As the healthcare industry undergoes rapid digital transformation, the need for robust cybersecurity measures has never been more critical. AI-driven solutions, such as Machine Learning (ML) and anomaly detection, are proving to be pivotal in securing healthcare data. These technologies enable healthcare organizations to identify cyber threats proactively, automate incident response, and enhance data security. Furthermore, AI's ability to provide continuous network monitoring, predictive analytics, and real-time anomaly detection offers healthcare providers the tools needed to mitigate risks before they escalate. This research highlights the key applications of AI in healthcare data security, including its effectiveness in vulnerability management and regulatory compliance. It also delves into the ethical and operational challenges of integrating AI-driven threat detection systems into healthcare settings, including concerns related to bias in AI models, regulatory hurdles, and the complexity of AI system integration into existing healthcare infrastructures. In a 2023 study, Accenture reported that AI-based cybersecurity systems reduced detection and response time by up to 60%, illustrating how AI accelerates response to potential data breaches. Similarly, HIMSS noted that the risk of data breaches in healthcare could be halved by AI technologies that continuously monitor and analyze data. These findings emphasize AI's role in minimizing the delays and errors typically associated with human-driven responses. AI techniques such as supervised, unsupervised, and semi-supervised learning play a crucial role in anomaly detection. These models identify irregular patterns in healthcare systems, flagging potential threats even when subtle. For example, deep learning approaches, including Convolutional Neural Networks (CNNs) and Recurrent Neural Networks (RNNs), can uncover outliers in healthcare data, enhancing system security. The ability of AI to continuously learn from previous attacks ensures that systems evolve with emerging threats, further solidifying its place in healthcare cybersecurity. Additionally, AI aids in predictive analytics, which can forecast future cyber threats based on historical data, allowing healthcare providers to address vulnerabilities proactively. By leveraging such capabilities, AI not only safeguards sensitive patient data but also enables healthcare institutions to stay compliant with stringent regulatory standards like HIPAA and GDPR. However, AI implementation in healthcare security comes with its own challenges. Integrating AI into legacy systems requires substantial infrastructure upgrades, and the complexity of dynamic encryption can strain system resources. Furthermore, the ethical concerns surrounding AI, such as the transparency of decision-making processes and potential bias in AI algorithms, must be carefully managed to ensure equitable and effective security solutions