The industrial revolution 4.0 requires learning that can develop various literacy skills of students so that they can succeed in learning as well as in everyday life. To answer the challenges of the industrial revolution 4.0, the education world seeks to apply 21st-century learning. Through 21st century learning, science learning can be carried out in an integrated manner supported by thematic learning. However, the real conditions illustrate that the application of thematic learning and the integration of literacy skills in science learning is still low. This happens because the integration of literacy in learning is still very limited. One solution that can be done to overcome this problem is to develop new integrated science teaching materials based on thematic learning based on thematic learning for grade VIII students. The type of this research was research and development. The development of integrated science teaching materials for new literacy based on thematic learning consists of seven stages, namely with potential and problems, information gathering, product design, product design, product validation, product testing, product improvement. The instrument for collecting data consisted of two. First, validity sheets are given to experts. Second, practicality sheets are given to teachers and students. Data analysis techniques used descriptive statistical analysis. Based on data analysis, two research results were obtained. The first validation of science teaching materials about integrated with new literacy and component of validity science learning is good and very good with an average value of 75,17 and 80.15. Second, the practicality of integrated science teaching materials for new literacy based on thematic learning according to teachers and students is very good with an average value of 89.85 and 83.53. Based on the results of the study, it can be indicated that integrated literacy teaching materials for new literacy based on valid and practical thematic learning and can be used in science learning.