Shape Asymmetry Research Articles

Ponderomotive potential effects on strong field two-photon double ionization in neon

Abstract In the context of the recently reported experiment on photoionization in neon atom, we theoretically study the photoionization of neon atom at a comparatively intense laser field. The calculated photoelectron spectrum for a Gaussian laser pulse show an asymmetric double peak line shape at a pulse duration of 14.2 fs and peak intensity of 1x1015 W/cm2. A systematic study clearly indicates that the ponderomotive potential of the photoelectron released during photoionization of neon is instrumental in causing the visible asymmetry. 
 Interestingly, for similar laser parameters asymmetry in the the photoelectron spectrum gets significantly reduced for a Sech2
shaped laser pulse. Time resolved photoelectron spectrum reveals that even for a Sech2 shaped laser pulse the two peak photoelectron spectrum is initially asymmetric and evolves into a symmetric line shape with increase in time. The results clearly indicate that irrespective of laser pulse shape asymmetry shows a non-linear decrease as a function of time. Our study also shows the possibility of controlling the asymmetry by varying the pulse duration. The calculations establishes a correlation between the effects of direct double ionization and ponderomotive potential on the asymmetry of the photoelectron spectrum at different pulse durations.

Intra and interspecies discrimination of three teleost species collected from the Komo Estuary in Gabon in relation to living depth levels using otolith shape analysis

ABSTRACT This study aimed to examine otolith shape and fluctuating asymmetry (FA) in pelagic Ethmalosa fimbriata, demersal Galeoides decadactylus, and benthic Cynoglossus monodi and assess their population status to inform on management procedures and verify whether or not otolith shape differs with living depth levels of these species in Lebe fishing site located along Komo Estuary, central-western Gabon. At intraspecies level, otolith shape analysis showed a bilateral asymmetry only in left and right otoliths between males and females of E. fimbriata and C. monodi. DFA separated between left and right and left-left and right-right otoliths shape of males and females within each species. At interspecies level, a significant bilateral asymmetry in left and right otolith shape was found among males and females of each species. DFA completely separated the left and right otoliths of both males and females of three species and confirmed the presence of three separate populations representing the three species, which should be managed separately. A significant FA on right and left otolith shapes was found among males and females at intra and interspecies levels. Accordingly, results indicated a close relationship between asymmetry of otolith shape and pelagic and benthic life characteristics of E. fimbriata and C. monodi.

Unraveling the complex interplay between abnormal hemorheology and shape asymmetry in flow through stenotic arteries

Background and Objective:Stenosis or narrowing of arteries due to the buildup of plaque is a common occurrence in atherosclerosis and coronary artery disease (CAD), limiting blood flow to the heart and posing substantial cardiovascular risk. While the role of geometric irregularities in arterial stenosis is well-documented, the complex interplay between the abnormal hemorheology and asymmetric shape in flow characteristics remains unexplored. Methods:This study investigates the influence of varying hematocrit (Hct) levels, often caused by conditions such as diabetes and anemia, on flow patterns in an idealized eccentric stenotic artery using computational fluid dynamics simulations. We consider three physiological levels of Hct, 25%, 45%, and 65%, representing anemia, healthy, and diabetic conditions, respectively. The numerical simulations are performed for different combinations of shape eccentricity and blood rheological parameters, and hemodynamic indicators such as wall shear stress (WSS), oscillatory shear index (OSI), are relative residence time (RRT) are calculated to assess the arterial health. Results:Our results reveal the significant influence of Hct level on stenosis progression. CAD patients with anemia are exposed to lower WSS and higher OSI, which may increase the propensity for plaque progression and rupture. However, for CAD patients with high Hct level—as is often the case in diabetes—the WSS at the minimal lumen area increases rapidly, which may also lead to plaque rupture and cause adverse events such as heart attacks. These disturbances promote endothelial dysfunction, inflammation, and thrombus formation, thereby intensifying cardiovascular risk. Conclusions:Our findings underscore the significance of incorporating hemorheological parameters, such as Hct, into computational models for accurate assessment of flow dynamics. We envision that insights gained from this study will inform the development of tailored treatment strategies and interventions in CAD patients with common comorbidities such as diabetes and anemia, thus mitigating the adverse effects of abnormal hemorheology and reducing the ever-growing burden of cardiovascular diseases.

