Self-rating Anxiety Scale Research Articles

The impact of sleep interventions combined with enhanced nutritional support on sleep quality, nutritional status, pain management, psychological well-being, and quality of life in postoperative colon cancer patients

ObjectiveTo investigate the synergistic effects of combined sleep interventions and enhanced nutritional support on postoperative recovery in colon cancer patients, with a focus on sleep quality, nutritional status, pain management, psychological well-being, and quality of life.MethodsThis randomized controlled trial included 290 postoperative colon cancer patients admitted to the First Affiliated Hospital of Soochow University between May 2021 and May 2023. Participants were randomized into two groups: the intervention group, which received standard care supplemented with sleep and nutritional interventions, and the control group, which received standard care alone. Outcomes were assessed pre- and post-intervention, including the Pittsburgh Sleep Quality Index (PSQI), nutritional markers (serum albumin, prealbumin, body weight, etc.), Visual Analog Scale (VAS) for pain, Self-Rating Anxiety and Depression Scales (SAS, SDS), and EORTC QLQ-C30 quality of life scores.ResultsThe intervention group demonstrated significantly greater improvements across all assessed domains compared to the control group ( P < 0.005 after Bonferroni correction). Sleep quality (PSQI: 7.81 vs. 10.43, d = 0.81) and nutritional markers (e.g., prealbumin: 230.19 mg/L vs. 188.01 mg/L, d = 1.21 ) improved markedly. Similarly, reductions in pain (VAS: 2.65 vs. 5.19,d = 1.09 ), anxiety (SAS: 42.03 vs. 49.45, d = 0.88), and depression (SDS: 38.17 vs. 49.77,d = 1.02 ) were observed. Quality of life scores significantly increased in the intervention group compared to the control group (EORTC QLQ-C30: 99.29 vs. 88.41, d = 0.92).ConclusionThe combined intervention of sleep enhancement and nutritional support significantly accelerated postoperative recovery in colon cancer patients, demonstrating synergistic effects that improved physical, psychological, and quality-of-life outcomes. These findings underscore the value of integrating multifaceted interventions into standard postoperative care to optimize recovery trajectories and overall well-being.

Neuroanatomical Insights: Convergence and Divergence of Tinnitus with Normal or Mild Hearing Loss

Objectives: To explore the neuroanatomical abnormalities in idiopathic tinnitus patients by voxel-based morphometry (VBM) and surface-based morphometry (SBM) techniques. To elucidate the central plasticity in tinnitus patients with normal or mild hearing loss from the neuroanatomical insights. Methods: A total of 74 patients with idiopathic tinnitus (43 with normal hearing and 31 with mild hearing loss) and 98 healthy subjects were enrolled. VBM and SBM were employed to analyze neuroimaging data and identify neuroanatomical differences. Results: Our analysis revealed a reduction in gray matter volume and a distinctive pattern of changes in cortical surface features in patients with idiopathic tinnitus, especially in brain regions closely related to the limbic system, such as the bilateral parahippocampal gyrus, bilateral entorhinal cortex, and insula. Tinnitus patients with mild hearing loss have more extensive gray matter volume reduction, and more complex changes in cortical surface features compared to tinnitus patients with normal hearing. In addition, we also found a significant correlation between the Self-Rating Anxiety Scale (SAS), the Self-Rating Depression Scale (SDS), and Montreal Cognitive Assessment (MoCA) scores of patients with idiopathic tinnitus and cortical characteristic parameters in the above brain regions. Conclusions: There are extensive neuroanatomical alterations in tinnitus patients. Mild hearing loss may aggravate the reduction of gray matter volume and change the surface characteristics of the cortex. Anxiety, depression, and cognitive impairment in patients with idiopathic tinnitus may be related to neuroanatomical alterations in specific brain regions.

An interventional study on the application of heart-collateral-based enlightenment words intervention in anxiety and depression of patients after percutaneous coronary intervention

