and extrinsic contributions, respectively. Remarkably, BTF‐3W exhibits a high TC of 793°C and a large piezoelectric constant (d33) of 24.3 pC/N, which is over three times that of BTF (7.1 pC/N). Importantly, the substitution of tungsten decreases the concentration of oxygen vacancies, increases the direct current electrical resistivity, and improves the electrical homogeneity at high temperatures, resulting in extremely stable piezoelectric and electromechanical properties at high temperatures, with a high in‐situ relative d33 of >90% at 400°C and a small variation in the electromechanical coupling factor (kp) of <8% at temperatures up to 450°C. These results suggest that the tungsten‐substituted BTF is a potential candidate for high‐temperature piezoelectric ceramics, and is a promising material for applications in high‐temperature piezoelectric sensors.

Pedostratigraphic age model for Devonian red beds of NW China

Detrital zircon geochronology has been used to determine provenance, but also gives maximum depositional ages that can constrain other forms of geochronology, such as magnetostratigraphy and pedostratigraphy. Pedostratigraphy and magnetostratigraphy correlate a series of global events by spacing or intensity in a fashion comparable with a commercial barcode. The Late Devonian Shaliushui Formation of NW China is poorly fossiliferous, but shows spikes in magnetic susceptibility, Al/Si ratios, Rb/Sr ratios and the depth to carbonate nodules (Bk horizon) corresponding with the timing of named Late Devonian black shale horizons. By contrast, the Ti/Al ratios show only small variations, indicating little long-term change in the source terrain or in the hydraulic sorting of heavy minerals. Most of the detrital zircon ages are older than an age model from the pedostratigraphic correlation of deep calcic horizons corresponding to global atmospheric CO 2 spikes at times of black shale expansion, but one detrital zircon age converges with the pedostratigraphic depositional ages near the top of the section. Pedostratigraphy is widely used in Quaternary sequences, but can also be a basis for age models of rocks in deep time if supported by detrital zircon ages. Supplementary material: Paleosol and geochemical data, and youngest zircon ages for a section of Devonian rocks near Ciyao, Gansu, China are available at https://doi.org/10.6084/m9.figshare.c.7008192

Coiling of Secondary Tubes Formed from the Colloidal Exhaust of Primary Chemical Gardens.

Chemical gardens are self-organized precipitate structures such as thin-walled tubes and membrane-bound cells reminiscent of biological shapes. These usually inorganic precipitates compartmentalize the reaction system and allow the study of materials synthesis in very steep concentration gradients. We create such tubes by steadily injecting a mixture of MnCl2 and CuSO4 solutions into a large reservoir of sodium silicate solution. The growing tube is open at its tip and ejects a stream of colloidal particles that aggregate to form a secondary tube above the original one. This secondary tube can coil into a tightly wound nest-like structure, freely suspended underneath the solution-air interface. Using three-dimensional image reconstruction, we analyze the onset of coiling and show that the structure is helical with a helix radius that increases in the vertical direction. The height at which the coiling begins is lowered with each successive repeat of the growth experiment, suggesting that coiling is induced by small variations in the density of the silicate solution.

Effects of Nano-Electrospray Ionization Emitter Position on Unintentional In-Source Activation of Peptide and Protein Ions.

Native ion mobility-mass spectrometry (IM-MS) typically introduces protein ions into the gas phase through nano-electrospray ionization (nESI). Many nESI setups have mobile stages for tuning the ion signal and extent of co-solute and salt adduction. However, tuning the position of the emitter capillary in nESI can have unintended downstream consequences for collision-induced unfolding or collision-induced dissociation (CIU/D) experiments. Here, we show that relatively small variations in the nESI emitter position can shift the midpoint (commonly called the "CID50" or "CIU50") potential of CID breakdown curves and CIU transitions by as much as 8 V on commercial instruments. A spatial "map" of the shift in CID50 for the loss of heme from holomyoglobin onto the emitter position on a Waters Synapt G2-Si mass spectrometer shows that emitter positions closer to the instrument inlet can result in significantly greater in-source activation, whereas different effects are found on an Agilent 6545XT instrument for the ions studied. A similar effect is observed for CID of the singly protonated leucine enkephalin peptide and Shiga toxin 1 subunit B homopentamer on the Waters Synapt G2-Si instrument. In-source activation effects on a Waters Synapt G2-Si are also investigated by examining the RMSD between CIU fingerprints acquired at different emitter positions and the shifts in CIU50 for structural transitions of bovine serum albumin and NIST monoclonal antibody.

