Russian Academy Of Sciences Research Articles

Target-point interpolation of a program control in the approach problem

For a no Krasovskii Institute of Mathematics and Mechanics, Ural Branch, Russian Academy of Sciences, 620108, Yekaterinburg, Russianlinear controlled system, a fixed-time approach problem is considered in which the target point location becomes known only at the start of motion. According to the proposed solution method, node resolving program controls corresponding to a finite collection of target points from the set of their admissible locations are computed in advance and a refined control for the target point given at the start of motion is determined via linear interpolation of the node controls. The procedure for designing such a resolving control is formulated in the form of two algorithms, one of which is run before the start of the motion, and the other is executed in real time while the system is moving. The error in the transfer of the system’s state to the target point by applying these algorithms is estimated. As an example, we consider the approach problem for a modified Dubins car model and a target point about which only a compact set of its admissible locations is known before the start of motion.

Uranium in groundwaters of North Kazakhstan

Relevance. The need to dentify the characteristics of the distribution of radioactive elements in the groundwater of Northern Kazakhstan. Aim. Generalization of available data on the geochemistry of groundwater and uranium and radon distribution in them using the example of the northern regions of the Republic of Kazakhstan. Methods. Generalization of long-term hydrogeochemical research and compilation of an electronic data bank on the territory of Northern Kazakhstan. A laboratory study of the chemical composition of groundwater was carried out at the Research Laboratory of Hydrogeochemistry of the School of Natural Resources Engineering of Tomsk Polytechnic University. Measurements of 222Rn contents in waters were carried out using the Alfarad Plus complex in the Laboratory of Hydrogeology of Sedimentary Basins of Siberia, Institute of Geology and Geography, Siberian Branch, Russian Academy of Sciences. Results. The groundwater of aquifers of different ages, distributed in the territory of Northern Kazakhstan (North Kazakhstan uranium province), was studied. Two geochemical sets of groundwater were identified. The first is characterized by the dominance of HCO3– and Mg2+ in the water composition, and the second by Cl– and Na+. A change in composition and an increase in the value of total mineralization from 0,1 to 49 g/dm3, in the direction from north to south, indicate the development of continental salinization. In natural waters of the first group, uranium content varies from 0.065 to 16000 μg/dm3 and radon activity from 4 to 3885 Bq/dm3. For sodium chloride waters of the second set, concentrations can reach 32500 μg/dm3, and radon activity is 6–59 Bq/dm3, since the emanating reservoir (granitoids) is located to the north – at a distance of 80–100 km. Naturally, granitoid massifs of the studied region are sources of uranium. Their drainage by the river network leads to its removal and concentration on geochemical barriers in the groundwater of the Neogene-Quaternary aquifer. This distribution of radioactive elements is associated with the high migration ability of uranium in solution in the form of uranyl ion in oxidizing geochemical conditions.

African historical studies: challenges and opportunities of source studies. Rec. ad. op.: Sources on the history of Africa: problems, trends, prospects for study and application / col. monograph under the general note by A.S. Balezin. Moscow: Institute of World History, Russian Academy of Sciences, 2023. 339 p.

African historical studies: challenges and opportunities of source studies. Rec. ad. op.: Sources on the history of Africa: problems, trends, prospects for study and application / col. monograph under the general note by A.S. Balezin. Moscow: Institute of World History, Russian Academy of Sciences, 2023. 339 p.

Key Anabolic Markers in Human M. Soleus after 21-Day Head-Down Tilt Bedrest

Prolonged bed rest can have a significant negative effect on skeletal muscle, leading to muscle wasting and reduced strength. This process can occur in as little as 10 days in healthy individuals, with the loss of muscle mass and strength being particularly pronounced during the first week of immobilization. Head-down tilt bed rest (HDT) is a method used to simulate the physiological changes that occur in weightlessness during spaceflight. This technique involves lying in bed with the head tilted downward. This paper is dedicated to the analysis of key anabolic markers of the soleus muscle during 21 days of HDT BR. The HDT BR experiment was conducted at the Institute of Biomedical Problems, Russian Academy of Sciences. Six healthy male volunteers, aged 25–35 years, were subjected to 21 days of strict bed rest with a tilt angle of –6°. A needle biopsy of the m.soleus was performed using the Bergström method before the start of HDT BR and on day 21 of HDT BR. The biopsy material was immediately frozen in liquid nitrogen for further Western blot and PCR analysis. Examination of mTORC1 substrates showed a significant decrease in p70 and 4EBP1 phosphorylation after HDT BR. We also observed a significant decrease in the phosphorylation of another ribosomal kinase, p90RSK, a significant increase in eEF2 phosphorylation and an increase in eEF2k mRNA expression. In addition, the phosphorylation of AMPK and its substrate ACC decreased after HDT BR. The data obtained in this work support the hypothesis that a decrease in protein synthesis, together with an increase in proteolysis, contributes to the development of human m. soleus atrophy after 21 days of HDT BR.