ObjectiveTo study the effect of heart-collateral-based enlightenment words intervention on anxiety and depression in patients following percutaneous coronary intervention (PCI).MethodsIn this class experimental study, one hundred patients who were hospitalized after PCI from May 2020 to October 2021, were included in this interventional study. They were divided into the test group (n = 50) and the control group (n = 50) based on the random number table. The heart-collateral-based enlightenment words intervention was used in the test group versus routine nursing in the control group. Data was collected using a self-rating anxiety scale (SAS), self-rating depression scale (SDS), and an independently developed satisfaction questionnaire. Psychological indicators and satisfaction were compared between the two groups before and after the intervention.ResultsAfter 3 months of intervention, the test group scored significantly lower in SDS and SAS than the control group (SDS score: [55.06 ± 8.63] vs. [62.90 ± 9.52]; SAS score: [46.83 ± 10.24] vs. [56.02 ± 8.92]) (P < 0.05 for both SDS and SAS difference). The satisfaction rate of the test group vs. control group was 96% vs. 82% after the intervention, with a statistically significant difference (P < 0.05).ConclusionHeart-collateral-based enlightenment words intervention can effectively alleviate anxiety and depression in patients after PCI and increase their satisfaction with nursing services. To develop the theory and guide clinical practice, future research in different treatment area with larger sample size should be conducted.

Sleep quality during pregnancy following assisted reproductive technology and natural conceiving: a prospective birth cohort study

PurposeTo investigate the association of sleep quality during pregnancy on in vitro fertilization/intra-cytoplasmic sperm injection (IVF/ICSI) and natural conceiving (NC), as well as anxiety, depression, and perceived stress.MethodsThis prospective cohort study includes 500 infertile pregnant women undergoing IVF/ICSI and 678 NC women in a Sichuan birth cohort. Data on sleep, anxiety, depression, and stress was collected in the first trimester (T1), second trimester (T2), and third trimester (T3) using integrated questionnaires. Sleep quality is quantified by the Pittsburgh Sleep Quality Index (PSQI) with a cut-point of 5 indicating poor sleep. The Self-rating Anxiety Scale (SAS), the Center for Epidemiologic Study of Depression scale (CES-D), and the Perceived Stress scale (PSS) were used for assessing anxiety, depression, and perceived stress symptoms. Additionally, the matched husbands are surveyed. Multivariable logistic regression models with adjustments for influencing factors were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for the associations of sleep quality.ResultsIn the IVF/ICSI group, 61.1%, 55.5%, and 66.5% of participants in T1, T2, and T3 reported poorer sleep quality compared to the NC group, which had 43.2%, 37.4%, and 46.4% throughout the same trimesters. Additionally, the IVF/ICSI group exhibited higher levels of negative psychological factors as measured by the CES-D and PSS during T1 and T2, showing statistical significance in T1 (P = 0.008, P &amp;lt; 0.001) and T2 (P = 0.038, P &amp;lt; 0.001), except at T3 (P = 0.107, P = 0.253). In addition to psychological factors and IVF/ICSI treatment, poor sleep quality was also associated with advanced age. However, there was no significant difference in sleep quality between the husbands of the IVF/ICSI and NC groups.ConclusionThe study reveals that women receiving IVF/ICSI treatment are at a higher risk of experiencing sleep disturbances throughout their pregnancy compared with women with natural conception. While partners typically do not report major sleep problems, they do exhibit increased anxiety levels. These findings underscore the necessity for screening and addressing sleep issues in women pregnant through assisted IVF/ICSI treatment, to promote their well-being during this critical period.

The efficacy and safety of patient-controlled intravenous analgesia with esketamine after total hip arthroplasty: a randomized controlled trial

PurposeTo evaluate the efficacy and safety of esketamine-based patient-controlled intravenous analgesia following total hip arthroplasty.MethodsA total of 135 total hip arthroplasty patients were randomly assigned to one of the three treatment groups: esketamine, sufentanil or continuous fascia iliaca compartment block (FICB) group. The primary endpoint was the postoperative visual analogue scale (VAS) pain scores at rest and on movement. Secondary endpoints included preoperative 1-day and postoperative 7-day Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) scores, the satisfaction of patients and surgeons, postoperative 1-month and 3-month Harris function scores, the incidence of adverse reactions.ResultsAt 48 h post-surgery, the VAS pain scores in the esketamine and FICB groups at rest and on movement were significantly lower than those in the sufentanil group (P < 0.05). The satisfaction of patients in the esketamine group was higher than that in the sufentanil and FICB groups (P = 0.014). The satisfaction of surgeons in the esketamine and FICB groups was higher than that in the sufentanil group (P = 0.002). At postoperative day 7, the SAS scores and SDS scores in the esketamine group were significantly lower than those in the sufentanil and FICB groups (P < 0.05). Compared with the sufentanil group, the postoperative nausea and vomiting, dizziness and total adverse reactions in the esketamine group and FICB group were lower (P < 0.05).ConclusionPatient-controlled intravenous analgesia with esketamine has the potential to provide good postoperative analgesia for total hip arthroplasty patients, reduce the incidence of adverse reactions after the operation, improve the satisfaction of patients and surgeons, and significantly improve patients’ postoperative mood.Trial registration: ChiCTR2300069632 (https://www.chictr.org.cn/) (March 22th, 2023).

