Siberian Federal District Research Articles

Состояние отечественной отрасли козоводства на современном этапе развития России

The article analyzes the state of the goat breeding industry in Russia from 2007 to 2022. Based on official data from the Federal State Statistics Service and data from the All-Russian Research Institute of Breeding, presented in the public domain, an assessment of the state of the goat breeding industry in Russia was carried out and the main trends and patterns were identified. As part of the study, it was revealed that goat breeding in Russia is mainly concentrated in small forms of farming and currently there are no prospects for scalability, while the number of goats is decreasing annually. The leader among federal districts in terms of livestock is the Siberian Federal District, and among the subjects of the Federation the undisputed leader is the Republic of Tyva. Dairy goat farming ranks third in the world in milk production, behind cows and buffaloes. In Russia, there is a clear trend towards increasing milk production. The leader in goat milk production is the Leningrad region. The analysis of modern domestic goat breeding made it possible to formulate the main problems that impede the effective development of the industry in the country and outline possible ways to solve them.

Hantavirus Infections: Review of the Epidemiological Situation around the World. Analysis of the Epidemiological Situation on Hemorrhagic Fever with Renal Syndrome in the Russian Federation in 2023 and Forecast of Its Development for 2024

The paper describes the epidemiological situation in the countries of the world in terms of the incidence of Hantavirus diseases. The results of an epidemiological analysis of the incidence of hemorrhagic fever with renal syndrome (HFRS) in the Russian Federation in 2023 by federal districts are presented and a forecast for 2024 is made. In 2023, 5 093 cases of HFRS were registered in the Russian Federation (3.47 per 100 thousand population). The incidence was reported in 7 out of 8 federal districts of the country. The age structure was dominated by people in the 30–59 age category (65.7 %); 247 cases of the disease were noted among children under 17 years of age. The proportion of the male population was 70.3 %. 63.2 % of the total number of cases was registered among the urban residents. The mortality rate was at the level of 0.49 % – 25 lethal outcomes. Analysis of the data has revealed a decrease in the incidence of HFRS in Russia by 27.2 % as compared to the previous year. However, the data from epizootiological monitoring and the results of laboratory research of field material indicate a continuing tense situation in the country as a whole. In a number of regions, a high risk of complications of the epidemiological situation is predicted (mainly, in the constituent entities of the Volga and Central Federal Districts). Moderate risks of developing local complications of the epidemiological situation at the level of long-term average morbidity are expected to be realized in the entities of the Northwestern, Ural and Far Eastern Federal Districts. Sporadic cases of the disease in the territory of the Southern Federal District are not excluded. The aggravation of the situation on HFRS in the territory of the North-Caucasian and Siberian Federal Districts is not anticipated in 2024.

Regional innovations influence on the ecological footprint of the Russian Federation territories: case of the Siberia and Volga regions

Relevance. Ensuring the development of the country regions on the principles of environmental and economic balance, taking into account the national development goals of Russia until 2030.This article models the relationship between economic development and environmental progress. The relationship between investment in innovation and uncontrolled emissions in certain regions of Russia in the period from 2010 to 2022 is explored. Aim. To study the intensity of innovation influence on the ecological footprint, as well as the efficiency of functioning of environmental-innovative activities, in regions of different types using the example of the Siberian Federal District and the Volga Federal District. Methods. Panel regression with fixed effects, correlation analysis, DEA method, cluster analysis, analysis of variance. Results and conclusions. Using the example of 24 Russian regions, it is shown that the intensity increase of the research and development of regional companies does not always lead to an increase in the environmental footprint and an increase in emissions intensity. The obtained results indicate that the economic and environmental dimensions of sustainable development contradict each other and suggest that regional governments should consider the negative environmental externalities of economic development when designing policies to promote regional growth. It is noted that the growth of investments in the research and development of more developed regions reduce the emissions intensity level. Large industrial centers of Siberia and the Volga regions are investing in innovation to increase the intensity of emissions. The hypothesis about the high degree of the economic space heterogeneity in terms of the influence of the research and development intensity of regional companies on the degree of environmental pollution in the regions of the Russian Federation is confirmed. The necessity is emphasized to take into account the regional specifics of the industrial structure of the economy. A highly significant heterogeneity was revealed in the efficiency of environmental-innovative activities functioning in the regions of the Siberian Federal District and Volga Federal District. Moreover, the effectiveness of environmental-innovative activities of the regions is insignificantly correlated with the identified imbalance of this activity.