Size-Controllable and Monodispersed Lipid Nanoparticle Production with High mRNA Delivery Efficiency Using 3D-Printed Ring Micromixers.

Lipid nanoparticles (LNPs) are gaining recognition as potentially effective carriers for delivery of therapeutic agents, including nucleic acids (DNA and RNA), for the prevention and treatment of various diseases. Much effort has been devoted to the implementation of microfluidic techniques for the production of monodisperse and stable LNPs and the improvement of encapsulation efficiency. Here, we developed three-dimensional (3D)-printed ring micromixers for the production of size-controllable and monodispersed LNPs with a high mRNA delivery efficiency. The effects of flow rate and ring shape asymmetry on the mixing performance were initially examined. Furthermore, the physicochemical properties (such as hydrodynamic diameter, polydispersity, and encapsulation efficiency) of the generated LNPs were quantified as a function of these physical parameters via biochemical analysis and cryo-electron microscopy imaging. With a high production rate of 68 mL/min, our 3D-printed ring micromixers can be used to manufacture LNPs with diameters less than 90 nm, low polydispersity (<0.2), and high mRNA encapsulation efficiency (>91%). Despite the simplicity of the ring-shaped mixer structure, we can produce mRNA-loaded LNPs with exceptional quality and high throughput, outperforming costly commercial micromixers.

Diffusion dynamics of an overdamped active ellipsoidal Brownian particle in two dimensions

Shape asymmetry is the most abundant in nature and has attracted considerable interest in recent research. The phenomenon is widely recognized: a free ellipsoidal Brownian particle displays anisotropic diffusion during short time intervals, which subsequently transitions to an isotropic diffusion pattern over longer timescales. We have further expanded this concept to incorporate active ellipsoidal particles characterized by an initial self-propelled velocity. This paper provides analytical and simulation results of diffusion dynamics of an active ellipsoidal particle. The active ellipsoidal particle manifests three distinct regimes in its diffusion dynamics over time. In the transient regime, it displays diffusive behavior followed by a super-diffusive phase, and in the longer time duration, it transitions to purely diffusive dynamics. We investigated the diffusion dynamics of a free particle as well as a particle in a harmonic trap, and a particle subject to a constant field force. Moreover, we have studied the rotational diffusion dynamics and torque production resulting from an external constant force field. Furthermore, our investigation extends to the examination of the scaled average velocity of an ellipsoidal active particle, considering both a constant force field and a one-dimensional ratchet.

Shape variations of pelvis in different classes of dogs using geometric morphometry.

The ossa coxae are the bones that connect the hindlimbs to the axial skeleton. The right and left os coxae join at the median plane to form the pelvis. In this study, variations in pelvis shape and the asymmetric structure of the pelvis were investigated across different classes of dogs. To achieve this, computed tomography images of the pelvis were obtained from 35 dogs, and 3D modelling of the pelvis was created. Subsequently, 45 landmarks were identified on these models. As a result of the Principal Component Analysis, the shape variation was observed in the pelvic canal and crista iliaca. Directional asymmetry between Principal Component 1 and Principal Component 2 accounted for 33.84% of the total variation, while fluctuating asymmetry contributed 23.66%. Canonical variate analysis revealed that canonical variate (CV) 1 explained 56.56% of the total variation between groups, with CV 2 explained 28.98%. Male dogs exhibited greater pelvic variation than females. Procrustes ANOVA indicated that the greatest proportion of shape variation corresponds to the effect of differences among individuals. While directional asymmetry was statistically significant, fluctuating asymmetry was not. Male dogs displayed more pronounced pelvic shape asymmetry, typically towards the right. Gundogs had a narrower pelvic canal and a wide crista iliaca, whereas terriers had a wider pelvic canal and smaller crista iliaca in shape. Geometric morphometry enables statistical analysis and the derivation of average shapes from samples, making it a vital tool in veterinary anatomy. This study provides insights into pelvic geometric morphometry across different classes of dogs.