Analysing the effect of physical exercise on social anxiety in college students using a chained mediation model

To explore the mechanism of physical exercise’s influence on college students’ social anxiety and to analyze the chain-mediated role of mindfulness and mental toughness. A questionnaire survey was conducted on 1071 Chinese college students using the Physical Exercise Rating Scale, Social Anxiety Self-Rating Scale, Positive Thoughts Scale, and Mental Toughness Scale. The direct effect value of physical exercise on college students’ social anxiety was − 0.042, the effect values of positive thoughts and mental toughness between physical exercise and college students’ social anxiety were − 0.078 and − 0.007, respectively, and the chain mediation effect of positive thoughts and mental toughness was significant, with an effect value of -0.040. (1) Physical exercise significantly positively predicts positive thoughts and mental toughness and significantly negatively predicts social anxiety; (2) physical exercise has a significant direct and indirect effect on social anxiety in college students. Physical exercise can significantly predict college students’ social anxiety through the independent mediation effect of mindfulness and mental toughness and the chain mediation effect of mindfulness and mental toughness.

Effect of incentive nursing care on perioperative depression and anxiety in thyroid cancer: A systematic review and meta-analysis.

This study aimed to investigate the effect of incentive nursing care (ICN) as a supplementary therapy to routine nursing care (RNC) on depression and anxiety (DA) in patients undergoing thyroid cancer (TC) surgery during the perioperative period (PPP). A thorough search was conducted across various electronic databases, including PubMed, EMBASE, Cochrane Library, Chinese Biomedical Literature Database, WANGFANG, and China National Knowledge Infrastructure, spanning from their inception to October 1, 2023. The inclusion criteria were limited to randomized controlled trials focusing on the effects of ICN and RNC on DA in TC surgery during PPP. The primary outcomes assessed were depression, using the Self-Rating Depression Scale, and anxiety, measured by the Self-Rating Anxiety Scale. Additionally, the influence of ICN and RNC on the overall quality of life of the patients was evaluated using the Quality of Life Questionnaire-Core 30. Statistical analysis was carried out using RevMan 5.4 software. This meta-analysis incorporated a total of 12 eligible trials encompassing 999 patients. The findings indicated that the combination of ICN and RNC yielded superior outcomes compared to RNC alone across various measures. Specifically, ICN plus RNC demonstrated significant improvements over RNC alone in terms of the Self-Rating Depression Scale (P < .001), Self-Rating Anxiety Scale (P < .001), and Quality of Life Questionnaire-Core 30 (physical function, role function, cognitive function, emotional function, social function, and overall quality of life) (P < .001). The findings of this study demonstrate the considerable benefits of implementing ICN and RNC in the management of DA among patients with TC during PPP. However, it is crucial to interpret these results cautiously in light of the aforementioned limitations.

Comprehensive nursing interventions enhance sleep quality in patients with arrhythmia following AMI.

This study aims to assess the impact of comprehensive nursing care on sleep quality and rehabilitation duration in patients experiencing arrhythmia after acute myocardial infarction (AMI). Eighty-four patients with post-AMI arrhythmia treated at our hospital from February 2018 to February 2019 were selected and divided based on the nursing care received. The observation group (n = 44) underwent comprehensive nursing interventions, while the control group (n = 40) received standard nursing care. Evaluations of cardiac function indices and sleep quality were conducted before and after the nursing interventions. In addition, comparisons were made between the 2 groups regarding arrhythmia occurrence, patient compliance during care, visual analog scale scores for pain, self-rating anxiety scale scores, self-rating depression scale scores, and overall nursing satisfaction. Following the nursing interventions, the observation group exhibited a significant increase in cardiac output, unlike the control group, which showed no notable change. Both groups demonstrated significant improvements in left ventricular end-diastolic dimension and left ventricular ejection fraction; however, these enhancements were more pronounced in the observation group. Post-intervention, the Pittsburgh Sleep Quality Index scores were significantly lower in the observation group compared with the control group, indicating better sleep quality. The observation group also experienced a significant reduction in the incidence, frequency, and duration of arrhythmia episodes. Furthermore, this group showed a lower incidence of complications during the intervention period and reported lower visual analog scale, self-rating anxiety scale, and self-rating depression scale scores after nursing care. Nursing satisfaction rates were notably higher in the observation group than in the control group. Comprehensive nursing care significantly enhances sleep quality, speeds up rehabilitation, and increases patient satisfaction in individuals with arrhythmia after AMI. These findings support the clinical adoption of comprehensive nursing interventions for this patient population.

