You have accessJournal of UrologyInfections/Inflammation of the Genitourinary Tract: Prostate & Genitalia1 Apr 20111429 IS THERE EVIDENCE FOR ESWT THERAPY IN MEN WITH CHRONIC NONBACTERIAL PROSTATITIS/CHRONIC PELVIC SYNDROME? PRELIMINARY RESULTS OF A CONTROLLED STUDY Michael Mathers, Stephan Degener, Stephan Roth, and Theodor Klotz Michael MathersMichael Mathers Remscheid, Germany More articles by this author , Stephan DegenerStephan Degener Wuppertal, Germany More articles by this author , Stephan RothStephan Roth Wuppertal, Germany More articles by this author , and Theodor KlotzTheodor Klotz Weiden, Germany More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2011.02.1341AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Chronic prostatitis/pelvic pain syndrome (CPPS) is a common condition of unclear aetiology. Treatment modalities are often empirical with an uncertain outcome. Prostatic calcifications are often found, but a link to symptoms is controversial. There is a need for new treatment alternatives. Extra corporal shock wave lithotripsy (ESWT) might be a possible treatment option. METHODS A total of 24 men with CPPS refractory to multiple prior therapies were treated by extra corporal shock wave lithotripsy (ESWT). 14 men (verum group) were treated with ultrasound controlled ESWT of the prostate, 10 patients (sham group) with the ESWT focused to the filled bladder. The treatments were performed once weekly for at least three times in a prone position with a filled bladder on an classical shock wave lithotriptor (Modulith Storz CPX). 4 patients of the sham group changed to the verum group after three ESWT treatments. The first 5 patients were treated with an antibiotic for 5 days. The national Institute of health chronic prostatitis symptom index (NIH-CPSI), the International prostatic symptoms Score (IPSS), transrectal ultrasound and blood tests were performed at the beginning, after 4 weeks and after 3 months of therapy. Urine tests were performed before and after each ESWT treatment. Two patients (one patient in the verum, and one patient of the sham group) were lost to follow up. RESULTS Mean NiH-CPSI total score +/− SD decreased from 26.1 +/− 1,8 to 12.0 +/− 1.5 (p<0,0001) in the verum group after 3 months. Significant improvement was seen in each sub score domain. The sham group showed a lesser decrease of NIH-CPSI score: 26.4 +/− 1.7 to 18.3 +/− 1.7 (p<0,01). The IPSS score showed a similar improvement. 9 patients of the verum group however only 1 patient of the sham group reported on an immediate improvement of symptoms within 24 hours after the first ESWT. In three patients of the verum group and two patients of the sham group bacterial growth was found after ESWT. 2 patients of the verum group reported on a slight gross hematuria for several hours. After three to six months 7 patients of the verum group received a new series of ESWT treatment because of the reoccurrence of symptoms. CONCLUSIONS ESWT of the prostate in patients with CPPS seems to be a promising effective treatment. More prospective placebo controlled trials are required. © 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 185Issue 4SApril 2011Page: e572 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.MetricsAuthor Information Michael Mathers Remscheid, Germany More articles by this author Stephan Degener Wuppertal, Germany More articles by this author Stephan Roth Wuppertal, Germany More articles by this author Theodor Klotz Weiden, Germany More articles by this author Expand All Advertisement Advertisement PDF DownloadLoading ...