Стратегический анализ реализации пациент-ориентированного подхода к развитию здравоохранения Кузбасса

Achieving the strategic goals of the Russian Federation for preserving the population and ensuring the health and well-being of people requires an effective health care system that can provide necessary medical services and technologies and systematically train residents in healthy lifestyle and disease prevention. 
 This necessitates a transition to patient-oriented medicine based on strategizing, which will ensure the coordination of federal, departmental and regional programs aimed at improving the medical care quality and the population health. The article analyses legislative, regulatory, organizational documents and statistical data at the federal, regional and departmental levels. The authors perform analysis of healthcare statistical indicators in the Siberian Federal District and its subjects in dynamics; OTSW analysis on the strategizing methodology; comparative analysis of long-term healthcare development goals. The expediency of applying strategic planning and management in the transition to patient-oriented medicine is established; interrelations between strategies of different levels are discovered; region’s strategic objectives for the healthcare sector transformation and the conditions for their implementation effectiveness are defined. The authors consider possibilities of implementing a strategy for the patient-oriented medicine development in Kuzbass on the basis of region’s strengths, identify the threats and risks of not achieving strategic objectives and formulate the proposals for their reduction. The article confirms the importance of strategies’ coherence and proactivity within the appropriate priorities; argues the potential for the patient-oriented medicine development in Kuzbass.

Федеральные особо охраняемые природные территории Алтайского края: современное состояние и перспективы развития

Одна из важнейших глобальных проблем современности — сохранение природной среды. Гарантией эффективного сохранения природно-территориальных комплексов региона является создание сети особо охраняемых природных территорий (ООПТ), которая обладает репрезентативностью по отношению к ландшафтному и биологическому разнообразию. Также известно, что более строгий режим охраны, который характерен для заповедников и национальных парков, способствует успешной реализации задач охраны природы. В статье рассмотрено современное состояние ООПТ федерального значения Алтайского края — Государственного природного заповедника «Тигирекский» и Национального парка «Салаир», а также перспективы создания проектируемого Национального парка «Горная Колывань». Показано, что действующие и проектируемая федеральные ООПТ в крае располагаются только лишь в его горной части, а природные комплексы равнинной части края, которые также обладают большой природоохранной ценностью, охраняются лишь режимами заказников и памятников природы регионального значения. Площадь федеральных ООПТ за последнее время в крае увеличена с 0,25 до 1,5 % от площади региона, что является одним из самых низких показателей по регионам Сибирского Федерального округа. Создание Национального парка «Горная Колывань» играет большую роль в сохранении природного разнообразияи историко-культурного наследия Северо-Западного Алтая, позволяет объединить разрозненные региональные ООПТ в единое целое на организационном уровне. В случае создания данной ООПТ и придания охранной зоне заповедника федерального статуса доля федеральных охраняемых территорий возрастет до 2,5 % от площади края.

Occurrence in sick animals and genetic heterogeneity of Siberian isolates of bovine respiratory syncytial virus (Pneumoviridae: <i>Orthopneumovirus</i>; BRSV) identified in the territories of the Ural, Siberian Federal District and the Republic of Kazakhstan

