The article is devoted to one of the most frequently faced crime investigation procedure – scene examination (investigation), during which an investigator and a specialist to recognize, record, collect, transport and store trace information before conducting expert examination. Their activity, in this case, consists of a number of main stages: the recognition of traces on the subjects, which at the time of the commission of crimes could have formed traces and which (subjects with traces) can be collected; the recognition of traces on the subjects, which cannot be collected; recording, collecting, packing of traces on the subjects and traces; transportation of collected subjects with traces and traces to the pre-trial investigation authorities, its storage until sending them to the institution of forensic examinations; samples’ obtaining for comparative examination; transportation of subjects with traces and traces and samples for expert research. These main stages constitute the technology of scene examination (investigation), which (technology), in the general context, is defined as a set of knowledge, information about the sequence of separate work operations in the production process of something. The analysis of the integration of the concept of “technology” in forensic science and forensic expertology showed that the general understanding of the term “technology” there is no classification of technologies, their structure and content, and the order of representation at a practical level for the implementation into crime investigation. The article illustrates some shortcomings of scene examination (investigation). The analysis of regulations that adjusting scene examination (investigation) shows that they do not have detailed instructions for the implementation of specific actions by specialists. In the opinion of the author, the solution of problematic issues should be the standardization of the institutions’ activities that provide for the conduct of scene examination (investigation) and expert research. The article briefly deals with the history of international standardization, the state of standardization in Ukraine, analyzes the provisions of the international standard ISO 21043-2: 2018 “Recognition, recording, collecting, transport and storage of items” (which have potential forensic significance). According to the results of the research, conclusions were made on the necessity of implementation into the work of the institutions that provide scene examination (investigation) and expert research, quality management systems in accordance with the requirements of ISO/IEC 17020 ISO/IEC 17025, as well as the harmonization of the international standard ISO 21043-2: 2018 as a national regulatory document (National Standards of Ukraine (DSTU)) with the further implementation into practical activities on crime detection. Key words: international standardization, ISO 21043-2:2018, standardization of the technology of scene examination (investigation).