Side Of Cavity Research Articles

Unveiling the Rarity: A Fascinating Case of Chondro-Osseous Respiratory Epithelial Adenomatoid Hamartoma (COREAH) in the Sinonasal Tract.

Chondro-osseous respiratory adenomatoid hamartoma (COREAH) are extremely rare benign lesions of the sinonasal tract. It is present in 3 to 83-year-olds. It originates from various sites of the sinonasal tract; the most common site is the posterior lateral wall of the nasal cavity. Imaging calcification is an important finding in COREAH. In this case report, we present an exceptionally rare occurrence involving a 55-year-old female patient who exhibited symptoms of nasal obstruction, bleeding from the left side of the nasal cavity and loss of smell. We aim to share our experience in managing this unique condition. Diagnostic nasal endoscopic examination of the patient revealed a reddish, fleshy polypoidal mass in the left nasal cavity arising from the lateral wall of the left nasal cavity posteriorly and extending anteriorly into the left nasal cavity. The patient underwent an excisional biopsy. Upon microscopic examination, we observed a hamartomatous proliferation of respiratory-type glands exhibiting mucinous metaplasia. Additionally, numerous spicules of mature bone were present, a distinctive feature of COREAH. The patient underwent a 6-month follow-up, during which no recurrent growth was detected within the nasal cavity.

Experimental study on influence of temperature on breakdown in a waveguide cavity

Radio frequency (RF) breakdown is one of the crucial factors limiting the power capacity of high-power microwave (HPM) generators. In this paper, a waveguide cavity has been designed to study quantitatively the influence of temperature on high-gradient RF breakdown. The two planes of the waveguide cavity are divided into a strong-field side and a weak-field side with the feeding of microwave signals. The temperature of the strong-field side of the waveguide cavity can be adjusted from ambient temperature (25 °C) to 435 °C by loading a resistive wire heater. The breakdown threshold of the waveguide cavity decreases apparently with the increase in the temperature. The breakdown threshold at 408 °C is 751 kV/cm, which is about 150 kV/cm lower than that at ambient temperature. In addition, the higher the temperature, the more pronounced the pulse shortening. Under the same microwave power injection, the averaged pulse width of HPM after passing through the waveguide cavity at 408 °C is equal to 17.6 ns, shortened by about 1/3 compared to that at ambient temperature. The quantitative study of the influence of temperature on the RF breakdown provides a new guideline for exploring breakdown suppression methods in HPM generators.

Ultrasound diagnosis of congenital Morgagni hernias: Ten years of experience at two Chinese centers.

Morgagni hernias are rare anomalies that are easily misdiagnosed or missed. To summarize the ultrasound (US) imaging characteristics of Morgagni hernias through a comparison of imaging and surgical results. The records of children with Morgagni hernias who were hospitalized at two hospitals between January 2013 and November 2023 were retrospectively reviewed in terms of clinical findings, US features, and operative details. Between 2013 and 2023, we observed nine (five male and four female) children with Morgagni hernias. Upper abdominal scanning revealed a widening of the prehepatic space, with an abnormal channel extending from the xiphoid process to the right or left side of the thoracic cavity. The channel had intestinal duct and intestinal gas echoes. Hernia contents were found in the transverse colon (n = 6), the colon and small intestine (n = 2), and the colon and stomach (n = 1). Among the patients, seven had a right-sided lesion, two had a left-sided lesion, and all of them had hernial sacs. US imaging can accurately determine the location, extent, and content of Morgagni hernias. For suspected Morgagni hernias, we recommend performing sonographic screening first.

Comparative evaluation of efficacy of 2% lidocaine containing adrenaline with and without hyaluronidase in inferior alveolar nerve blocks for patients requiring bilateral mandibular extractions