The mediating effect of clinical belongingness on the relationship between anxiety and professional identity in nursing interns: a cross-sectional study

BackgroundPrevious studies have reported that anxiety negatively affects professional identity (PI), and clinical belongingness is positively correlated with PI among nursing interns. However, little is known about the relationship between anxiety, PI, and clinical belongingness among nursing interns.ObjectiveTo explore the relationship between PI, clinical belongingness, and anxiety among nursing interns, and to demonstrate the mediating role of clinical belongingness in this relationship.MethodsA cross-sectional study using an online questionnaire was conducted between November 2023 and January 2024 among 1,050 nursing interns from 26 teaching hospitals in Sichuan Province, China. A general information questionnaire, the Belongingness Scale-Clinical Placement Experience (BES-CPE), the Self-Rated Anxiety Scale (SAS), and the Professional Identity Questionnaire for Nursing Students (PIQNS) were used to collect data. SPSS (version 25.0) and AMOS (version 28.0) were used to analyze the data.ResultsNursing interns had moderate mean scores for all variables; PI (60.77 ± 12.18), clinical belongingness (115.99 ± 17.02), and anxiety (47.44 ± 8.75). Correlation analyses revealed that both PI (r = −0.129, p &amp;lt; 0.01) and clinical belongingness (r = −0.087, p &amp;lt; 0.01) were negatively correlated with anxiety and clinical belongingness was positively correlated with PI (r = 0.601, p &amp;lt; 0.01). The clinical belongingness of nursing interns had a mediating effect on the relationship between anxiety and PI (β = −0.072, 95% confidence interval = −0.133 to −0.013, p &amp;lt; 0.001), accounting for 40% of the total effect.ConclusionThe anxiety level of nursing interns can have a direct impact on the prediction of PI and an indirect influence on PI mediated by clinical belongingness. Accordingly, nursing educators and managers should screen and channel the mental health problems of nursing interns in a timely manner, improving their clinical belonging, which will help improve PI and ultimately improve the stability of the nursing workforce.

Impact of family care on sleep quality in perimenopausal women: mediating roles of anxiety and depression

BackgroundThis study aimed to investigate the relationship between family care, anxiety, depression, and sleep quality in perimenopausal women. Furthermore, it also aimed to examine the role of anxiety and depression in mediating family care and sleep quality. The study findings aim to provide theoretical support for alleviating anxiety and depression levels and improving sleep quality in perimenopausal women.MethodsPerimenopausal women (n = 860) in Gansu Province were surveyed using the self-rating scale of sleep, self-rating anxiety scale, self-rating depression scale, and family adaptation partnership growth affection resolve.ResultsThe sleep quality, anxiety, and depression scores of the perimenopausal women in Gansu Province were 25.33 ± 5.00, 40.74 ± 10.89, and 40.77 ± 10.03, respectively, and the family care score was 6.64 ± 2.36. Family care was negatively correlated with sleep quality, anxiety, and depression scores; anxiety was positively correlated with depression and sleep quality scores, and depression was positively correlated with sleep quality scores. Anxiety and depression in perimenopausal women partially mediated family care and sleep quality, with mediating effects accounting for 15.74% and 60.69% of the total effect, respectively.ConclusionAnxiety and depression are mediating variables between family care and sleep quality in perimenopausal women. It is recommended that hospital and community staff pay attention to the role of good family care in perimenopausal women, actively implement intervention strategies aimed at reducing anxiety and depression pathways, and improve their sleep quality.

Influenza vaccination hesitancy and related factors among pregnant and breastfeeding women: A cross-sectional study

