Rational use of nutritional supplements is extremely important for better survival of the patient, especially in children where poor nutritional status will cause many co-morbid conditions with an increased risk of death. About 35% of under-five space deaths in the world are associated with malnutrition. Nutrition also place a major role in maternal health poor maternal nutritional status has been related to adverse birth outcomes [1]. The aim of the study was to assess the nutritional supplements prescribed in pregnant women and pediatric patients. A six month hospital based prospective observational study was carried out in the department of pediatric and gynecology at BTGH, Gulbarga. The aim of the study was to assess the nutritional supplements prescribed in pregnant women and pediatric patients at the respective departments. The data was collected in a specially designed data collection form, from the case sheet of inpatient of pediatric department and outpatient of gynecology department enrolled into the study [2]. The study result shows that out of 75 patients in pediatric department, 41 (54.66%) were females and 34(45.33%) were males, malnutrition is more prevalent in toddlers (1-5 years) i.e. 48 patients (64%) when compared to neonates (up to 1 month) 02(2.66%), infants (1month-1year) 20(26.66%), children (5-14years), 5(6.66%).the educational status of their parents 27(36.00%) were grade 0 followed by 19(25.33%) were belonged to grade 1,6(8%) belonged to grade 2,11(14.66%) belonged to grade 3 and 10(13,33%) belonged to grade 4. Out of 75 patients grade 2 PEM 33(44%) is more when compared to grade 1 PEM 7(9.33%), grade 3 PEM 19(25.33%) and grade 4 PEM 16(21.33%). 57 patients were improved 14 patient were discharged under request, 4 patient were referred and 00 deaths are reported [3]. The majority of supplements were administered orally (75%) followed by parenteral route 25% various types of nutrients are prescribed in pediatrics majority including multi vitamin, elemental iron +folic acid, vit A, vit C, zinc acetate, calcium carbonate+vitD3, electrolytes. the majority of prescription were with brand name (73.33%) followed by generic name (26.66%) among the associated co-morbidity conditions with malnutrition bronchopneumonia (13.33%) followed by severe anemia (10.66%), nutritional anemia (12%), acute gastroenteritis (9.33%),pulmonary TB (6.66%) and others [4]. [Table 1-5] Out of 100 pregnant women 50(25%) are of second trimester, 25(25%) are of first trimester, 25(25%) are of third trimester the majority of prescription were with brand name (72%) followed by generic name (28%). Majority of the supplements were administered orally (90%) when compared to parenteral administration (10%). The nutrients prescribed for pregnant women include T.doxinate plus for 47 patients, T.livogen Z (68 patients), T.mecalvit (65 patients), T.orofer XT (19 patients), cap. Becosule (23 patients), protein powder (25 patients), T.folvite (7 patients) [5]. [Table 6-9] The economic and literacy status of the households are the main factors causing nutritional imbalances in children. The number of cases reported concluded the shortage of nutrients to this region and unawareness in pregnant women [6].