Combined axial load-biaxial bending interaction method for L-shaped CFSP shear walls

This paper reports the development of axial load and biaxial bending interaction method for L-shaped concrete-filled steel plate (CFSP) composite shear walls based on fiber section analysis model using the uniaxial constitutive relationship of materials. Owing to the complex interaction between the two perpendicular wall limbs (web and flange) of an L-shaped shear wall, the contour shape of the My-Mz curve is asymmetric. Linear transformation was employed to reduce the asymmetry of the contour shape, eliminate the influence of dimension, and perform parametric analysis. The analysis results indicate that when 0° ≤ θ(neutral axis angle) ≤ 90°, the influence of width-to-thickness ratio (hw1/bw) and shape coefficient (γ) on the coefficient that controls the contour shape (α) was negligible. The effect of shape coefficient (γ), steel content ratio (ρ), compressive strength of unconfined concrete (fc0), and yield strength of steel plate (fyp) on α is not significant for −180° ≤ θ ≤ −90°. Further, simplified equations were suggested to determine α. The axial load-moment interaction curve expressions for distinctive loading directions were determined by establishing the calculation method for the curve's characteristic points (axial load capacity, bending capacity, boundary points). Subsequently, the characteristic points were combined with the contour shape of the axial load-moment interaction curve derived by fitting the finite element simulation data to generate the axial load-moment interaction curve equations. A design approach was finally formulated based on the equations for the biaxial moment capacity curve and the axial load-moment interaction curves of the characteristic loading directions.

Asymmetrical Lateral Crus Steal in Geometric Tip Reshaping.

A key component of a well-performed rhinoplasty is to obtain the proper, aesthetic shape of the nasal tip. Various surgical techniques have been developed to achieve this effect. In this work, the author wanted to focus not only on the satisfactory shape of the nose, but above all on its main role-functionality. In this article, the asymmetrical lateral crus steal (ALCS) technique is proposed, which in its assumption will enable narrowing, better defining and rotating of the nasal tip, and at the same time enhancing nasal patency. We present a retrospective analysis within the group of 267 patients who underwent primary open-approach rhinoplasty that included the ALCS technique. The mean follow-up time was 12 months. A total of 232 patients achieved very good postoperative results without observation of any serious complications related to breathing difficulties or asymmetry of the nasal tip shape. ALCS is a relatively simple surgical technique to perform. The use of the ALCS suture creates the possibility of proper profiling of the nasal tip while improving the respiratory functions of the nose.

AI-generated faces show lower morphological diversity than real faces do

Some recent studies suggest that artificial intelligence can create realistic human faces subjectively unrecognizable from faces of real people. We have compared static facial photographs of 197 real men with a sample of 200 male faces generated by artificial intelligence to test whether they converge in basic morphological characteristic such as shape variation and bilateral asymmetry. Both datasets depicted standardized faces of European men with a neutral expression. Then we used geometric morphometrics to investigate their facial morphology and calculate the measures of shape variation and asymmetry. We found that the natural faces of real individuals were more variable in their facial shape than the artificially generated faces were. Moreover, the artificially synthesized faces showed lower levels of facial asymmetry than the control group. Despite the rapid development of generative adversarial networks, natural faces are thus still statistically distinguishable from the artificial ones by objective measurements. We recommend the researchers in face perception, that aim to use artificially generated faces as ecologically valid stimuli, to check whether their stimuli morphological variance is comparable with that of natural faces in a target population.

Hot subdwarfs in close binaries observed from space

Detailed studies of hot subdwarf B (sdB) stars with red dwarf (dM) or brown dwarf (BD) companions can shed light on the effects of binarity on late stellar evolution. Such systems exhibit a strong, quasi-sinusoidal reflection effect due to irradiation of the cool companion, and some even show primary and secondary eclipses. For this work, we computed Fourier transforms of TESS light curves of sdB+dM/BD binaries and investigate correlations between the relative amplitudes and phases of their harmonics and system parameters. We show that the reflection effect shape strongly depends on the orbital inclination, with nearly face-on systems having much more sinusoidal shapes than nearly edge-on systems. This information is encoded by the relative strength of the first harmonic in the Fourier transform. By comparing observations of solved systems to synthetic light curves generated by lcurve, we find that the inclination of non-eclipsing systems with high signal-to-noise light curves can be determined to within ≈10° simply by measuring their orbital periods and first harmonic strengths. We also discovered a slight asymmetry in the reflection effect shape of sdB+dM/BD binaries using the relative phase of the first harmonic. From our analysis of synthetic light curves, we conclude the asymmetry results from relativistic beaming of both stellar components. This marks the first time Doppler beaming has been detected in sdB+dM/BD systems. Although advanced modeling is necessary to quantify the effects of secondary parameters, such as limb darkening, the temperature ratio, and the radius ratio on the reflection effect shape, our pilot study demonstrates that it might be possible to extract both the inclination angle and cool companion velocity from the light curves of non-eclipsing systems.