AbstractPurposeTo evaluate and compare the efficacy of 2% lidocaine containing adrenaline with and without hyaluronidase in inferior alveolar nerve blocks for patients requiring bilateral mandibular extractions.Patients and MethodsThis was the split‐mouth study conducted on 26 patients requiring bilateral mandibular teeth extraction. All the patients were assigned randomly to one of the two groups: (i) 2% lignocaine HCl + 1:2,00,000 adrenaline + hyaluronidase (75 IU) solution will be administered on one side which is the experimental side and (ii) 2% lignocaine HCl + 1:2,00,000 adrenaline solution on the other side is control side. In the first session, the patients randomly received the inferior alveolar nerve block with or without hyaluronidase in one side of the oral cavity. One week later, the same patient received the other technique which was not received in the first session. We also evaluated the onset, duration and need of any supplementary anaesthesia in both the groups.ResultsComparison of VAS score in the control group (2.73 ± 0.724) and experimental group (3 ± 0.693) showed statistically insignificant results (p = 0.177). Whereas the onset of local anaesthesia showed a statistically significant difference between the two groups (p < 0.001) mean of control group (2.73 ± 0.47) and experimental group (1.15 ± 0.23). Comparison of duration of anaesthesia showed a statistically significant difference (p < 0.001) with the mean duration of the experimental group being higher (106 ± 7.94) than the control group (86.27 ± 3.90). Comparison for the need for supplementary anaesthesia showed no statistically significant difference between the two groups.ConclusionWe conclude that if hyaluronidase is used, better blocks with smaller volumes are produced. LAs with hyaluronidase have been shown to improve the quality and effectiveness of anaesthetic blocks and shorten the time it takes for anaesthesia to begin, accelerate the onset of akinesia and lessen the need for additional anaesthesia. It also increases the duration of anaesthesia.

Thermal energy storage system based on nanoparticle distribution optimisation for enhanced heat transfer

As a new type of heat transport medium with high efficiency and high heat transfer performance, nanofluids can effectively improve the heat transfer performance of thermal systems. In this paper, a lattice Boltzmann method is employed to propose a novel thermal storage system with optimised nanoparticle distribution using spacer-separated nano-enhanced PCM with spacer arrangement. The thermal energy storage units are separated by thermal insulation and heated by means of thermally conductive fluid channels. The effects of Rayleigh number, volume fraction and layout pattern are investigated. It is shown that the larger the Rayleigh number is, the more intense the reaction of the heat storage system is; it is concluded that the strong convection phenomenon in the upper left side region is more than that in the lower left side, and the volume fraction in the lower left side can be reduced to enhance the efficiency of this heat transfer in order to achieve a faster melting rate. The various distributions studied in this paper all have the effect of accelerating the melting rate to varying degrees compared to Type 1. The present study shows that increasing the volume fraction of phase change material in the upper left side of the square cavity has a promoting effect on the melting rate when compared to the lower side, and the larger the difference between the two, the better the effect is.

Development and safety study of a 3D printed middle turbinate splint

Adhesion of the middle turbinate to the lateral wall of the nasal cavity and synechia of the middle meatus are one of the common reasons for the failure of surgical interventions for chronic sinusitis. The use of specially shaped intranasal splints can solve the problem of preventing synechiae in the postoperative period. Many different devices and approaches have been proposed to prevent the development of this category of complications. This study proposes an anatomical version of the splint for the middle turbinate, developed using 3D computer modeling technologies followed by printing from a biocompatible elastic material on a Formlabs 3BL 3D printer. The shape and size of the splint were developed based on the analysis of computed tomography data of 50 adult patients. The safety of the developed device was studied in a group of 20 volunteers in whom the developed splint was installed on one side of the nasal cavity for 2 weeks after bilateral surgery. According to endoscopic examination and patient questionnaires, the developed splint did not cause local or systemic allergic reactions and did not create additional discomfort for the patient in the postoperative period. Installing a splint helped prevent the formation of synechiae. However, to determine clinical effectiveness, a study with a larger sample of patients is required.

Exo- or endo-1H-pyrazole metal coordination modulated by the polyamine chain length in [1 + 1] condensation azamacrocycles. Binuclear complexes with remarkable SOD activity.

