The characteristics of pressure pulsations in centrifugal pumps have attracted considerable attention. In this study, principal component analysis is used to discuss the pressure pulsations in a centrifugal pump with a low specific speed, and the primary causes for these pressure pulsations are analyzed in conjunction with experimental results. The results indicate that principal component analysis effectively separates the primary modes that influence the flow field characteristics. An excessive wrap angle results in the formation of a backflow vortex on the working face of the blade. Obvious stratification of the zero-order modal pressure indicates that the geometric structure of the impeller is rational and that the transient flow field is stable. The second- and third-order modes are conjugates, and their dominant frequency coincides with the dominant rotating frequency of the impeller, indicating that the pulsations of a single channel are the primary component of the pressure pulsations. The primary frequency (148.54 Hz) of the pressure pulsations at monitoring points distributed across the volute is three times the rotational frequency (49.51 Hz) of the impeller. The different positions and sub-frequencies of the monitoring points mean that the principal component analysis can effectively identify the impeller-induced sub-frequency difference.