Introduction. Bovine respiratory syncytial virus (Pneumoviridae: Orthornavirae, Orthopneumovirus; Bovine orthopneumovirus, Bovine respiratory syncytial virus, BRSV) is one of causative agents of respiratory diseases in animals. The study of the occurrence and genetic diversity of this pathogen is of particular importance.
 Objective. To study the frequency of virus in animals using RT-PCR and genetic heterogeneity of isolates based on determining the complete nucleotide sequence of glycoprotein G gene.
 Materials and methods. A 381-bp region of glycoprotein F gene was used for identification of virus genome, while complete nucleotide sequences of G gene were used for phylogenetic analysis. Phylogenetic trees were constructed using the maximum likelihood method in MEGA 7.0 software.
 Results. During outbreaks of respiratory diseases, BRSV RNA was detected in animals of all ages in samples of lungs, nasal secretions, pulmonary lymph nodes. Complete nucleotide sequences of glycoprotein G gene, 771 bp in length were obtained for five isolates and 789 bp in length ‒ for two isolates. Nucleotide similarity between them was 87–100%. Phylogenetic analysis assigned the isolates to subgroups II and III, each of which included two isolates. A separate clade formed by K18 isolate from animals imported from Canada and sequences from vaccines containing the attenuated «375» strain.
 Conclusion. The virus genome was identified in cows and heifers (20.0 and 14.3%), in calves up 1 month of age (3.05%), and in calves from 1 to 6 months of age (6.7%). Complete G gene nucleotide sequence analysis is a useful tool for studying the molecular epidemiology of BRSV on particular territories.

Inflation on agricultural products and food stuff as a threat to food security (Based on the materials of the Siberian Federal District and the Krasnoyarsk Krai)

Subject. The article addresses the issues of economic availability of food for the population. Objectives. The purpose is to develop measures to minimize negative effects of inflation and ensure sustainable access of the population to high-quality and affordable food products. Methods. The study employs methods of statistical analysis. Results. Measures to increase the affordability of food should include: regulating food prices and targeting food inflation, ensuring outstripping or commensurate with the rate of inflation growth of incomes of the population, improving the quality and accessibility of food stuff for low-income citizens. Conclusions. Despite the growth of incomes of the population, food inflationary dynamics reduces the level of economic affordability of food products in the Siberian Federal District as a whole and in certain regions of Russia.

The Biological Active Substances of Taraxacum officinale and Arctium lappa from the Siberian Federal District.

Currently, scientists are increasingly focusing on utilizing the natural flora of the planet to search for and isolate individual bioactive substances that prevent various diseases, contribute to increased life expectancy, and affect all major life-supporting systems in the human body. This study describes the examination of the composition of plant raw materials from the Siberian Federal District. The research focuses on plant specimens from the root parts of Taraxacum officinale and Arctium lappa, collected in the Kemerovo region. The study determines the contents of the water-soluble vitamins B and C in the research subjects. The investigation includes assessing antioxidant properties, antimicrobial activity, and flavonoid content in extracts based on plant raw materials. All samples show a high percentage of antioxidant activity, with the highest antioxidant activity for T. officinale at 85.51 and that for A. lappa at 88.97. The results indicate low antimicrobial activity against Escherichia coli (growth inhibition zone up to 15.5 mm). Plant extracts contain significant amounts of B-group vitamins, with pyridoxine in T. officinale (156.40 μg/mL) and thiamine (46.20 μg/mL) and pyridoxine (357.10 μg/mL) in Arctium lappa. Flavonoids (rutin and quercetin) are identified in T. officinale and A. lappa extracts based on the study results.

Improving the quality of financial management in the public administration sector as an essential factor in ensuring the economic security of regions (using the example of the Siberian Federal District)

Improving the quality of financial management in the public administration sector as an essential factor in ensuring the economic security of regions (using the example of the Siberian Federal District)

Problems of identification and elimination of objects of accumulated environmental damage in the Russian Federation