The Cu2+ complexes of three [1 + 1] azacyclophane macrocycles having the 1H-pyrazole ring as the spacer and the pentaamine 1,5,8,11,15-pentaazadecane (L1) or hexaamines 1,5,8,12,15,19-hexaazanonadecane (L2) and 1,5,9,13,17,21-hexaazaheneicosane (L3) as bridges show endo- coordination of the pyrazolate bridge giving rise to discrete monomeric species. Previously reported pyrazolacyclophanes evidenced, however, exo-coordination with the formation of dimeric species of 2 : 2, 3 : 2 or even 4 : 2 Cu2+ : L stoichiometry. The complexes have been characterized in solution using potentiometric studies, UV-Vis spectroscopy, paramagnetic NMR, cyclic voltammetry and mass spectrometry. The measurements show that all three ligands have as many protonation steps in water as secondary amines are in the bridge, while they are able to form both mono- and binuclear Cu2+ species. The crystal structures of the complexes [Cu(HL1)Br]Br(1+x)(ClO4)(1-x)·yH2O (1) and [Cu2(H-1L2)Cl(ClO4)](ClO4)·H2O·C2H5OH (2) have been solved by X-ray diffraction studies. In 1 the metal ion lies at one side of the macrocyclic cavity being coordinated by one nitrogen of the pyrazolate moiety and the three consecutive nitrogen atoms of the polyamine bridge. The other nitrogen of the pyrazole ring is hydrogen-bonded to an amine group. In 2 the two metal ions are interconnected by a pyrazolate bis(monodentate) moiety and complete their coordination spheres with three amines and either a bromide or a perchlorate anion, which occupy the axial positions of distorted square pyramid geometries. Paramagnetic NMR studies of the binuclear complexes confirm the coordination pattern observed in the crystal structures. Cyclic voltamperommetry data show potentials within the adequate range to exhibit superoxide dismutase (SOD) activity. The IC50 values calculated by McCord-Fridovich enzymatic assays show that the binuclear Cu2+ complexes of L2 and L3 have SOD activities that rank amongst the highest ones reported so far.

Design and Experiment Investigation on Soft Grippers with Modular Variable Stiffness Structure.

Soft grippers have good adaptability and flexibility for grasping irregular or fragile objects, and to further enhance their stiffness, soft grippers with variable stiffness have been developed. However, existing soft grippers with variable stiffness have the disadvantages of complex structure and poor interchangeability. Here, a soft gripper with modular variable stiffness is proposed that has flexible Velcro embedded in the bottom layer of the soft actuator and one side of the variable stiffness cavity respectively, and both the general and variable stiffness grasping modes are achieved by separation or combination. First of all, according to the neo-Hookean model and the assumption of constant curvature, a free bending model of the soft actuator is established and optimal structural parameters of the soft actuator are obtained by the Genetic Algorithm. Then, influence of the driving pressure on the soft actuator stiffness is investigated, and a mathematical model of the variable stiffness is established. Finally, correctness of the statics model and the stiffness model were verified by experiments. Experimental results indicate that the proposed soft gripper with modular variable stiffness structure has excellent adaptability and stability to different objects, outstanding load bearing capacity, and stiffness adjustment capability.

Synergetic effect of magnetic field location, strength and orientation on heat transfer characteristics of brine-based hybrid nanofluid in rectangular confinement

The hybrid nanofluid emergence is presently receiving untold research attention as an improved cooling medium. This paper presents an investigation into the free convection thermal transport performance of brine (ethylene glycol-deionized water (60:40 vol%)-based hybrid ferrofluid (Fe2O3-Al2O3) (BBHF) in a rectangular cavity under steady-state conditions with and without magnetic inducement. The synergetic effect of different magnetic field orientations and intensities imposed on the various walls of the confinement and their influence on the heat transfer characteristics of BBHF was examined. At volume concentrations of 0.05–0.40 %, the BBHF was formulated and characterised for its viscosity, stability, morphology, and thermal conductivity. Without a magnetic stimulus, the average Nusselt number, heat transfer rate, and coefficient of heat transfer of 0.05–0.2 vol% BBHF samples were improved relative to the brine. At a cavity temperature gradient of 35 °C using 0.05 vol% BBHF, a peak thermal transport enhancement of 10.09 % was observed when compared with the brine. With 0.05 vol% BBHF, the vertical positioning of the magnetic stimulus on the cavity side wall was noticed to yield maximum improvement of heat transfer (4.3 %). An increment in the strength of the magnetic stimulus from 4.89 mT to 13.00 mT enhanced thermal transport by >15 %, which subsequently deteriorated when increased to 21.95 mT for all the studied magnetic stimulus arrangements. In addition, correlations were proposed to predict the Nusselt number, thermal conductivity, and viscosity of the BBHFs. The employment of hybrid nanoparticles, magnetic stimulus, and different arrangements of the magnetic stimulus was observed to amplify the heat transfer of BBHFs in the cavity which is of practical and engineering benefit.

