A commonly observed failure mode in laboratory tests involving surface bonded fiber-reinforced polymer (FRP) laminates or near-surface-mounted (NSM) bars is premature delamination, that is, the separation of the FRP from the substrate well before the FRP reaches its ultimate strain capacity. To delay the onset of delamination and to ensure that the NSM FRP reinforcement continues to contribute to member strength after partial delamination, a new self-anchored carbon fiber-reinforced polymer (CFRP) bar was developed and tested for this investigation. This bar is made with a series of monolithic spikes that can be anchored deep inside the concrete. In addition to cutting grooves into the concrete cover for the placement of the primary reinforcing bar, holes are drilled deep into the concrete to insert the spikes. To test the performance of this bar, six large, simply supported, reinforced, concrete beams were retrofitted with NSM bars and tested in four-point bending. Two beams were strengthened with NSM bars without anchors or spikes but were otherwise similar to the self-anchored bar and served as control specimens (Series B1). Two beams were strengthened in flexure with the new self-anchored NSM bars (Series B2), and the remaining two beams (Series B3) were strengthened in flexure and shear by using the self-anchored NSM bars as partial shear reinforcement. The effect of the proposed strengthening system on the beams’ strength, failure mode, deformability, and ductility are discussed on the basis of the experimental results. The anchors delayed delamination and enabled the NSM bar to experience at least a 77% higher strain at failure than the companion bar without anchors. The anchors also increased beam displacement ductility and energy ductility at a 20% strength degradation by at least 34% and 42%, respectively.