The article discusses the problems of identifying and eliminating objects of accumulated environmental damage in the Russian Federation. In the 20th century, the Soviet Union paid almost no attention to the management of production and consumption waste. This has led to widespread accumulation of waste in dumps, tailings dumps, sludge reservoirs, sludge pads and other industrial facilities. The situation began to change in the early 90s, when, under the auspices of the State Committee for Ecology of the Russian Federation, comprehensive programs for the management of production and consumption waste began to be developed in some regions of the country. But after the liquidation of the State Committee for Ecology of the Russian Federation in 2000, this work practically stopped. We returned to this issue only in the 2000s, when the Decree of the Government of the Russian Federation No. 455 of April 13, 2017 approved the Rules for maintaining the State Register of Objects of Accumulated Environmental Damage. The analysis showed that at the beginning of 2023, 683 objects were included in the register of the Russian Federation. Of these, only 13,3 % were liquidated. The largest number of objects included in the register was in the Siberian Federal District — 185, but not a single object in this district was liquidated. The largest number of liquidated objects, both in physical quantity and in percentage, was in the North Caucasian Federal District — 51 objects (56,0 % of the total number of liquidated objects and 62,2 % of those identified in this district). It has been suggested that it is possible that the procedure for registration of objects for inclusion in the register is quite complicated, which does not allow it to be carried out quickly enough. There is also no uniform nomenclature in the names of objects, which significantly complicates the analysis of the current situation.

Analysis of long-term dynamics of morbidity by the method of complex assessment at different territorial levels

BACKGROUND: A comparative epidemiological analysis of the primary incidence of tuberculosis was performed using its standard approach with a generalized indicator that considers the main statistical criteria for incidence. The “sensitivity” of the method may vary depending on the population from analyzed territories.
 AIM: This study aimed to perform a comparative assessment of the epidemiology of tuberculosis (TB) in different territories based on the standard incidence rate and modified method of its integral assessment.
 MATERIALS AND METHODS: A retrospective study of the dynamics of the incidence of tuberculosis in the total population from the federal districts (FD) of Russia and participants from the Siberian Federal District (SFD) and urban municipalities of the Irkutsk Region (a structural unit of the SFD) between 2005 and 2019 was performed. Based on the obtained integral indicators, a generalized visibility coefficient was calculated.
 RESULTS: A significant decrease in the incidence of TB was found in all patients from FD and SFD participants. Assessment of the average long-term incidence rates showed that the maximum discrepancy between ranking places was inversely proportional to the size of the studied territories: 1.5 positions, at the level of the FD; two positions, at the level of regional formations; and five positions, at the level of urban settlements.
 CONCLUSIONS: The integral assessment method can be used in the primary analysis of morbidity in all types of infectious and noninfectious pathologies. The generalized morbidity criterion expands the informative possibilities of the standard indicator, contributes to the substantiation of risk areas at the initial stages of epidemiological analysis, and responds more “sensitively” to changes in the epidemiological situation in relatively small areas.

State and prospects of external economic activity in Russian horse breeding in 2015–2023

The article examines the dynamics of export and import indicators of horse breeding products (in the category of goods “Live horses”) from 2015 to 2022, both in absolute and monetary terms, including taking into account the categories of breeding and use animals. For the first time, the foreign trade balance of the horse breeding industry in 2019–2022 has been analyzed, and the prospects for domestic and foreign markets for the products of Russian horse breeding farms have been assessed. It has been established that the export flows of the eastern regions of the country, and primarily the Trans-Baikal Territory, the Republic of Tyva, the Altai Territory and the Altai Republic, are focused primarily on the Republic of Kazakhstan, which makes commercial farms for the production of horses for meat production in the Siberian Federal District dependent on the political situation in Central Asia and the general state of veterinary well-being of the region. The ban on the export of horses classified as luxury goods from the European Union, introduced as part of a package of anti-Russian sanctions, affected the import of breeding and use animals, significantly limiting the opportunities for domestic consumers focused on trained horses. The state program for the development of horse breeding in the Republic of Uzbekistan may influence the increase in demand for products from enterprises involved in breeding riding horses.

