In this paper we obtain different sufficient conditions for a non-autonomous discrete system to be multi-sensitivite. We study properties of a multi-sensitive non-autonomous system in detail. It is proved that on a compact metric space every finitely generated non-autonomous system which is topologically transitive having dense set of periodic points is thickly syndetically sensitive. We introduce and study the notion of totally sensitive non-autonomous systems. We also provide counter examples to support our results.