Abstract Objective Despite getting sufficient sleep being one of the most important things that we can do to keep our body and mind healthy, sleep deprivation has become a major public health concern. This study aimed to determine the prevalence of sleep deprivation and its associated factors among students of the Institute of Health in Jimma University. Methods An institution-based cross-sectional study was conducted from April 10 to April 24 in 2019. Data were collected from 365 randomly selected participants and analyzed using Statistical Package for the Social Sciences (SPSS; version 23). Multivariate logistic regression analysis was used to identify the factors associated with sleep deprivation. The level of significance was declared at a P-value of <0.05. Results A total of 365 participants participated, with a response rate of 97.6%. The study findings showed that 60.8% of students had sleep deprivation and 68.2% had sleep latency. Health problems (adjusted odds ratio [AOR] = 1.91 [95% confidence interval {CI} = 1.01–3.58]), alcohol consumption [AOR = 0.42 (95% CI = 0.2–0.89)], cigarette smoking [AOR = 0.31 (95% CI = 0.09–0.93)], khat chewing [AOR = 0.47 (95% CI = 0.12–0.82)], use of an electronic device before bedtime [AOR = 5.26 (95% CI = 1.78–15.52)], and cumulative grade point average (CGPA) [AOR = 0.48 (95% CI = 0.27–0.83)] were significantly associated with sleep deprivation. Conclusions Sleep deprivation was common in the study area. This is mainly due to health problems, substance utilization, long-time use of an electronic device, and low CGPA. Therefore, a strategy and system should be established to limit substance use, enhance proper use of electronic devices, and create awareness on the impact of nonoptimal sleep.
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