ABSTRACT Achieving safe influenza vaccination coverage among pregnant and breastfeeding women is a global health goal due to the potential risks of serious influenza for both mother and child. However, vaccine hesitancy remains a significant barrier to vaccination uptake. Since anxiety represents a determinant in vaccine decision-making, this study aimed to assess influenza vaccination hesitancy and anxiety levels in this population and to explore the association between women’s characteristics, their reluctance, and anxiety levels. A multicentre, cross-sectional study was conducted between February and June 2022 using structured phone interviews to assess: (1) socio-demographics and clinical history; (2) anti-flu vaccination status, previous anti-flu vaccination, and Sars-CoV-2 infection history; (3) insights into influenza vaccination during pregnancy; (4) attitudes toward anti-flu vaccination, using the Vaccination Attitudes Examination (VAX) Scale; (5) anxiety levels, measured by the Self-Rating Anxiety Scale (SAS). Among the 387 participants, 22.8% were already vaccinated or expressed willingness to be vaccinated against influenza, and 54% had an anxiety disorder. While anxiety was not significantly associated with vaccine hesitancy, ongoing pregnancy emerged as an independent predictor of anxiety. Higher educational levels, ongoing pregnancy, already being vaccinated or willingness to get vaccinated, and being employed were associated with reduced vaccine hesitancy, while prior SARS-CoV-2 infection with increased hesitancy. Fear of unpredictable events and lack of healthcare professionals’ recommendations emerged as reasons for vaccine reluctance. Given the low coverage rates, these findings highlight the need for health services to enhance vaccination efforts and provide clear recommendations to counter misinformation and ensure accurate vaccine safety information.

Change in sleep, gastrointestinal symptoms, and mood states at high altitude (4500m) for 6 months.

This study aimed to investigate the alterations in sleep quality and sleep patterns among military personnel at altitudes ranging from 1500 to 4500m, as well as the associated factors influencing their sleep. This study employed a longitudinal prospective survey conducted over a period of six months, from November 2023 to June 2024. A total of 90 soldiers were recruited for participation. Initially, demographic data and sleep conditions were collected through a questionnaire administered to participants at an altitude of 1,500m. Subsequently, participants were monitored continuously to gather data over seven days at an altitude of 4,500m, specifically during the 7 days of the 6-month survey period), and the 1st month at an altitude of 4,500m (on the 1st month of the six-month survey period. Spearman's rank correlation was utilized to investigate the relationships among sleep quality, gastrointestinal symptoms, and mood states. The total score of the Pittsburgh Sleep Quality Index (PSQI) exhibited an increase, indicating impaired sleep quality among soldiers stationed at an altitude of 4,500m for durations 7 days, 1 month, 3 months, and 6 months. Notably, after 7 days of soldiers, there was a significant gradual in the number of military soldiers experiencing gastrointestinal symptoms, such as diarrhea, abdominal distention, and constipation, which subsequently stabilized with prolonged exposure to the altitude. Furthermore, a significant rise in the incidence of depression was observed after days of rapid exposure 4,500 above sea level, and the emotional state of military personnel tended to tend towards mild depression over the duration of time Correlation. Correlation analysis showed that the PSQI score was closely related to the Athens Insomnia Scale(AIS) total score, Epworth Sleepiness Scale(ESS) total score, Self-Rating Anxiety Scale(SAS) total score, Self-Rating Depression Scale(SDS) total score, difficulty in falling asleep, easy to wake up or wake up early at night, poor breathing and snoring (on the 1st month, the 3rd month and the 6th month at the altitude of 4500m respectively: rs = 0.868, 0.648, 0.483, 0.459, 0.472, 0.364, 0.613, 0.75; rs = 0.856, 0.521, 0.481, 0.354, 0.768, 0.720, 0.511, 0.535; rs = 0.756, 0.490, 0.496, 0.352, 0.708, 0.737, 0.424, 0.408, p < 0.01 or p < 0.05); Positively correlated with heart rate (at 4500m 7 days at altitude: rs = 0.233, p = 0.027), diarrhea (at 4500m 1-month at altitude: rs = 0.237) bloating and constipation (at 4500m 1 month and 3months respectively: rs = 0.472; rs = 0.364; rs = 0.341, 0.273, p < 0.05); and with age, sex, marital status, education were significantly positive correlation (rs = 0.463, 0.251, 0.255, 0.230, p < 0.05). The impaired sleep quality, gastrointestinal symptoms, and anxiety and depression in military personnel changed with the extension of the time of stationing at 4500m altitude, which was most prominent when stationed at high altitude for 7 days; the sleep quality of those stationed at high altitude had a close relationship with the gastrointestinal symptoms, the type of sleep(insomnia and drowsiness), and the heart rate, but it varied with the duration of the stationing at high altitude; our study provides new information for the prevention of sleep disturbance, gastrointestinal symptoms, and negative emotions in high-altitude military personnel.

