Professor Missotten was born in Hasselt, Belgium, on the 9th of October 1931. He passed away on Thursday, 27 June 2019. He is survived by his wife Marie-Helene Verhamme, his sons Pieter and Jan, his daughters Anne and Kathleen and his grandson Wolf. Professor Missotten graduated and received his medical degree from KU Leuven, Belgium, in 1955. He obtained his PhD degree in 1965, with a thesis entitled ‘The Ultrastructure of the Retina’. He was promoted to professor in 1975 and became the chair of the Department of Ophthalmology, College of Medicine, KU Leuven in 1978. Under his leadership, the Department of Ophthalmology progressed into an international centre for basic and translational research, establishing strong connections and productive international collaborations. As a research leader and mentor, Professor Missotten established a group of clinician–scientists at the KU Leuven with an outstanding contribution to translational science. His passion for research motivated many young Belgian and international ophthalmologists to pursue a research career. His scientific career was outstanding as he was the leading author or co-author of over 240 national and international publications. Professor Missotten had an encyclopedic knowledge of basic science, engineering, optics and clinical practice of Ophthalmology, which allowed him to lead in many areas of ophthalmic research. Many generations of ophthalmologists, to whom he served as a role model and mentor, will remember him as a very kind, open-minded, honest, dedicated and committed clinician–scientist. Professor Missotten has been my mentor and friend for the last 36 years, with whom I shared my research ideas and plans. Our friendship was deep, and his loss will be unforgettable. In addition to his contributions to clinical practice and research, Professor Missotten served as the editor of international research journals and was involved in several research societies. His efforts were instrumental to unite ophthalmic research groups in Europe and to establish European Association for Vision and Eye Research (EVER) in 1997. From 1997 to 2002, he served as the secretary-general of EVER. He was also very important for the European Society of Ophthalmology (SOE). He was Secretary General from 1984 to 1996 and then became the President and elder statesman of SOE from 1996 to 1998. His efforts transformed SOE from a club to a scientific society. He was honored by the Society with both the Helmholtz Medal and the Henkes Medal. Professor Missotten received many awards to his work, including the degree of ‘Doctor Honoris Causa’ from the University of Mansoura, Egypt, in 1996 for his efforts to supervise the research of many young Egyptian ophthalmologists to obtain PhD degrees. Professor Missotten, ‘you shall be remembered forever’.
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