High sensitivity detection of ethanol solution based on waveguide resonant cavity combined with metamaterials

In this article, a novel methods of ethanol solution detection based on the waveguide resonant cavity and metamaterial, is proposed. Different from the traditional detection methods, our proposed technique has the advantages of alleviating the negative effects of the volatility and high loss of ethanol, and result in the improvement of sensitivity. By opening a gap on the narrow side of the resonant cavity properly, the measured object, i.e., the ethanol solution, can flow into the cavity, without the adopting of additional tube as the fluid channel. Moreover, since the constant volume and metallic shield of the cavity, the test setup can keep stable, which is advisable for the accurate detection under complex environment. In order to enhance the interaction between electromagnetic waves (EMWs) and ethanol solution, the metamaterial structure of the split-ring resonant (SRR) is employed and integrated with the resonant cavity. Multilayer medium theory is developed to analyze the propagation of the EMWs and optimize the performance. The proposed method can detect the variation of ethanol concentration from 0 % to 100 %, by changing the resonant frequency from 1.56 GHz to 2.44 GHz (0.88 GHz shift), exhibiting a sensitivity of 0.8 % and a maximum error of only 1.4 %. The simulation and test results are consistent, demonstrating the feasibility of using the waveguide resonant cavity and metamaterial for highly sensitive and accurate detection of ethanol.

Research on influencing factors of oil film temperature field characteristics for adaptive hydrostatic thrust bearing

Adaptive hydrostatic thrust bearing represents a mechatronic answer to the fast-growing industrial needs of high-performance rotary machineries. The aim of this research is to study the influencing factors of the temperature field characteristics of the adaptive hydrostatic thrust bearing, such as rotational speed, load, viscosity, and inlet flow rate. The temperature rise equation of the micro-gap oil film is derived, and a three-dimensional model of micro-gap oil film is established. Finite Volume Method and ANSYS FLUENT are used to explore the influence factors of the temperature rise of the micro-gap oil film based on the principle of Computational Fluid Dynamic. The results show that temperature rise on the downstream side of the oil cavity is higher than that on the countercurrent side, and the temperature rise on the edge of the outer oil sealing edge is higher than that on the inner oil sealing edge. The rotational speed has the greatest impact on the oil film temperature rise, followed by viscosity, inlet flow rate, and then load. The increment of oil film temperature rise with the load less than 16 t is higher than the increment of oil film temperature rise with the load greater than 16 t. When the rotational speed is lower than 80 rpm, the temperature rise of the oil film increases faster with the increase of the rotational speed than when the rotation speed is above 80 rpm. The inlet flow rate increases, the maximum temperature and average temperature rise of the oil film decreases, but there is little variation. The maximum temperature and average temperature rise increase with the increase of viscosity, and the greater the viscosity, the more obvious nonlinear.

Correlation of Upper Lateral Cartilage Collapse and Nasal Septal Deviation

Background and Objectives: This study aimed to elucidate the relationship between nasal septal deviation (NSD) and upper lateral cartilage (ULC) collapse.Methods: We conducted a retrospective review of 142 paranasal sinus computed tomography scans from patients who had undergone septoplasty due to confirmed NSD. The ULC angle was measured on both the narrow and wide sides of the nasal cavities, and these measurements were compared to evaluate the extent of ULC collapse in relation to the degree of NSD and patient age. The correlation between the degree of NSD and the degree of ULC collapse was also analyzed.Results: The mean ULC angle was found to be 13.4°±2.7° on the narrow side and 14.3°±2.7° on the wide side, with a statistically significant difference between the two (p<0.001). When comparing caudal and non-caudal NSD patients, there was no significant difference in the degree of ULC on either side (p=0.166). When comparing the ULC angle between two age groups (≥50 vs. <50 years), the difference in ULC angles was significantly greater in the group of patients aged under 50 years (0.3°±3.8° vs. 1.1°±2.2°, p=0.014). There was a significant positive correlation between the degree of ULC collapse and the degree of septal deviation (r=0.214, p=0.01).Conclusion: NSD was associated with ULC collapse on the narrow side and a narrow internal nasal valve area. This result indicates that clinicians should check for concomitant ULC collapse in patients with NSD.

