Now a day’s the majority of Indians are affected by the persistent skin illness known as acne vulgaris. Sebaceous glands are involved in the chronic inflammatory skin condition known as acne. Propionibacterium acnes (P. acne), altered follicular keratinization, inflammation, and androgen-induced enhanced sebum hyper-production are four primary pathophysiology. Due to their minimal adverse effects, many now prefer using herbal products over synthetic ones. We create the anti-acne face cream using ingredients like Manjishtha, Aloe Vera, and almond oil. Indian madder, also known as Rubia cordifolia, is found close to streams and rivers. It contains additional qualities including anti-ageing, anti-inflammatory, antibacterial, etc. and is typically used to treat acne. Almond oil is filled with vitamin E, and aloe vera is advantageous and mostly used to cure skin conditions. Certain evaluation test are performed to check whether cream suitable for human skin, its checks whether cream cause the irritancy after applying to skin or not.