The Impact of Improved and Refined Education on Anxiety After Interventional Surgery for Cerebrovascular Disease

Objective: To explore the impact of modified and refined health education on anxiety among patients undergoing interventional therapy for cerebrovascular diseases. Methods: Eighty patients with cerebrovascular diseases who underwent interventional therapy at the hospital from June 2023 to June 2024 were selected as the study subjects. They were divided into an observation group and a control group according to the random number table method, with 40 patients in each group. The control group received conventional health education, while the observation group received modified and refined health education. The Self-Rating Anxiety Scale (SAS) scores were compared between the two groups after the procedure. Results: There were no significant differences between the two groups in terms of gender, age, education level, and duration of illness (P &gt; 0.05). The SAS score in the observation group was significantly lower than that in the control group, showing a highly significant correlation (P &lt; 0.001). Conclusion: Modified and refined health education can effectively reduce anxiety levels among patients undergoing interventional therapy for cerebrovascular diseases and improve their quality of life, making it worthy of clinical promotion and application.

The clinical effects of continuous nursing intervention combined with chronic disease management center in patients with severe hypertension.

The construction and application of chronic disease management centers are increasing. However, the effect of continuing nursing combined with intervention measures provided by chronic disease management centers in patients with severe hypertension is still unclear. To analyze the application effect of continuous nursing intervention combined with chronic disease management center in patients with severe hypertension. 240 patients with severe hypertension were randomly divided into control group (N = 120) and study group (N = 120). The study group adopted the intervention measures of continuous nursing combined with chronic disease management center, while the control group adopted routine nursing. The nursing effects of the 2 groups were compared. After nursing, the short form 36-item health survey, total satisfaction rate and medication compliance rate of the study group were higher than those of the control group (P < .001). Blood pressure, self-rating anxiety scale, and self-rating depression scale scores were lower than those of the control group (P < .05). Continuing nursing combined with the intervention of chronic disease management center can effectively reduce the blood pressure of patients with severe hypertension, and the overall nursing effect is remarkable.

Application of midnight-noon ebb-flow combined with five-element music therapy in continuous nursing of patients with chronic wounds.

To investigate the effect of Midnight-noon Ebb-flow combined with five-element music therapy in the continuous nursing of patients with chronic wounds. From March 2022 to November 2023, we recruited 50 eligible chronic wound patients and randomly divided them into two groups according to a random number table: the experimental group (n = 25) and the control group (n = 25). The control group was treated with conventional nursing measures. The experimental group received Midnight non Ebb flow Combined with Five element Music Therapy on the basis of the control group. The Self Rating Anxiety Scale (SAS) of the experimental group (39.71 ± 4.30 points vs. 50.29 ± 3.54 points, t = 4.927，p < 0.001)、The Self Rating Depression Scale (SDS) (42.09 ± 6.23 points vs. 53.98 ± 3.50 points, t = 5.381，p < 0.001)、 The total score of the Pressure Ulcer Healing Scale (PUSH) (2.12 ± 3.71 points vs. 4.80 ± 3.76 points, t = 2.535, p = 0.015) was lower than that of the control group; The total score of the 36 item Short Form Health Survey (SF-36) (102.88 ± 5.88 vs 92.48 ± 6.99 points, t = -5.692, p < 0.001) was higher than that of the control group; Comparing the VAS scores of two groups of patients on days 1, 3, and 7, it was found that the control group was higher than the observation group at all three time points; Secondly, the effective rate of wound healing in the experimental group was higher than that in the control group (92% vs 68%, x2 = 4.500, p = 0.034). Midnight-noon Ebb-flow combined with five-element music therapy is a nursing intervention program with considerable benefits for the treatment of chronic wounds, such as effective progress in wound health outcomes, alleviation of patients' anxiety, depression, and pain symptoms, and consequently improvement in quality of life.

The Efficacy of Implementing Labor Analgesia Education via the WeChat Public Platform—A Randomized Controlled Study

