TOPIC: Cardiovascular Disease TYPE: Fellow Case Reports INTRODUCTION: Sinus of Valsalva dissection is extremely rare and life threatening. It commonly occurs after coronary intervention and can involve right or left sinus of Valsalva. We present a rare case of spontaneous localized dissection of sinus of Valsalva involving non-coronary cusp which was diagnosed with multi-modality imaging. CASE PRESENTATION: 65 year old woman with history of non-ischemic cardiomyopathy was admitted to the hospital for management of new onset atrial fibrillation with rapid ventricular rate. Rhythm control approach was opted after the initial rate control. Transthoracic echocardiogram showed left ventricular ejection fraction of 35% and moderate aortic regurgitation. Transesophageal echocardiogram performed to evaluate for left atrial appendage thrombus prior to cardioversion revealed an aortic dissection limited to sinus of valsalva. She underwent a CTA aorta which was negative for dissection. Cardiac gated MRI was performed to evaluate her aortic root which showed a small intimal flap with limited dissection of sinus of Valsalva at non-coronary cusp of the aortic valve. On review of images and history, the dissection was thought to be chronic and probably related to a diagnostic cardiac catheterization that was performed a month before her admission. After discussion with cardiothoracic surgery decision was made to medically manage the patient with serial imaging given her poor functional status and chronicity of the limited dissection. On one month follow-up patient remained stable and asymptomatic. DISCUSSION: Aortic dissection confined to sinus of Valsalva is a rare but life-threatening. The incidence of this has not been reported in literature. These cases are mostly diagnosed during pre-operative TEE or incidentally. Localized sinus of Valsalva dissections is easily missed on a CTA as the temporal and spatial resolution in these areas are compromised due to large vibrations by aortic valve. TEE is superior in diagnosing these types of dissections. Gated cardiac MRI can be helpful in some cases. CONCLUSIONS: Aortic dissection localized to sinus of Valsalva presents a clinical challenge in terms of diagnosis and management. High index of suspicion and multimodality imaging approach is often required to arrive at the right diagnosis. Given the rarity of this condition the guidelines on the management are limited. REFERENCE #1: Fukui T. Management of acute aortic dissection and thoracic aortic rupture. J Intensive Care. 2018;6:15. Published 2018 Mar 1. REFERENCE #2: Erbel R, Aboyans V, Boileau C, et al. 2014 ESC Guidelines on the diagnosis and treatment of aortic diseases Eur Heart J. 2014;35(41):2873-2926. REFERENCE #3: Hiratzka LF, et al ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with thoracic aortic disease. Catheter Cardiovasc Interv. 2010 Aug 1;76(2):E43-86. doi: 10.1002/ccd.22537. PMID: 20687249. DISCLOSURES: No relevant relationships by Shruti Hegde, source=Web Response No relevant relationships by Kalyan Potu, source=Web Response No relevant relationships by Omar Siddiqui, source=Web Response
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