Differential pressure sensors based on transfer-free piezoresistive layered PdSe2 thin films

Piezoresistive layered two-dimensional (2D) crystals offer intriguing promise as pressure sensors for microelectromechanical systems (MEMS) due to their remarkable strain-induced conductivity modulation. However, integration of the conventional chemical vapor deposition grown 2D thin films onto a micromachined silicon platform requires a complex transfer process, which degrades their strain-sensing performance. In this study, we present a differential pressure sensor built on a transfer-free piezoresistive PdSe2 polycrystalline film deposited on a SiN x membrane by plasma-enhanced selenization of a metal film at a temperature as low as 200 °C. Based on the resistance change and finite element strain analysis of the film under membrane deflection, we show that a 7.9 nm thick PdSe2 film has a gauge factor (GF) of −43.3, which is ten times larger than that of polycrystalline silicon. The large GF enables the development of a diaphragm pressure sensor with a high sensitivity of 3.9 × 10−4 kPa−1 within the differential pressure range of 0–60 kPa. In addition, the sensor with a Wheatstone bridge circuit achieves a high voltage sensitivity of 1.04 mV·kPa−1, a rapid response time of less than 97 ms, and small output voltage variation of 8.1 mV in the temperature range of 25 °C to 55 °C. This transfer-free and low-temperature grown PdSe2 piezoresistive thin film is promising for MEMS transducer devices.

A comprehensive review of deep learning-based variant calling methods.

Genome sequencing data have become increasingly important in the field of personalized medicine and diagnosis. However, accurately detecting genomic variations remains a challenging task. Traditional variation detection methods rely on manual inspection or predefined rules, which can be time-consuming and prone to errors. Consequently, deep learning-based approaches for variation detection have gained attention due to their ability to automatically learn genomic features that distinguish between variants. In our review, we discuss the recent advancements in deep learning-based algorithms for detecting small variations and structural variations in genomic data, as well as their advantages and limitations.

A Computational exploration of the electronic, mechanical, and magnetic properties of Co2A1−xBxAl full heusler alloys (A, B = Cr, Mn, and Fe)

An investigation of the structural, mechanical, electronic, magnetic, and thermomagnetic properties of Co2A1−xBxAl full Heusler alloys (where A, B = Cr, Mn, and Fe, and x ranges from 0 to 1.0) has been carried out using density functional theory (DFT) and Monte Carlo simulations. The investigation reveals small variations in lattice parameters and elastic modulus across the different compositions. The band gaps, calculated using modified Becke-Johnson (mBJ) potential, are found to be approximately 1.4 eV for Co2CrAl and Co2MnAl, while a lower band gap of 0.8 eV is observed for Co2FeAl, which also exhibits the highest total magnetic moment of 5 μB. The doped structures display band gaps and magnetic moments that are intermediate to the pure compounds. The Fe-Co exchange interaction is identified as the most robust, significantly contributing to the high Curie temperatures in Fe-containing compounds, reaching up to 1120 K in the Co2FeAl alloy. Furthermore, the study underscores the strategic use of atomic substitution as an effective approach to manipulating key properties of these Heusler alloys. The ability to modulate band gaps, magnetic moments, and Curie temperatures through atomic substitution offers a promising pathway for optimizing these materials for specific technological applications, aligning with the needs of advanced functional devices.

Generalized multivariate EWMA control chart supplemented with bivariate ranked set techniques

ABSTRACT Existing univariate exponential weighted moving average (EWMA) control charts with ranked set schemes are used for monitoring related characteristics independently. Also, existing multivariate EWMA control charts are generally applicable for simple random sampling (SRS) based processes. In this work, a generalized multivariate EWMA control chart is proposed with bivariate ranked set techniques (BVRST) for simultaneously monitoring. Furthermore, an extensive comparative analysis between proposed generalized multivariate EWMA and classical control chart is conducted. In this regard, we have used various performance measures, which cover average run length, median of run length, relative average run length, performance comparison index, and extra quadratic loss. The performance measures are obtained using the Monte Carlo simulation (MCS) approach. Results revealed that the proposed generalized multivariate EWMA control chart has an outstanding detection ability relative to the existing multivariate control charts. Additionally, existing multivariate control charts are found special cases of the proposed control chart. A real-life example from the agriculture field is included in which chemical properties (residual sodium and calcium-magnesium contents) of irrigation water are monitored through the control charts. The results revealed that the proposed control chart is proficient in diagnosing small variations in the chemical characteristics relative to the existing control charts.