Background: Previous research has revealed that utilizing videos or images to educate primiparas about labor analgesia yields significantly superior results. WeChat supports various types of media, making it an ideal carrier for educational content. We have established a WeChat public account where educational content is presented through videos, images, and relevant scientific articles. We will investigate the effectiveness of WeChat public platform in primiparas analgesia education. Methods: Primiparas were randomly assigned to either the WeChat public account education group (W group) or traditional bedside education group (B group). The labor analgesia knowledge questionnaires, self-rating anxiety scales, and the time taken for positioning were compared between the two groups. Additionally, satisfaction with labor analgesia was evaluated post-delivery. Results: A total of 90 primiparas were completed the study. Compared to the B group, primiparas in the W group had higher scores on labor analgesia knowledge questionnaire (55 ± 11.1 vs. 65 ± 9.2, p = 0.001), lower anxiety scores (51.4 ± 5.4 vs. 48.9 ± 4.6, p = 0.02), shorter positioning time (27.5 ± 7.9 s vs. 20.1 ± 9.2 s, p = 0.001) than those in the B group. The satisfaction of anesthesiologists with body positioning and the satisfaction of primiparas with labor analgesia were similar between the two groups. Conclusions: The use of WeChat public platform for labor analgesia education can enhance primiparas understanding and cooperation during the procedure, decreasing maternal anxiety. It also benefits anesthesiologists by improving work efficiency. It has significant clinical value and promising prospects for promotion. Clinical Trial Registration: The study was registered with the Chinese Clinical Trial Registry (ChiCTR1900025231).

Altered regional brain activity and functional connectivity in relation to blood lead levels

BackgroundLead is a prevalent heavy metal pollutant in the environment, and chronic lead exposure in occupational settings has been linked to cognitive decline. Our objective was to delineate lead-induced changes in brain functional activity through the assessment of regional homogeneity (ReHo), degree centrality (DC) and seed-based functional connectivity (FC) using resting-state functional magnetic resonance imaging (rs-fMRI).MethodsIn this cross-sectional study, we recruited 76 participants from a smelting company. Based on their blood lead levels, 26 participants were assigned to the lead exposure group (≥ 300 μg/L), whereas 23 were assigned to the control group (≤ 100 μg/L). Neuropsychological assessments included the Montreal Cognitive Assessment, Mini-Mental State Examination, Self-rating Anxiety Scale, and Self-rating Depression Scale. Participants underwent rs-fMRI for ReHo, DC, and FC analyses. Brain regions demonstrating significant differences in ReHo and DC were identified as regions of interest for subsequent FC analysis. We also examined the relationships between lead levels, FC values, and neuropsychological scores.ResultsCompared to the control group, individuals with high lead exposure exhibited increased ReHo in the bilateral insula and vermis and elevated DC in the left olfactory cortex. Notably, the left insula demonstrated reduced FC with the right cerebellar crus I, left fusiform gyrus, left superior frontal gyrus, and left middle frontal gyrus. The right insula also displayed reduced FC with the right middle frontal gyrus but increased FC between the left olfactory cortex and right insula. Furthermore, negative correlations were observed between lead levels and FC of the left insula with the left fusiform gyrus (r = − 0.586), left superior frontal gyrus (r = − 0.556), and left middle frontal gyrus (r = − 0.626), as well as between FC of the right insula and the right middle frontal gyrus (r = − 0.587). Conversely, there was a positive association between FC of the left olfactory cortex with the right insula and lead levels (r = 0.609), whereas an inverse relationship was noted with neurocognitive assessments.ConclusionsThe disruption in insula coordination may significantly impair long-range FC and contribute to cognitive deficits resulting from lead exposure. The insula appears to be a pivotal region in lead-associated neurocognitive impairment.

The Role of Mindfulness Decompression Therapy in Managing Acute Stress Disorder in Traumatic Fracture Patients.

Traumatic fractures are common orthopedic injuries with higher incidence globally, leading to acute stress disorder (ASD). Therefore, this study aimed to analyze the clinical outcomes of mindfulness-based stress reduction (MBSR) therapy in patients with traumatic bone fractures suffering from ASD. This study included 135 patients who underwent trauma and fracture treatment at The 305th Hospital of the PLA between August 2021 and August 2023. Based on their participation in MBSR therapy, they were categorized into a conventional group (n = 62) and a combined group (n = 73). We comparatively analyzed the ASD Scale (ASDS), Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS), Self-Rating Sleep Status Scale (SRSS), and World Health Organization Quality of Life (WHOQOL) measurement-BREF (WHOQOL-BREF) scores between these two experimental groups. Furthermore, we assessed the incidence of ASD after treatment between these two groups. There were no significant differences in gender, age, body mass index, education, income, type of expense, trauma type, marital status, fracture site, diabetes status, hypertension status, and the pain visual analog scale (VAS) score, activities of daily living (i.e., modified Barthel index) score, and Social Support Rating Scale score between the two experimental groups (p > 0.05). Moreover, no significant differences were found in the prevalence of ASDS before treatment between these two groups (p > 0.05). However, after treatment, the ASDS score was significantly lower in the combined group than in the conventional group (p < 0.05). Furthermore, post-management analysis revealed that the incidence rate of ASD was 24.19% in the conventional group and 8.22% in the combined group. Moreover, the incidence of ASD was significantly lower in the combined group compared to the conventional group (p < 0.05). Before intervention, the difference in the SAS or SDS between patients was not statistically significant (p > 0.05). However, following treatment, the SAS and SDS scores of patients were significantly lower in the combined group than in the conventional group (p < 0.05). Similarly, after treatment, the SRSS scores of patients were substantially lower in the combined group than in the conventional group (p < 0.05). Furthermore, the WHOQOL-BREF score of patients was significantly greater in the combined group than in the conventional group (p < 0.05). MBSR therapy can significantly alleviate ASD in trauma and fracture patients. Furthermore, this approach can alleviate the incidence of ASD and reduce anxiety, depression, and negative emotions in patients. These positive effects collectively improve sleep quality and overall well-being of patients.