Analysis of the Causes and Conditions for the Formation of a High Incidence of Acute Respiratory Infections (ARI) in the Population of the Altai Krai (Part 1. Features of Long-Term and Intra-Annual Dynamics of ARI Incidence in 2011–2021)

Relevance. The Altai Krai (AK) is among the least prosperous subjects of the Russian Federation in terms of the incidence of acute respiratory infections (ARI).Aim: to analyze the causes and conditions for the formation of a high incidence of ARI among the population of the Altai Krai based on an assessment of the long-term and intra-annual dynamics of the epidemic process in 2011–2021.Materials and methods. In the course of a retrospective epidemiological study according to the annual forms No. 2 of the state statistical observation (SOS) for 2011-2021 a comparative analysis of the incidence of ARI and community-acquired pneumonia (CAP) in various groups of the population of the AK, the Siberian federal district (SFD) and the population of the Russian Federation as a whole was carried out. Data for 2020–2021 («covid» period) was analyzed separately in comparison with the precovid period of 2011–2019. The intra-annual dynamics of the incidence of ARI and CAP in the AK were studied using the method of trend-seasonal decomposition according to the monthly forms No. 2 of the SOS.Results and discussion. It is established that in 2011–2021. the epidemic process of ARI in the AK was characterized by a higher level and rate of increase in the incidence of all population groups (adults and children, urban and rural) compared to the all-Russian and average for the Siberian Federal District; a higher proportion of children in the overall structure of ARI cases, despite the fact that the proportion of the child population did not exceed (or was even less) than in other regions; no decrease in the incidence of ARI in children in the period 2020–2021; the presence of a trend towards an increase in the incidence of ARI in both urban and rural residents in the pre-covid period; higher incidence in the rural population in 2011–2019 compared to the whole of the Russian Federation or the Siberian Federal District. A less pronounced role of the seasonal component in the registration of CAP was revealed, in comparison with ARI. In some years, an increase in the registration of CAP was observed in the spring-summer period. For 2020-2021 there was a close coincidence of the curves of the intra-annual dynamics of the registered incidence of ARI and COVID-19 among the general population, CAP and COVID-19.Conclusion. The obtained results indicate the need to study the possible impact of environmental factors, as well as the shortcomings of the etiological interpretation and differential diagnosis of some natural focal and zoonotic infections that occur with fever and respiratory symptoms on the formation of a high incidence of ARI in the Altai Territory.

Genetic structure and drug resistance of <i>Mycobacterium tuberculosis</i> strains in the Kemerovo Region — Kuzbass

Background. Kemerovo Region has a high burden of tuberculosis (TB) with incidence rates twice the national average. The circulating variants of Mycobacterium tuberculosis significantly influence the TB epidemic process. Screening of epidemically significant variants of the pathogen in areas with a high burden of TB underlies epidemiological diagnosis and is necessary for the development of effective prevention measures. However, the population structure of M. tuberculosis in the Kemerovo Region — Kuzbass is poorly understood.
 Aims: to study genetic heterogeneity and phenotypic resistance to anti-tuberculosis drugs of M. tuberculosis strains in the Kemerovo Region.
 Materials and methods. The MIRU-VNTR genotyping of 163 M. tuberculosis strains isolated from TB patients in the Kemerovo Region in March–October 2022 was carried out. Cultivation of M. tuberculosis, drug susceptibility testing, and isolation of genomic DNA were carried out by standard methods. Genotypic identification was performed using MIRU-VNTR (24 loci) typing. In parallel, express genotyping was carried out: identification of isolates of the Beijing genotype (by RD105/207) and non-Beijing; subtyping Beijing using real-time PCR tests for detection of Central Asian Russian and B0/W148; identification of the non-Beijing group by real-tine PCR RT tests for LAM, S, Ural.
 Results. The isolates of the Beijing genotype (67.5%) were found to dominate both among newly diagnosed (64.4%) and previously treated patients (88.5%). MIRU-VNTR typing revealed 75 profiles, of which 94-32 (35.3%) and 100-32 (15.7%) were the most abundant and belonged to the Beijing genotype. Overall, 39.9% and 20.9% of isolates, respectively, were assigned to the Beijing Central Asian Russian and B0/W148 epidemic clusters, which differed significantly in MDR levels (50.8% and 85.3%, respectively; p = 0.005). The second most common were strains of the genetic family of the Euro-American lineage (L4) (31.9%): LAM (6.7%) Ural (7.4%) Haarlem (4.9%) and L4-unclassified (12.9%), MDR among of these minor genotypes was significantly lower than among Beijing genotype strains, and amounted to 11.5% (p 0.001). Strains from HIV-TB patients (56.4% of the total sample) carried an MDR profile more often (54.8%) compared to TB cases without HIV infection (35.2%) (p = 0.005), which may be due to higher proportion of Beijing genotype strains in the HIV-TB group (75.0% vs. 57.7%; p = 0.026). Complete comparability of the SNP analysis (in-house tests) to identify the main genotypes and epidemically significant Beijing subtypes was shown, which made it possible to characterize 75.5% of the sample by the express method.
 Conclusions. The molecular genetic screening carried out in the Kemerovo Region revealed the heterogeneity of the M. tuberculosis population, which was dominated by strains of the Beijing genotype, with the frequency of subtypes comparable with other territories of the Siberian Federal District.