Aromaticity of six-membered nitro energetic compounds through molecular electrostatic potential, magnetic, electronic delocalization and reactivity-based indices

The electron density depletion associated with π-hole at the ring center typical of energetic compounds was clearly revealed by the molecular electrostatic potential (ESP). In addition, the spatial arrangement of NO2 groups appears to affect the ESP value in the ring center, and therefore sensitivity to detonation. Indeed, for monocyclic nitrobenzene compounds with the same number of NO2 groups, the ESP value in the ring center decreases as the NO2 groups are more closely spaced. As expected, the central rings become less aromatic as NO2 groups are added. The MCI, PDI, PLR, NICSzz(1), FLU indices are all strongly correlated with the ESP values observed in the ring center of the set of nitrobenzenes. Aromaticity indices based on electron delocalization criteria appear to be very sensitive to small variations in aromaticity. Among magnetic-based indices, only NICSzz(1) is capable to predict small changes in aromaticity. The PLR index derived from conceptual DFT is quite relevant for predicting small variations in aromaticity. According to our results, the most suitable aromaticity index is not based on a single criterion, and that selecting it is more subtle. Therefore, it is important to combine information from several criteria to obtain a more complete description of the aromaticity of the studied compounds.

Surface texture analysis in polycrystalline alloys via an artificial neural network

Surface finish has a significant impact on the properties (e.g., fatigue strength and corrosion resistance) of manufactured products; consequently, industries seek to quantitatively evaluate the surface finish of their products. The surface finish of test specimens, made of the aluminum alloy AL7075−T6, has been measured with a confocal microscope, where the ensemble of collected experimental data has been analyzed by the following four methods of surface texture quantification: (i) arithmetical mean height Sa; (ii) root mean square height Sq; (iii) maximum height Sz; and (iv) ten-points height S10z. This paper addresses automated prediction of surface quality by an artificial neural network (ANN) that has been used to classify the analyzed values of surface textures based on the concept of pattern recognition. The best surface textures are determined by relying on the performance of the ANN model, which depends on the accuracy, precision, recall, and F1-score of the test data. The results show that, for small variations in surface finishing, the test method S10z most accurately predicts quality of surface textures, which is followed by the test method Sa.

Conventional band demultiplexer with high quality factor and transmission power based on four optimized shaped photonic crystal resonators

Abstract In this work, we propose a new filter design based on a ring resonator. This structure has 99% transmission ratio and high sensitivity to detect small refractive index variations of the order of 0.002. More specifically, the small size of this resonator gives the advantage to model a demultiplexer of size 463 µm2 based on four ports which operates in the conventional transmission band. Also, we show that our demultiplexer structure can reach more than 90% transmission ratio with an optical quality factor of about 3800, the spectral width is 0.72 nm and a crosstalk between −13.28 and −32.13. In our study, we emphasized the plane wave method to study the photonic band gap and FDTD to determine the transmission spectrum.

The impact of reduced routine community mental healthcare on people from minority ethnic groups during the COVID-19 pandemic: qualitative study of stakeholder perspectives.

Enduring ethnic inequalities exist in mental healthcare. The COVID-19 pandemic has widened these. To explore stakeholder perspectives on how the COVID-19 pandemic has increased ethnic inequalities in mental healthcare. A qualitative interview study of four areas in England with 34 patients, 15 carers and 39 mental health professionals from National Health Service (NHS) and community organisations (July 2021 to July 2022). Framework analysis was used to develop a logic model of inter-relationships between pre-pandemic barriers and COVID-19 impacts. Impacts were largely similar across sites, with some small variations (e.g. positive service impacts of higher ethnic diversity in area 2). Pre-pandemic barriers at individual level included mistrust and thus avoidance of services and at a service level included the dominance of a monocultural model, leading to poor communication, disengagement and alienation. During the pandemic remote service delivery, closure of community organisations and media scapegoating exacerbated existing barriers by worsening alienation and communication barriers, fuelling prejudice and division, and increasing mistrust in services. Some minority ethnic patients reported positive developments, experiencing empowerment through self-determination and creative activities. During the COVID-19 pandemic some patients showed resilience and developed adaptations that could be nurtured by services. However, there has been a reduction in the availability of group-specific NHS and third-sector services in the community, exacerbating pre-existing barriers. As these developments are likely to have long-term consequences for minority ethnic groups' engagement with mental healthcare, they need to be addressed as a priority by the NHS and its partners.

