When Journal of Systemic Therapies Editor Jim Duvall asked for input about pivotally important—even essential—publications in the emergence of systemic brief therapies, the research and publications of the Palo Alto Group immediately came to mind. There are many noteworthy contributors to systemic thinking and practice, yet the pervasive influence of this small group of researchers stands almost unparalleled. First in Gregory Bateson’s research team (1952–1961), continuing at the Mental Research Institute (MRI) and later in the MRI Brief Therapy Center (1958– present) the contributions of Gregory Bateson, Don D. Jackson, John Weakland, Jay Haley, William Fry, and later Virginia Satir, Richard Fisch, Paul Watzlawick, and colleagues revolutionized systemic understanding of human behavior and methods for promoting change efficiently and effectively. Systemic epistemology and models of therapy as currently known and practiced stand solidly on the foundation built by what has come to be known as the Palo Alto Group. Imagine being a therapist in 1961, well trained in the individually oriented approaches so prevalent at that time, when Jackson and Weakland’s “Conjoint Family Therapy: Some Considerations on Theory, Technique, and Results” appeared in the journal Psychiatry. Freudian concepts and practices pervaded the behavioral sciences. Most therapeutic theory, clinical practice, and literature focused on identifying and either accepting as incurable or attempting to treat pathology located inside the individual. While the Interpersonal Theory of Harry Stack Sullivan, M.D. (1947), and colleagues such as Frieda Fromm-Reichmann, M.D. (1950), had gained wider acceptance, the focus of theory and clinical practice remained almost exclusively on individual pathology and biology, and was past causal in orientation. One wonders what it was like to read the research papers from the Palo Alto Group. The appearance of “Toward a Theory of Schizophrenia” (Bateson, Jackson, Haley, & Weakland, 1956), “The Question of Family Homeostasis” (Jackson,