Qian, X., 2020. Geological structure and oil and gas exploration of the Eastern Mediterranean. In: Hu, C. and Cai, M. (eds.), Geo-informatics and Oceanography. Journal of Coastal Research, Special Issue No. 105, pp. 119–123. Coconut Creek (Florida), ISSN 0749-0208.The continental shelf of the Eastern Mediterranean contains abundant hydrocarbon resources. With the continuous development of exploration technology, many large and superlarge oil and gas fields have been discovered in the Levant Basin and the Nile Delta Basin. The hydrocarbon reservoirs in the Levant Basin are mainly distributed in the Oligocene–Lower Miocene Tamar sandstone and Miocene shale caprock. The shallow-water area of the Nile Delta Basin has a high degree of exploration and complete production facilities, making it the best area for rolling exploration; the mid- to deep-water Oligocene section will be the main potential area for the future discovery of large- and medium-sized natural gas fields; the ultra-deep-water area has the exploration potential of large-scale Miocene and Pliocene biogas reservoirs. The discovery of offshore gas fields may quickly change the situation of long-term energy shortages and is potentially of great significance to changing the energy supply pattern in the region.