Quasi-periodic orbits of small solar sails with time-varying attitude around Earth–Moon libration points

This paper proposes new quasi-periodic orbits around Earth–Moon collinear libration points using solar sails. By including the time-varying sail orientation in the linearized equations of motion for the circular restricted three-body problem (CR3BP), four types of quasi-periodic orbits (two types around L1 and two types around L2) were formulated. Among them, one type of orbit around L2 realizes a considerably small geometry variation while ensuring visibility from the Earth if (and only if) the sail acceleration due to solar radiation pressure is approximately of a certain magnitude, which is much smaller than that assumed in several previous studies. This means that only small solar sails can remain in the vicinity of L2 for a long time without propellant consumption. The orbits designed in the linearized CR3BP can be translated into nonlinear CR3BP and high-fidelity ephemeris models without losing geometrical characteristics. In this study, new quasi-periodic orbits are formulated, and their characteristics are discussed. Furthermore, their extendibility to higher-fidelity dynamic models was verified using numerical examples.

How Experiments Help Campaigns Persuade Voters: Evidence from a Large Archive of Campaigns’ Own Experiments

Political campaigns increasingly conduct experiments to learn how to persuade voters. Little research has considered the implications of this trend for elections or democracy. To probe these implications, we analyze a unique archive of 146 advertising experiments conducted by US campaigns in 2018 and 2020 using the platform Swayable. This archive includes 617 advertisements produced by 51 campaigns and tested with over 500,000 respondents. Importantly, we analyze the complete archive, avoiding publication bias. We find small but meaningful variation in the persuasive effects of advertisements. In addition, we find that common theories about what makes advertising persuasive have limited and context-dependent power to predict persuasiveness. These findings indicate that experiments can compound money’s influence in elections: it is difficult to predict ex ante which ads persuade, experiments help campaigns do so, but the gains from these findings principally accrue to campaigns well-financed enough to deploy these ads at scale.

Quantitative monitoring of tensile force in post-tensioning systems using piezoelectric wave method

ABSTRACT The tensile force of a post-tensioning system is essential in prestressed concrete structures. Since the tensile force is related to the contact pressure at the interface between the anchor head and the bearing plate, this study utilizes the piezoelectric wave method to quantitatively monitor the reflected wave energy at the interface. A 3D solid element model was developed to simulate the propagation of stress waves in a simplified anchorage system across different contact areas. Three independent tests were conducted on a simplified 2-strand anchorage system, using the reception coefficient as a monitoring index. The empirical fitting formula between the reception coefficient and the load is derived from the loading data and verified using the unloading data. The experimental results demonstrate good monotonicity and stability within the test range. The study also conducted two temperature-based tests to investigate the effect of small temperature variations on the proposed method. The results indicate that temperature fluctuations of less than 20°C have little effect on the test method. Then, the proposed method is applied to a real 2-strand anchorage system in a concrete beam. The proposed method serves as a reference for quantitatively monitoring the prestressing force of a post-tensioning system.

Mapping nanoscale carrier confinement in polycrystalline graphene by terahertz spectroscopy

Terahertz time-domain spectroscopy (THz-TDS) can be used to map spatial variations in electrical properties such as sheet conductivity, carrier density, and carrier mobility in graphene. Here, we consider wafer-scale graphene grown on germanium by chemical vapor deposition with non-uniformities and small domains due to reconstructions of the substrate during growth. The THz conductivity spectrum matches the predictions of the phenomenological Drude–Smith model for conductors with non-isotropic scattering caused by backscattering from boundaries and line defects. We compare the charge carrier mean free path determined by THz-TDS with the average defect distance assessed by Raman spectroscopy, and the grain boundary dimensions as determined by transmission electron microscopy. The results indicate that even small angle orientation variations below 5° within graphene grains influence the scattering behavior, consistent with significant backscattering contributions from grain boundaries.