Problems of monitoring malignant neoplasms of the central nervous system in the Siberian Federal District and ways to solve them

Incidence and recording of neuro-oncological tumors comprise an important problem in the world and In Russia including the Siberian federal district. To analyze the incidence of malignant tumors of the central nervous system (CNS) (C70-72) in the Siberian federal district and appropriate constituent territories. Analysis of standardized indicators was based on form No. 7 "Information on malignant neoplasms" for the period 2013-2022, population and male-to-female ratio in the Siberian federal district. The number of patients with CNS tumors increases in the Siberian federal district while relative rates of CNS cancer incidence are stable (men 5.2±0.2%, women 3.8±0.2%). The peak incidence has shifted from the age of 65-69 years to older category (75-79 years). Mean age of patients increased by 4.6 years (53.8±1.9 years in 2022) for men and 5.5 years (58.3±1.7 years in 2022) for women (p<0.001). We developed the algorithm for therapeutic and diagnostic care in patients with CNS tumors to solve permanent organizational problems in the Tomsk region. A specialized neuro-oncological registry based on territorial cancer registry was used. Development and implementation of neuro-oncological registry programs for all tumors of the central nervous system will be valuable to assess oncological epidemiological situation. Moreover, we can expect earlier diagnosis and timely specialized treatment of such patients.

Повышение эффективности экспорта масложировой продукции регионов Сибири

The purpose of the study is to increase the efficiency of export of oil and fat products from the regions of Siberia (Siberian Federal District (SFD)). The analysis of the current state of exports of fat and oil products from the regions of SFD is carried out. The article examines the dynamics and structure of exports of fat-and-oil products of the subjects of the Siberian Federal District, as well as the impact of state regulation of the fat-and-oil industry in the Russian Federation. The ranking of the regions of Siberia according to the degree of their influence on export revenue from the sale of fat and oil products is presented, the analysis of the geography of exports is given. Conclusions are drawn that, under certain conditions and for certain territories of the Russian Federation, state regulation measures for the oil and fat industry are not sufficiently effective to achieve their goals. The formed export-raw material model of economic development of the fat-and-oil subcomplex of the agro-industrial complex of Siberia is accompanied by a number of difficulties for existing exporters. The author focuses on the need to develop the processing of oilseeds in the regions of Siberia. In the Siberian Federal District, it is potentially effective to develop its own processing of oilseeds, changing the structure of agricultural exports, increasing the volume of sales of fat and oil products of medium and high technological conversion.

ПРОЯВЛЕНИЯ ЭПИДЕМИЧЕСКОГО ПРОЦЕССА ЭНТЕРОВИРУСНОЙ ИНФЕКЦИИ В СУБЪЕКТАХ ДАЛЬНЕВОСТОЧНОГО И СИБИРСКОГО ФЕДЕРАЛЬНЫХ ОКРУГОВ РОССИЙСКОЙ ФЕДЕРАЦИИ В 2023 Г. ПРОГНОЗ ЗАБОЛЕВАЕМОСТИ ЭНТЕРОВИРУСНОЙ ИНФЕКЦИЕЙ НА 2024 Г.

