The present study investigated the influence of lexical links and conceptual mediation in number word translation. In four experiments, a semantic blocking paradigm was used with numerical stimuli and stimuli from other non-number categories. The performance of Spanish L1–English L2 bilinguals was examined in backward and forward translation (Experiment 1 and 3), in naming Arabic digits and pictures (Experiment 2A) and in reading L1 and L2 words (Experiment 2B). The blocked context produced a facilitatory effect for numerical stimuli in the lower range. This result contrasts with the interference effect observed for stimuli from non-number categories in translation and naming tasks. These results are interpreted to mean that the translation of number words, particularly those in the lower range of the numeric sequence, takes place with a large influence of the lexical connections. It supports the suggestions that the influence of processing routes depends on the type of items.