Types of the nasal septum deviations and their influence on the state of mucociliary clearance of the nasal cavity in patients with postnasal obstruction syndrome

The flow of nasal secretions into the pharynx and larynx manifests itself differently throughout the day. At night, this mucus flows into the larynx, irritates reflexogenic zones and causes coughing, and during the day these complaints are less noticeable, due to involuntary swallowing of secretions. We hypothesized that different types of nasal septum deviations may affect mucociliary clearance and, as a result, lead to postnasal drip syndrome. However, we did not find any studies in the literature that examined the effect of types of nasal septum deviation (NSD) on mucociliary clearance (MCC). Therefore, in our study, we evaluated the effect of the types of nasal septum deviations on MCC. The aim of the study. To investigate the activity of mucociliary clearance of the mucous membrane of the nasal cavity in patients with different types of NSD. Materials and methods. 100 patients were investigated. All patients underwent an endoscopic examination of the nasal cavity, a ST scan of the nasal cavity, and a saccharin test. The results. The analysis made it possible to reveal that in most patients with type 2 deviation of the nasal septum with the presence of a unilateral caudal ridge, which cuts into the middle turbinate, there is PNDS. At the same time, while the average ST time of the concave side of the nasal mucosa in patients with type 1 was almost unchanged, it was significantly longer in patients with type 2 (P=0,02). Therefore, in this study, the ST indicator in min. was longer on the concave side of the nasal cavity than on the convex side. Conclusions. Our research has shown that nasal septum deviation reduces nasal mucociliary activity, and this effect can be easily assessed using the saccharin test. According to our observations and research results, it was the 2nd and 3rd types of deviation that significantly disturbed the architecture of the nasal cavity, due to the presence of contralateral vertical deviation of the nasal septum, contralateral hyperplasia of the nasal turbinates, and contralateral conchobulosis. And, as a result, led to a decrease in mucociliary clearance

Shared and distinguishing phenotypic characteristics of filamin c and desmoplakin cardiomyopathy

Abstract Background Rare truncating variants in the genes Filamin C (FLNC) and Desmoplakin (DSP) are increasingly recognised causes of Dilated Cardiomyopathy and Arrhythmogenic Cardiomyopathy (1,2). A direct comparison of both genotypes is needed to aid in subclassification and genotype-specific risk modelling. Purpose We sought to identify shared and distinguishing clinical characteristics and imaging phenotypes between FLNC and DSP cardiomyopathy. Methods 41 patients with ‘pathogenic’ or ‘likely pathogenic’ FLNC or DSP variants by American College of Medical Genetics (ACMG) criteria were identified from a tertiary centre cardiovascular genetics laboratory. Clinical, genetic and imaging data were compiled. Continuous variables are presented as median [IQR] or mean±SD and analysed by nonparametric Mann Whitney U or t-test. Categorical variables were analysed by Chi-Squared or Fisher’s exact test. Results FLNC and DSP cohorts included a similar proportion of patients with truncating variants (91% vs 100%) and female sex (12/21, 57% vs 13/20, 65%). FLNC patients were younger (median age 30 [13-51] vs 57 [41-65] years, p<0.0008) and more likely to present with sustained ventricular arrhythmia (5/21 24% vs 3/20, 15%) (Table 1). Acute myocarditis episodes were exclusively linked to DSP cardiomyopathy (4/20, 20%) with no association to FLNC (0/21, 0%, p<0.05). FLNC cardiomyopathy patients had normal left ventricular (LV) systolic function (LVEF 57±9% SD vs 46±13% DSP, p<0.03) and normal left ventricular cavity side (mean indexed LV end diastolic volume (EDV) 85±12 vs 112±26ml/m2 DSP, p<0.02) (Table 2). Both FLNC and DSP cause exclusive left ventricular or biventricular late gadolinium enhancement (75% Vs 82%) on cardiac magnetic resonance imaging (MRI). Fibrosis was predominantly in a subepicardial distribution in both cohorts (66% FLNC vs 57% DSP). In FLNC, circumferential fibrosis was the most frequent pattern of distribution (5/9, 55%), whereas in DSP inferior and lateral wall fibrosis was the predominant feature (8/14, 57%). There were no cases of isolated RV involvement and no cases fulfilled ‘definite’ ARVC taskforce diagnostic criteria. Over a follow up of median 45months, there was no significant difference in the proportion of FLNC and DSP patients experiencing a composite end point of LVAD implantation, heart transplant, aborted sudden cardiac death or mortality (7/21, 33% FLNC Vs 7/20, 29% DSP p>0.99). Conclusion Normal systolic function with marked circumferential fibrosis is the predominant feature of FLNC cardiomyopathy whereas mild LV dilatation, mild systolic impairment and inferolateral fibrosis are more frequent in DSP cardiomyopathy. Myocarditis episodes are a distinguishing feature of DSP cardiomyopathy, suggesting a different underlying molecular mechanism driven by inflammation. The overall clinical trajectory of FLNC and DSP cardiomyopathy patients are comparable.

