Objective: To assess and compare the relationship between spousal communication, fertility preference, and other factors with contraceptive use among married couples in Ekiti State, Nigeria. Methods: This cross-sectional study was carried out in Ado- Ekiti Local Government Area of Ekiti State, Nigeria between the 12th of August 2017 and the 15th of February 2018. A pre-tested, semi-structured interviewer-administered questionnaire was used to collect data from 976 respondents by a multi-stage sampling technique. Data were analyzed (univariate, bivariate, and binary logistic regression analysis) using SPSS version 24.0. Factors that showed statistical significance (P<0.05) were included in a binary logistic regression to determine significant predictors of contraceptive use. Results: The proportion of respondents currently using contraceptives was 56.9%. The education status of the respondents revealed that those with primary education were more likely to use contraceptives than those without formal education [adjusted odds ratio (aOR) 8.4, 95% confidence interval (CI) 1.97-36.2, P<0.001]. Respondents with fair spousal communication were more likely to use contraceptive than those with poor communication (aOR 4.9, 95% CI 2.80-8.71, P<0.001). In addition, fertility preference of 4 or less children was found to be significantly associated with contraceptive use (aOR 3.0, 95% CI 1.67-5.50, P<0.001) compared to a preference of more than 4 children. Finally, the urban respondents were more likely to use contraceptives than those in the rural setting (aOR 1.7, 95% CI 1.16-2.41, P=0.047). Conclusions: Educational status, residential site, spousal communication, and fertility preference significantly influence the level of contraceptive use among married couples. Couples should endeavor to discuss more on issues bordering on their fertility preference and contraceptive issue. Government should formulate policies to improve the rural uptake of contraceptives using identified target interventions.
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