Research Institute of Internal and Preventive Medicine, Branch of the Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences

The purpose of the study was to evaluate the clinical manifestations of osteoarthritis (OA) in combination with MS (OAMS) and their relationship with concentration of several circulating proinflammatory cytokines, the level of lipids in peripheral blood serum. Forty women patients with knee OA were examined: 19 patients from the experimental group in whom OA was combined with metabolic syndrome (MS), 21 patients with OA without MetS. All patients were elderly and overweight. In the first subgroup of patients, the absolute majority of people were obese, while in the second subgroup, overweight patients predominated. Patients in the experimental subgroup showed a statistically significant increase in waist circumference compared to patients without MS. The duration of OA did not differ in both subgroups. It has been established that the metabolic phenotype of gonarthrosis – OA in combination with metabolic syndrome – differs from patients with OA without MS in greater severity of pain, a decrease in the level of daily activity, an increase in the burden of the disease and other symptoms of OA. These core characteristics are associated with poor quality of life and clinically significant symptoms of depression. The metabolic type of gonarthrosis is characterized by more pronounced laboratory signs of systemic low-grade inflammation in comparison with patients without MS, as evidenced by a threefold increase in CRP content and an increase in the level of IL-6, IL-18 in PC serum. In addition, in patients with the metabolic phenotype of OA, a fivefold increase in the level of a specific humoral immune response to type 2 collagen (Col2Ab) and dyslipidemia – an increase in the content of LDL cholesterol and triglycerides, with a comparable reduced level of HDL cholesterol – were revealed. It is concluded that the phenotype of OA in combination with MS is probably due to the pathogenetic similarity of OA and MS (syntropy), which is based on low-grade inflammation. Studying the pathogenesis of the OAMS phenotype and developing new principles for the treatment of multimorbidity should be based on patient-oriented approaches.

Results of long-term studies of the annual growth of mosses of the genus <i>Sphagnum</i> L. In the central taiga of Karelia

The studies were carried out on the territory of the Kindasovo forest-bog research station of the Karelian Research Center, Russian Academy of Sciences, located in the middle taiga subzone (61°48′ N, 33°35′ E). The experiments were carried out in the Nenazvannoe natural mesoeutrophic bog of the aapa type in seven permanent bog areas located in different ecological and coenotic conditions. The paper presents long-term results (from 10 to 38 years) of studies of the dynamics of annual growth of 11 widespread hygro- and hydrophilic species of Sphagnum mosses. Based on fluctuations in the average annual growth data during the years of study, the largest increases were observed for Sphagnum riparium (140 mm) and S. obtusum (93 mm), growing in heavily watered bog areas and not withstanding drying out; medium growths of S. fallax (65 mm), S. subsecundum (57 mm), S. majus (42 mm), S. balticum (36 mm), and S. warnstorfii (28 mm) are found in low-flow watered bogs, hollows, and on carpets; the lowest growth was shown for S. divinum (17 mm), S. centrale (15 mm), S. papillosum (12 mm), and S. fuscum (8 mm), growing on ridges, low hummocks, and carpets under conditions of sharply variable conditions hydration. A correlation analysis to study the influence of precipitation and average temperature on the annual growth of Sphagnum mosses did not show any significant dependence of moss growth on temperature during the growing season. For S. fuscum, S. obtusum, and S. warnstorfii, negative dependences on the temperature of individual months are observed in different months of the growing season. Precipitation during the growing season is the main factor determining the dependence of the annual growth of Sphagnum mosses. A significant dependence of annual growth on precipitation during the growing season was shown for species S. obtusum, S. papillosum, S. centrale, S. fallax, and S. subsecundum, while the significance was weak for S. divinum, S. fuscum, and S. majus.

Scholars from Russia and Southeast Asia Countries on the Present and Future of Mekong River

This is an overview of the conference “Mekong: Regional Challenges and Possible Solutions” organized by the Center for Vietnam and ASEAN Studies of the Institute of China and Contemporary Asia within Russian Academy of Sciences, and the Center for Scientific and Analytical Information of the Institute of Oriental Studies within Russian Academy of Sciences, with the support of the Gorchakov Foundation. The conference participants examined the geopolitical situation in the Greater Mekong Sub-region, assessed its resources, peculiarities of socio-economic development of individual states, summarized various opinions on sustainable development of the GMS, identified the main contradictions associated with the transboundary nature of the river, analyzed plans, the effectiveness of cooperation mechanisms between neighboring countries and external partners, as well as put forward proposals for solving existing problems with the participation of Russia.

