In this paper, first we recall the notion of Hom-Jordan superalgebras and study their representations. We define the Yang-Baxter equation in a Hom-Jordan superalgebra. Additionally, we extend the connections between O-operators and skew-symmetric solution Yang-Baxter equation of Hom-Jordan superalgebras (HJYBE). In which, we prove that a super skew-symmetric solution of HJYBE can be interpreted as an O-operator associated to the coadjoint representation. Finally, we study the relationship between Hom-pre-Jordan superalgebras and Hom-Jordan superalgebras via O-operators. Some other related results are considered.