ARTICLESFailure of vagotomy to reverse obesity in the genetically obese Zucker ratCA Opsahl, and TL PowleyCA Opsahl, and TL PowleyPublished Online:01 Jan 1974https://doi.org/10.1152/ajplegacy.1974.226.1.34MoreSectionsPDF (1 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformation Cited ByHistory of hypothalamic research: “The spring of primitive existence”Dissecting the Role of Subtypes of Gastrointestinal Vagal Afferents11 June 2020 | Frontiers in Physiology, Vol. 11Effects of vagal neuromodulation on feeding behaviorBrain Research, Vol. 1693Hepatic denervation and dyslipidemia in obese Zucker (fa/fa) rats2 July 2015 | International Journal of Obesity, Vol. 39, No. 11Chapter 23 History of neuroendocrinologyThe rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weightPhysiology & Behavior, Vol. 87, No. 2Subdiaphragmatic vagal deafferentation affects body weight gain and glucose metabolism in obese male Zucker (fa/fa) ratsBettina Ferrari, Myrtha Arnold, Richard D. 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Gram1 October 2005 | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Vol. 289, No. 4Efeito da vagotomia troncular em ratos injetados na fase neonatal com glutamato monossódico: estudo biométricoActa Cirurgica Brasileira, Vol. 16, No. 1From Lesions to LeptinNeuron, Vol. 22, No. 2ObesitySerotonin-depleting midbrain lesions do not prevent ovariectomy-induced weight gainPhysiology & Behavior, Vol. 50, No. 5Gastrin release in obese Zucker ratsRegulatory Peptides, Vol. 24, No. 2Experimental Obesity: A Homeostatic Failure due to Defective Nutrient Stimulation of the Sympathetic Nervous SystemVentromedial hypothalamic and paraventricular nucleus lesions damage a common system to produce hyperphagiaBehavioural Brain Research, Vol. 28, No. 3Effects of Gastrointestinal Surgery on Ingestive Behavior in AnimalsGastroenterology Clinics of North America, Vol. 16, No. 3Neural activity in hypothalamic and genetic obesity28 February 2007 | Proceedings of the Nutrition Society, Vol. 46, No. 1Experimental manipulations of eating: Advances in animal models for studying anorectic agentsPharmacology & Therapeutics, Vol. 34, No. 3Effect of paraventricular nucleus lesions on body weight, food intake and insulin levelsBehavioural Brain Research, Vol. 22, No. 3Serotonin-depleting midbrain lesions fail to mitigate hyperphagia and obesity in the Zucker fatty ratPhysiology & Behavior, Vol. 34, No. 1Validation of tests of completeness of vagotomy in ratsJournal of the Autonomic Nervous System, Vol. 9, No. 1Gastrointestinal factors in hunger and satietyNeuroscience & Biobehavioral Reviews, Vol. 6, No. 2The role of vagally-mediated hyperinsulinemia in hypothalamic obesityNeuroscience & Biobehavioral Reviews, Vol. 6, No. 2The role of the autonomic nervous system in hypothalamic feeding syndromesAppetite, Vol. 3, No. 2Regulation of energy balanc: studies on gnetic, hypothalamic and dietary obesity28 February 2007 | Proceedings of the Nutrition Society, Vol. 41, No. 2Brain-Stimulated Reward and Control of Autonomic Function: Are They Related?Hypothalamic-Pituitary Function in ObesityEvidence for vagal involvement in the eating elicited by adrenergic stimulation of the paraventricular nucleusBrain Research, Vol. 225, No. 2Effects of gastric vs complete subdiaphragmatic vagotomy on hypothalamic hyperphagia and obesityPhysiology & Behavior, Vol. 26, No. 2Development of food motivated behavior in free feeding and food restricted zucker fatty (fa/fa) ratsPhysiology & Behavior, Vol. 25, No. 4Development of VMH obesity in vagotomized ratsPhysiology & Behavior, Vol. 22, No. 1Hypothalamic hyperphagia prevented by prior subdiaphragmatic vagotomy: Insulin hyperphagia is unaffectedPhysiology & Behavior, Vol. 21, No. 5Hyperphagia and obesity following ventromedial hypothalamic lesions in rats with subdiaphragmatic vagotomyPhysiology & Behavior, Vol. 20, No. 5VAGOTOMY FOR TREATMENT OF SEVERE OBESITYThe Lancet, Vol. 311, No. 8059Effects of Adrenalectomy on Body Weight and the Size and Number of Fat Cells in the Zucker (Fatty) Rat7 August 2009 | Endocrine Research Communications, Vol. 5, No. 3Effect of caloric restriction on basal insulin levels and the in vivo lipogenesis and glycogen synthesis from glucose in the Koletsky obese ratMetabolism, Vol. 26, No. 7Abolition by selective gastric vagotomy of the influence of water temperature on water intake: Mediation via enhanced gastric clearancePhysiology & Behavior, Vol. 18, No. 6Meal patterns in the genetically obese zucker ratPhysiology & Behavior, Vol. 18, No. 4Origin of endocrine-metabolic changes in the weanling rat ventromedial syndromeJournal of Neuroscience Research, Vol. 2, No. 2Food motivated behavior in genetically obese and hypothalamic-hyperphagic rats and micePhysiology & Behavior, Vol. 13, No. 5 More from this issue > Volume 226Issue 1January 1974Pages 34-38 Copyright & PermissionsCopyright © 1974 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1974.226.1.34PubMed4809886History Published online 1 January 1974 Published in print 1 January 1974 Metrics