Dimorphos’s Orbit Period Change and Attitude Perturbation due to Its Reshaping after the DART Impact

On 2022 September 26 (UTC), NASA's Double Asteroid Redirection Test (DART) mission achieved a successful impact on Dimorphos, the secondary component of the near-Earth binary asteroid system (65803) Didymos. Subsequent ground-based observations suggest a significant reshaping of Dimorphos, with its equatorial axis ratio changing from 1.06 to ∼1.3. Here we report the effects of this reshaping event on Dimorphos's orbit and attitude. Given the reported reshaping magnitude, our mutual dynamics simulations show that approximately 125 s of the observed 33 minute orbit period change after the DART impact may have resulted from reshaping. This value, however, is sensitive to the precise values of Dimorphos's post-impact axis ratios and may vary by up to 2 times that amount, reaching approximately 250 s within the current uncertainty range. While the rotational state of the body is stable at the currently estimated axis ratios, even minor changes in these ratios or the introduction of shape asymmetry can render its attitude unstable. The perturbation to Dimorphos’s orbital and rotational state delivered by the impact directly, combined with any reshaping, leads to a strong possibility for a tumbling rotation state. To accurately determine the momentum enhancement factor (β) through measurements by the European Space Agency’s Hera spacecraft and to evaluate the effectiveness of the kinetic deflection technique for future planetary defense initiatives, the effects of reshaping should not be overlooked.

QUANTIFYING HIPPOCAMPAL SHAPE ASYMMETRY IN ALZHEIMER'S DISEASE USING OPTIMAL SHAPE CORRESPONDENCES.

Hippocampal atrophy in Alzheimer's disease (AD) is asymmetric and spatially inhomogeneous. While extensive work has been done on volume and shape analysis of atrophy of the hippocampus in AD, less attention has been given to hippocampal asymmetry specifically. Previous studies of hippocampal asymmetry are limited to global volume or shape measures, which don't localize shape asymmetry at the point level. In this paper, we propose to quantify localized shape asymmetry by optimizing point correspondences between left and right hippocampi within a subject, while simultaneously favoring a compact statistical shape model of the entire sample. To account for related variables that have an impact on AD and healthy subject differences, we build linear models with other confounding factors. Our results on the OASIS3 dataset demonstrate that compared to volumetric information, shape asymmetry reveals fine-grained, localized differences that inform us about the hippocampal regions of most significant shape asymmetry in AD patients.

Nanoscopic Imaging of Self-Propelled Ultrasmall Catalytic Nanomotors.

Ultrasmall nanomotors (<100 nm) are highly desirable nanomachines for their size-specific advantages over their larger counterparts in applications spanning nanomedicine, directed assembly, active sensing, and environmental remediation. While there are extensive studies on motors larger than 100 nm, the design and understanding of ultrasmall nanomotors have been scant due to the lack of high-resolution imaging of their propelled motions with orientation and shape details resolved. Here, we report the imaging of the propelled motions of catalytically powered ultrasmall nanomotors─hundreds of them─at the nanometer resolution using liquid-phase transmission electron microscopy. These nanomotors are Pt nanoparticles of asymmetric shapes ("tadpoles" and "boomerangs"), which are colloidally synthesized and observed to be fueled by the catalyzed decomposition of NaBH4 in solution. Statistical analysis of the orientation and position trajectories of fueled and unfueled motors, coupled with finite element simulation, reveals that the shape asymmetry alone is sufficient to induce local chemical concentration gradient and self-diffusiophoresis to act against random Brownian motion. Our work elucidates the colloidal design and fundamental forces involved in the motions of ultrasmall nanomotors, which hold promise as active nanomachines to perform tasks in confined environments such as drug delivery and chemical sensing.