ON CONTACT PROBLEMS FOR TWO STAMPS AND A NEW TYPE OF CRACK MODEL

In this work, for the first time, an exact solution of the contact problem of interaction with a multilayer base of two semi-infinite stamps, the ends of which are parallel to each other, is constructed. Stamps are assumed to be absolutely rigid, and the distance between them can have any finite value. The task is an important stage in the algorithm for constructing models of a new type of crack in materials of different rheologies. The mechanism of destruction of the medium by cracks of a new type is radically different from the mechanism of destruction of the medium by Griffiths cracks, and has so far been poorly studied. Griffiths formed his cracks with a smooth border as a result of compression from the sides of an elliptical cavity in the plate. Cracks of a new type have a piecewise smooth border, resulting from the replacement of an ellipse with a rectangle compressed from the sides. The problem considered in the article can be considered as the result of the formation of a new type of crack with absolutely rigid banks and deformable lower boundary. Thanks to it, after the solution, it becomes possible to switch to deformable stamps and a crack of a new type in the rheological medium. The solution of this problem turned out to be possible due to the construction of exact solutions of the Wiener–Hopf integral equations on a finite segment. The paper shows how the solution of one of the previously unsolved problems allows us to investigate and solve exactly other problems, to identify previously unknown properties and resonances. As a result of constructing an exact solution to the problem, the fact that the solution of dynamic contact problems for stamp systems is not unique was confirmed and a dispersion equation for finding resonant frequencies was constructed.

Evaluation of Fracture Strength after Repair of Cervical External Resorption Cavities with Different Materials

IntroductionThe aim was to evaluate the stress distributions on dentin and repair materials caused by static force applied to teeth, with cervical external root resorption (CER) after repair with different materials using finite element analysis. MethodsThis study was performed with the 3-dimensional finite element analysis method. Access cavity, root canal cavity dimensions, and supporting tissues other than cementum were modeled in the maxillary central tooth. The CER cavity was created on the labial side of the tooth model. The coronal side of the resorption cavity was restored with composite, and the radicular side with different materials (MTA, Biodentine, BioAggregate, calcium-enriched cement [CEM], glass ionomer cement [GIC], and resin-modified glass ionomer cement [RMGIC]). A static force of 300 N was applied to the palatal surface of the crown at an angle of 135° to the long axis of the tooth. The stress distributions in dentin and repair materials were analyzed. ResultsThe highest stress in dentin was seen in the fFigmodel with unrepaired CER. In the models repaired with MTA, GIC, and RMGIC, von Mises stress values in dentin were greater than for repairs with Biodentine, BioAggregate, and CEM materials. The von Mises stress on the repair materials applied to the root were highest for the BioAggregate material. This was followed by CEM, Biodentine, MTA, RMGIC, and GIC materials, respectively. ConclusionThe repair of CER in the tooth significantly decreased the stress values in dentin. Biodentine, BioAggregate, and CEM absorbed more force and caused less stress to be transmitted to dentin compared to MTA, GIC, and RMGIC.

Supernovae Origin for the Low-latitude Intermediate-velocity Arch and the North Celestial Pole Loop

Supernova explosions attributed to the unseen companion in several binary systems identified by the Third Gaia Data Release (Gaia DR3) may be responsible for a number of well-known and well-studied features in the radio sky, including the low-latitude intermediate-velocity (LLIV) arch and the north celestial pole (NCP) loop. Slices from the longitude–latitude–velocity data cube of the λ-21 cm Galactic neutral hydrogen HI4PI survey show multiple signatures of an expanding shell. The source of this expansion, which includes the LLIV arch on the approaching side, may be the neutron star candidate in the Gaia DR3 1093757200530267520 binary. If we make the simplifying assumptions that the expansion of the cavity is uniform and spherically symmetric, then the explosion took place about 700,000 yr ago. The momentum is in reasonable agreement with recent model estimates for a supernova this old. The H i on the receding side of this cavity is interacting with the gas approaching us on the near side of a second cavity. The NCP loop appears to be located at the intersection of these two expanding features. The neutron star candidate in the Gaia DR3 1144019690966028928 binary may be (in part) responsible for this cavity. Explosions from other candidates may account for the observed elongation along the line of sight of this second cavity. We can use the primary star in these binaries to anchor the distances to the LLIV arch and NCP loop, which are ∼167 and ∼220 pc, respectively.

