Reflection from glasses is ubiquitous in daily life, but it is usually undesirable in photographs. To remove these unwanted noises, existing methods utilize either correlative auxiliary information or handcrafted priors to constrain this ill-posed problem. However, due to their limited capability to describe the properties of reflections, these methods are unable to handle strong and complex reflection scenes. In this article, we propose a hue guidance network (HGNet) with two branches for single image reflection removal (SIRR) by integrating image information and corresponding hue information. The complementarity between image information and hue information has not been noticed. The key to this idea is that we found that hue information can describe reflections well and thus can be used as a superior constraint for the specific SIRR task. Accordingly, the first branch extracts the salient reflection features by directly estimating the hue map. The second branch leverages these effective features, which can help locate salient reflection regions to obtain a high-quality restored image. Furthermore, we design a new cyclic hue loss to provide a more accurate optimization direction for the network training. Experiments substantiate the superiority of our network, especially its excellent generalization ability to various reflection scenes, as compared with state-of-the-arts both qualitatively and quantitatively. Source codes are available at https://github.com/zhuyr97/HGRR.