The annual increase in the incidence of enterovirus infection (EVI) in the population of the Far East and Eastern Siberia determines the need for constant epidemiological surveillance of EVI using molecular typing of enteroviruses.In 2023, a significant excess of the long-term average incidence rate of EVI was noted in 8 of the 16 analyzed territories of the Far Eastern and Siberian federal districts. The main clinical forms of EVI were herpangina and exanthema forms. Among the identified types of enteroviruses in 2023, coxsackievirus A6 predominated. Phylogenetic analysis revealed the circulation of a new variant of the eC2 genotype of the ECHO30. The calculation of prognostic indicators showed that an increase in EVI incidence in 2024 is expected in five analyzed territories. The manifestations of the EVI epidemic process in the territories of the Far Eastern and Siberian federal districts in 2023 were influenced by the active circulation of the coxsackievirus A6 and the emergence of a new ECHO30 genovariant. In the territories with high EVI incidence rates predicted for 2024, attention should be paid to the timely organization of epidemic control measures.

Роль приграничных муниципальных образований в обеспечении экономической безопасности региона (на материалах Сибирского федерального округа)

The article explores the role of border municipalities in contributing to the economic stability of Siberian regions. It analyses the current mechanisms of state control over border municipalities and summarises scientific approaches to understanding their situation. Additionally, it identifies indicators of economic stability at the municipal level. Based on data from five regions within the Siberian Federal District - the Omsk and Novosibirsk Regions, the Altai Territory, and the Republics of Altay and Tyva - the research conducted a comparative analysis of economic stability in their municipal and urban areas. The study identified vulnerable aspects of economic stability for local communities and assessed their influence on the development of the region as a whole. The article discusses the potential and tools for the impact of regulatory measures in the region on the development of local communities. It compares the economic efficiency indicators of neighboring municipalities and regions and reveals a significant difference in the indicators for border municipalities compared to the average regional values. The research findings can be used to develop a strategic policy for the district's development in the area of integrated development for border regions and constituent municipalities. Based on the research, the author concludes that a unified state policy is needed to ensure the economic stability of Siberia's border municipalities, and identifies some possible directions for implementing such a policy.

Концепция развития сельского хозяйства региона в условиях экологических ограничений (на материалах Республики Бурятия)

The article examines the peculiarities of the development of agriculture in regions with ecological restrictions. A methodology for calculating the level of environmental restrictions is proposed and the grouping of the regions of the Far Eastern and Siberian Federal Districts on this basis was carried out. A model of the functioning of the agro-socio-ecological-economic system of the region has been developed, establishing the interrelationships and interaction of innovative eco-oriented agriculture with the economic, social and environmental spheres. A concept for the development of agriculture in the Republic of Buryatia has been proposed. Scenarios for its development in inertial and optimistic variants have been considered.

Использование разноуровневых маркетинговых коммуникаций несетевыми продавцами отделочных материалов

The decrease in the effectiveness of conventional marketing communications and the need to optimize marketing budgets require modern non-network players in the finishing materials market to take a more balanced approach to the formation of an integrated set of communication tools. Within the framework of this study, four types of marketing information transmission channels were identified. A tiered approach was used for typing, based on determining the type and number of communication intermediaries between a non-network seller and a buyer of finishing materials. A list of opportunities and threats of using a communication channel is defined for each type, which allows operationalizing the process of developing marketing communications. In order to optimize the procedure of developing a marketing communications package, lists of relevant marketing communications tools were formed, ranked by the degree of influence on sales volumes. To conduct the research, methods of included observation, survey and analysis of marketing internal reporting documents were used. The objects of observation - non-network sellers of finishing materials in the Siberian Federal District. The respondents - specialists who make decisions on the integration of marketing communications.