Urbanization effects on growth and otolith asymmetry in Chrysichthys nigrodigitatus and Oreochromis niloticus within tropical coastal lagoon watersheds

In this study, we investigated the growth dynamics and otolith shape asymmetry of two fish species, Chrysichthys nigrodigitatus (CN) and Oreochromis niloticus (ON), within urbanized watersheds of the southern lagoon system, Nigeria. Using the von Bertalanffy growth model (VBGM), in addition to sediment metal concentration indices such as the average shale content, index of geoaccumulation (Igeo), contamination factor (CF), pollution load index (PLI), and potential ecological risk (PER) index, contamination levels were classified, and ecological risks were assessed. Notably, a lower growth potential (t0) was observed in CN at Ikorodu than at Epe, with similar trends for ON in the Epe during the dry season. Otolith asymmetry patterns, particularly in the CN at Ikorodu and ON in the Epe during the dry season, exhibited distinct ecological variations, indicating heightened stress levels at Ikorodu. Sediment analyses revealed moderate to strong contamination (Cd, Pb, Ni, and Cr) in both Lagos Lagoon (Ikorodu) and Epe Lagoon, with Ikorodu exhibiting notably high to moderate contamination levels according to the CF index. Elevated PLI values for Cd and Pb in Ikorodu, in addition to greater PER, indicated increased risk, with Cd posing a high risk (61.42%) and Pb posing a moderate risk (49.50%). Additionally, the reduced asymptotic length in the Epe during the dry season suggests that Chrysichthys nigrodigitatus is adaptable to seasonal variations, while divergent growth patterns in both areas indicate the existence of trade-off mechanisms in response to changing conditions. Habitat-specific otolith asymmetry and metal contamination underscore species adaptability, with wider stressor variability in Lagos than in Epe. Furthermore, multidimensional scaling analysis highlights the intricate relationship between otolith shape variables and environmental factors, emphasizing the need for tailored conservation efforts in urbanized watersheds.

Triaxiality dynamics in quadrupole deformed heavy even–even nuclei

In the framework of free triaxiality model, branching ratio of reduced E2-transitions probabilities is studied for the full region changes of the triaxiality parameter. The variables of quadrupole deformations [Formula: see text] and [Formula: see text] are dynamic. The Davidson potential for [Formula: see text] and [Formula: see text] variables was used. In the free triaxiality model, the energy levels were obtained by taking into account the high-order terms of the rotational energy operator series, which lead energy levels of ground-state-band, [Formula: see text]- and [Formula: see text]-bands to improve considerably the agreement of the results with experimental data. The quadrupole moment of the nucleus expressed in terms of two internal quadrupole moments: [Formula: see text] is quadrupole moment about the symmetry axis, [Formula: see text] is the measure of the shape asymmetry about the symmetry axis. The intra/inter-band reduced E2-transition probabilities’ ground-state-band, [Formula: see text]- and [Formula: see text]-bands are presented and are expressed in terms of four parameters: [Formula: see text], [Formula: see text], [Formula: see text] and [Formula: see text]. The influence of [Formula: see text]-oscillations to the reduced probabilities of E2-transitions is taken into account numerically. The sensitivity of the intra-/inter-band reduced E2-transition probabilities to the triaxiality parameter was analyzed.

Дифференциальная диагностика невусов и меланом хориоидеи по данным ОКТ

The article presents the study results of 64 patients with suspicious (progressive) nevi (n = 42) and initial choroid melanomas (n = 22, of which n = 3 had anamnesis of choroid nevus). Ultrasound examination, digital photoregistration of the fundus and OCT were done for all patients. According to the OCT data it was possible to identify diagnostic criteria that help distinguish of suspicious nevi including those with a high risk of malignant transformation from initial choroid melanomas. First of all these are the preservation of the Bruch membrane and the presence of druses. While malignant transformation of suspicious nevi was characterized by shape asymmetry of the enlarged “choroidal complex”, dilation of large choroidal vessels around the nevus, the presence of RPE detachment and the presence of hyperreflective intraretinal inclusions. Criteria of initial choroid melanomas were violation of the integrity of the Bruch membrane, rounded cavities in the inner layers of the choroid, deposits at the level of RPE, edema and/or rupture of the photoreceptor layer. Keywords: suspicious choroid nevus, choroid melanoma, OCT

