In situ simulation is thought to offer a good learning environment due to the fact that it is carried out in real clinical practice. This study was performed to compare the effect of in situ simulation and simulated clinical immersion environment on cancer nursing students extravasation management. The study was carried out with a randomized controlled pretest-posttest comparative design. The participants were randomly assigned to either the simulated clinical immersion group (n=19) or the in situ simulation group (n=24). The study data were collected using Extravasation Management Knowledge Test, Objective Structured Clinical Assessment, Students’ Satisfaction and Self-Confidence Scale and the State Anxiety Inventory. The pre-posttest mean scores for the knowledge level and anxiety mean scores of the participants in the simulated clinical immersion group and the in situ group were not statistically significant (p˃.05). The satisfaction and self-confidence scale mean scores and the skill levels of the students in both settings were similar after the implementation (p˃.05). The students' knowledge, skills, anxiety, self-confidence and satisfaction were similar in both simulation-based learning environments. In situ simulation can be recommended for use in nursing education. Considering cost-effectiveness and resources, both simulation methods can be used.
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