Psychological Status and its Influencing Factors of Staff in a District of Shenzhen: A Retrospective Study.

Anxiety, depression, and sleep disorders, as psychological and emotional diseases, have serious impact on people's physical and mental health, and receive increasing academic attention. This study aimed to examine anxiety, depression, and sleep disorder of staff in a district of Shenzhen and to provide the basis for the development of targeted intervention measures to improve the psychological status of cadres. Based on the psychological evaluation data of staff cadres in a district of Shenzhen City obtained from January to December 2020, a stratified sampling method was adopted to randomly select two streets and three communities in each street. A total of six communities were selected as investigation units. All participants filled out the Self-rating Anxiety Scale (SAS), Self-rating Depression Scale (SDS), and Pittsburgh Sleep Quality Index (PSQI). Chi-square test and multiple logistic regression analysis were performed using R4.2.0 statistical software. A total of 705 effective psychological assessment questionnaires were matched, and there were 71 (10.13%) positive results on SAS, 156 (22.13%) positive results on SDS, and 264 (37.45%) positive results on PSQI. Chi-square test results showed that the detection rates of anxiety and depression were significantly different among the staff cadres of different genders and different educational levels (p < 0.05). The detection rate of sleep disorder of government officials significantly differed among different age groups (p < 0.05). The logistic regression analysis showed that the detection rates of anxiety, depression, and sleep disorder of female cadres and workers were significantly higher than those of male cadres and workers (p < 0.05). The detection rates of anxiety and depression of the staff with bachelor's degree and graduate degree were significantly lower than those of the staff with a college degree or below (p < 0.05). The detection rates of anxiety and depression are different among staff of different genders and different education levels in a district of Shenzhen, where female staff and those with lower education levels have higher detection rates.

Research on the Anxiety and Depression of Patients with Mechanical Ocular Injuries: A Cross-Sectional Study.

The present study aimed to investigate the prevalence of anxiety and depression in patients with mechanical ocular injuries, and the effects of worry and resilience on anxiety and depression. Patients with one eye of mechanical ocular injuries and healthy residents were recruited from June 8, 2022, to March 1, 2023. All subjects participated in psychologically relevant questionnaires including the Self-rating Anxiety Scale(SAS), the Self-rating Depression Scale(SDS), the Connor- Davidson Resilience Scale (CD-RISC), and the Penn State Worry Questionnaire(PSWQ). Data were collected and subjected to statistical analysis. There were no significant differences in SAS and SDS total scores based on demographics (p>0.05) except for the subjective appraisal of the family economy (p<0.05). The SAS and SDS total scores and the positive rates of anxiety and depression in the ocular trauma group were significantly higher than those in the healthy control group (p<0.01). The positive rates of anxiety and SAS total scores of individuals with mild visual impairment were significantly higher than those with low vision (p<0.01) and blindness (p<0.05). There was no difference between the remaining groups. The positive rates of anxiety and SAS total score (36.5%, 45.92) of individuals with mild visual impairment were significantly higher than those with low vision (4.3%, 38.15) (p<0.01) and blindness (19.4%, 40.19) (p<0.05). There was no difference between the other groups. All effects of mechanical ocular injuries on anxiety and depression were significant (p<0.01). The indirect mediating effects on anxiety by worry alone, resilience alone, resilience, and worry were significant (p<0.01). The mediating indirect impact on depression by worry alone (p<0.01), worry and resilience (p<0.05) were significant while resilience (p>0.05) did not show a significant mediation effect. Patients with mechanical ocular injuries are prone to developing anxiety and depression with resilience and worry playing a mediating role.