This article reviews the management of open fractures, which occur when there is a break in the skin exposing the underlying bone and soft tissues, leading to signicant morbidity and mortality. The article focuses on the initial evaluation, classication, and treatment of these fractures. The Gustilo-Anderson classication system, which is based on the degree of soft tissue injury, is the most widely used classication system for open fractures. However, the Tscherne classication system, which focuses on the severity of soft tissue injury and the degree of fracture displacement, has been shown to be a more reliable predictor of infection and nonunion in some studies. The article also covers the AO/OTA classication system, a newer classication system that integrates important aspects of the Gustilo-Anderson classication system to provide more comprehensive guidance for the treatment of open fractures. Treatment of open fractures is complex and requires a multidisciplinary approach guided by the severity of the injury. Early antibiotics, early surgical debridement, and wound irrigation have been shown to reduce the risk of infection and improve outcomes. Patients with open fractures were more likely to have associated injuries, longer hospital stays, and higher hospital costs compared to patients with closed fractures
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