In its 800-year history, the University of Padova (Padua, Italy) has come to play an important role in the development of animal science in Italy and Europe. Having founded the oldest university botanical garden (1545; UNESCO World Heritage Site) and anatomical theatre (1595), and awarded the first university degree to a woman (Elena-Lucrezia Cornaro-Piscopia, 1678), the University instituted the Public School of Agriculture (Orto Agrario) in 1765 and the Collegium Zooiatricum in 1773. Between 1986 and 1995, under the leadership of Professor Mario Bonsembiante, animal scientist and rector, the scientific-technological center of Agripolis was established, including the Faculties of Agriculture and Veterinary Medicine (with the experimental farm and veterinary hospital), the Istituto Zooprofilattico delle Venezie, and Veneto Agricoltura. Agripolis rapidly became the most innovative center in Italy for teaching, research, and extension services in the fields of agricultural, animal, veterinary, food and environmental sciences. In the last 35 years, the number of Italian animal scientists has remained almost constant, but they have moved on to more innovative research topics closer to society’s demand and concerns, and significantly enhanced their international standing, reaching the first position in Europe and the fourth in the world in terms of citations.