Aluminum Foam Sandwich: Pore Evolution Mechanism Investigation and Engineering Preparing Optimization.

This paper employs an innovative investigation approach to study pore evolution in Al-Si-Mg-Cu alloy within aluminum foam sandwiches (AFS) by integrating data from heating-expansion ratio curves, in situ observation of synchronous radiation, and microscopic analysis of the matrix's microstructure at different stages. Additionally, the cavity design and plate type control for large-scale AFS production are explored. Findings categorize the precursor heating into three stages: rapid heating, solid-liquid transition, and stable foaming. During solid-liquid transition, the expansion rate experiences a sudden drop, associated with pore nucleation and edge cracking of precursors. Pores nucleate as elongated crack-like structures along the rolling direction, guided by the Mg-enriched regions. In stable foaming, these pores evolve, become spherical, and the matrix rapidly expands. Using square tubes for sealing on the preform cavity sides creates a dense edge zone during rolling, halting crack propagation into the powder core. Adopting edge sealing during foaming mitigates boundary effects, thereby improving AFS panel flatness.

Active anterior rhinomanometry: A study on nasal airway resistance, paradoxical reactions to decongestion, and repeatability in healthy subjects.

Anterior active rhinomanometry (AAR) is widely used in Swedish routine clinical practice to decide if septoplasty is necessary. The scientific basis for the method needs to be strengthened. Therefore, the aims were to evaluate nasal airway resistance (NAR), paradoxical reactions to pharmacological decongestion, and test-retest characteristics of the Rhino-Comp® AAR in healthy subjects. A prospective longitudinal design was used. AAR was performed before and after decongestion at baseline and after ≥6 months on 60 healthy volunteers. The relationships between NAR, height, weight, BMI, sex, and allergic rhinitis were evaluated by regression analyses. Descriptive statistics were used to evaluate paradoxical reactions. Test-retest and repeatability characteristics were evaluated with intra-class coefficients (ICC), Cronbach's α, and standard error of measurement. No statistically significant differences were found between genders or nasal cavity sides. NAR was statistically significantly related to height. Short- and long-term test-retest characteristics were good with ICC and Cronbach's α > .75. The minimal significant difference in NAR Log10V2 values between the two measurements was 0.11 and 0.09 (long- and short-term). Paradoxical reactions to pharmacological decongestion were rare, mostly weak, and not evidently reproducible. In this study, we report reference data for healthy subjects, test-retest capabilities, and the minimal relevant difference between two measurements for the Rhino-Comp® AAR, information that is vital and necessary for the appropriate use of AAR in clinical practice. An effective method for pharmacological decongestion is described and recommended for future studies and clinical practice. Paradoxical reactions to pharmacological decongestants exist but maybe without clinical significance. NA.

Alternative Method of Surgical Treatment of Post-Infarction Left Ventricular Free Wall Rupture. Case Report

Acute myocardial infarction (AMI) is one of the causes of death in developed countries, despite the latest medical technologies. AMI is usually accompanied by numerous fatal complications. One of these complications is left ventricular free wall rupture (LVFWR). Myocardial rupture after AMI can occur from 1 day to 3 weeks after the infarction. Most ruptures occur 3-5 days after a heart attack. Left ventricular free wall rupture requires only emergency surgical intervention, which in most cases consists in applying U-shaped sutures or wrapping sutures using Teflon patch.
 The aim. To demonstrate an example of alternative surgical tactics and intraoperative management of a patient with myocardial infarction complicated by rupture of the free wall of the heart with the transition to cardiogenic shock.
 Case report. We presented the clinical case of patient V., 72 years old, who was delivered by ambulance on January 10, 2023 to the intensive care department of the National Amosov Institute of Cardiovascular Surgery (Kyiv, Ukraine). Main diagnosis: ischemic heart disease, acute coronary syndrome with ST-elevation myocardial infarction, cardiogenic shock.
 Conclusion. The only effective method of treatment of rupture of the free wall of the heart is surgical intervention. Using a sandwich patch with resection of necrotic areas of the myocardium and U-shaped sutures with Teflon patch passed from the side of the left ventricular cavity through the myocardium in the peri-infarct zone and through a patch from a vascular prosthesis allows hermetically sew up the LVFWR.