Toward One‐Way Smoke: Synthesis of Copper‐Based Microclubs with Asymmetric Scattering and Absorption

AbstractThe ultimate goal of this work is to create an engineered aerosol that acts as one‐way smoke, i.e. it creates an asymmetric vision environment in which the ability to image objects depends on the viewing direction. To this end, a rapid, one‐pot synthesis of copper‐based microclubs is developed that consists of a Cu2O octahedron attached to a Cu2O@Cu shaft. Millions of synthesized particles are analyzed in minutes with a FlowCam to provide a robust statistical analysis of their geometry, and rapidly elucidate the roles of the reaction constituents on the particle shape and yield. The combination of asymmetry in both shape and composition introduces a 30% difference in scattering of light propagating parallel to the microclub axis from opposing directions. This work represents a first step toward the creation of an asymmetric imaging environment with an aerosol consisting of acoustically aligned microclubs.

A smart granular intruder

It has been recently reported that irregular objects sink irregularly when released in a granular medium: a subtle lack of symmetry in the density or shape of a macroscopic object may produce a large tilting and deviation from the vertical path when released from the free surface of a granular bed. This can be inconvenient—even catastrophic—in scenarios ranging from buildings to space rovers. Here, we take advantage of the high sensitivity of granular intruders to shape asymmetry: we introduce a granular intruder equipped with an inflatable bladder that protrudes from the intruder's surface as an autonomous response to an unwanted tilting. So, the intruder's symmetry is only slightly manipulated, resulting in the rectification of the undesired tilting. Our smart intruder is even able to rectify its settling path when perturbed by an external element, like a vertical wall. The general concept introduced here can be potentially expanded to real-life scenarios, such as “smart foundations” to mitigate the inclination of constructions on a partially fluidized soil.

Minimal numerical ingredients describe chemical microswimmers' 3-D motion.

The underlying mechanisms and physics of catalytic Janus microswimmers is highly complex, requiring details of the associated phoretic fields and the physiochemical properties of catalyst, particle, boundaries, and the fuel used. Therefore, developing a minimal (and more general) model capable of capturing the overall dynamics of these autonomous particles is highly desirable. In the presented work, we demonstrate that a coarse-grained dissipative particle-hydrodynamics model is capable of describing the behaviour of various chemical microswimmer systems. Specifically, we show how a competing balance between hydrodynamic interactions experienced by a squirmer in the presence of a substrate, gravity, and mass and shape asymmetries can reproduce a range of dynamics seen in different experimental systems. We hope that our general model will inspire further synthetic work where various modes of swimmer motion can be encoded via shape and mass during fabrication, helping to realise the still outstanding goal of microswimmers capable of complex 3-D behaviour.

Shape Asymmetries and the Relation between Lopsidedness and Radial Alignment in Simulated Galaxies

Galaxies are observed to be lopsided, meaning that they are more massive and more extended along one side than the opposite side. In this work, we provide a statistical analysis of the lopsided morphology of 1780 isolated satellite galaxies generated by the TNG50-1 simulation, incorporating the effect of tidal fields from halo centers. The isolated satellites are galaxies without nearby substructures whose mass is over 1% of the satellites within their virial radii. We study the radial alignment (RA) between the major axes of satellites and the radial direction of their halo centers in radial ranges of 0–2, 2–5, and 5–10 R h , with R h being the stellar half-mass radius. According to our results, the RA is virtually undetectable in inner and intermediate regions, yet it is significantly evident in outer regions. We also calculate the far-to-near-side semiaxial ratios of the major axes, denoted by a −/a +, which measure the semiaxial ratios of the major axes in the hemispheres between those facing away from (far side) and facing toward (nearside) halo centers. In all the radial bins of the satellites, the numbers of satellites with longer semiaxes on the far side are found to be almost equal to those with longer semiaxes on the near side. Therefore, the tidal fields from halo centers play a minor role in the generation of lopsided satellites. The long semimajor-axes radial alignment (LRA), i.e., an alignment between the long semimajor axes of satellite galaxies and the radial directions to their halo centers, is further studied. No clear evidence of LRA is found in our sample within the framework of ΛCDM Newtonian dynamics. Finally, we briefly discuss the possible origins of the asymmetry of galaxies in TNG50-1.