Summer daily dynamics of the vertical structure of atmospheric aerosol over Baikal coastal area from ground-based lidar measurements

ABSTRACT The spatial structure of atmospheric aerosol over Baikal in summer is studied on a regular basis with the use of ground-based LOSA-M2 lidar measurements at the Boyarsky scientific station of the Institute of Physical Material Science, Siberian Branch, Russian Academy of Sciences (51.83°N, 106.06°E, 456 m a.s.l.), Republic of Buryatia, Russia. The lake is located in a basin surrounded by mountain ranges on all side; its water volume is large. The lidar data are analysed along with the regional meteorological situation and meteorological parameters of the atmosphere. The daily dynamics of aerosol distribution over the atmospheric is examined for the period from 2015 to 2023 accounting the effect of different air masses in the region. Three main typical air circulation types are identified for the coastal zone of southern Baikal in summer, which determine the atmospheric aerosol generation and transport. The first and most common type relates to breeze circulation, where the main changes in the spatial structure of aerosol occur in the 2–3-km layer and are determined by changes in the transport direction within a breeze cell during the day. The main feature of this type is a decrease in the altitude of an air layer which contains most of aerosol in the lower atmosphere up to 1 km. The second type refers to southwestern transport under the presence of an anticyclone over the region. The maximal altitude of the aerosol layers attains 7 km in this case. The most complex and dynamic changes in the daily spatial structure of atmospheric aerosol occurred under transport of cyclones and associated atmospheric fronts over Lake Baikal. Under this third type, the altitude of the aerosol layers decreases throughout the day within the altitude range from the surface to 3–4 km.

Особенности саморегуляции социокультурных девиаций молодежи

In the youth environment in transition conditions, processes related to the rethinking of life goals and ways of achieving them become more active. In social reality, deviant ways of achieving goals are presented in the form of meaningsjudgements, reflecting the principles of separation and self-assertion at the expense of others. In the article they are understood as sociocultural deviations. Their formation in social reality is conditioned by the contradictions forming in society. The selfregulation of sociocultural deviations is understood as a conscious choice by young people in their own self-determination of the principles of dissociation and selfaffirmation as optimal, from their point of view, in the emerging conditions of the ways of achieving the goals of life activity. Based on empirical research by the Centre for Sociology of Youth (Institute of Social and Political Research, Federal Research Centre for Sociology, Russian Academy of Sciences), the author considers the peculiarities of self-regulation of socio-cultural deviations of young people depending on their age, place of residence, religious identification, family and trust factor. Young people aged 15-17 are more often oriented in their life activities towards the choice in favour of sociocultural deviations than young people from older age groups. Respondents from low-income groups are more willing to use physical force in a dispute with opponents. In groups in which respondents conceptualise family as an instrumental value, young people are more likely to assert themselves at the expense of others and show disrespect for adults in order to achieve their goals than in groups in which family is conceptualised as a terminal value. Young people who do not trust others are more likely to focus on socio-cultural deviations to achieve their life goals, compared to respondents who build relationships with others on trust.

Искусственный интеллект как метафора, объект и субъект философского анализа

The article examines epistemological, ethical, anthropological, and other aspects of understanding self-learning programs called “neural networks” or “artificial intelligence”. The problematic nature of the latter is addressed in the research by reviewing three dozen studies of the idea of artificial intelligence, which were presented on April 4, 2024, at a joint scientific conference of the Center for Phe­nomenological Philosophy of the Russian State University for the Humanities and the Sector of Social Epistemology of the Institute of Philosophy, Russian Academy of Sciences. Based on the materials of the conference, this article examines artificial intelligence from the perspective of the history of philosophy and futurist literary images in comparison with human and other conceivable consciousness, both possessing free will as well as lacking it. Another aspect of this research provides an understanding of the problem areas of the theology of artificial intelligence and the place of artificial intelligence in modern theo­logy, as well as providing an analysis of the technical side of the implementation of existing and expected computer systems claiming to be “artificial intelli­gence”. The conference proved to be an important event for discussing philo­sophical and ethical issues related to the development of artificial intelligence and provided a platform for further research and understanding of the impact of AI on society and human individuality. This article outlines the general per­spective of the conference and, more specifically, selected theses

The gift of sanctions: an analysis of assessments of the Russian economy, 2022–2023

This essay analyzes a few prominent Western assessments, both official and private, of the effect of sanctions on the Russian economy and war effort during the first 18 months after February 2022. It seeks to understand the main goals of sanctions, alongside the facts and causal inferences behind the consensus view that sanctions were highly effective. Such understanding may then help to clarify the relationship between claims made by economist-observers outside Russia and those emerging from Russian sources – notably economists associated with the Russian Academy of Sciences (RAS) – which drew sharply different inferences from the same facts. We conclude that when applied to a large, resource-rich, technically proficient economy, after a period of shock and adjustments, sanctions are isomorphic to a strict policy of trade protection, industrial policy and capital controls. These are policies that the Russian government could not plausibly have implemented, even in 2022, on its own initiative. Sanctions were, in this sense, a gift to the Russian state and war effort.

Correction of microecological imbalance in children who have suffered from multisystem inflammatory syndrome associated with SARS‐CoV‐2 in the post‐rehabilitation period

To conduct a study of the quality of life of children who have suffered from multisystem inflammatory syndrome (MIS‐C) associated with SARSCoV‐2 in the post‐rehabilitation period against the background of correction of microecological imbalance.The study involved 49 children aged 2 to 12 years who underwent MIS‐C associated with SARS‐CoV‐2 and received treatment in a hospital (DGKB No. 3 in Novosibirsk), and then underwent rehabilitation on an outpatient basis. The duration of rehabilitation was 7–8 weeks. All children were prescribed a course of additional rehabilitation for 30 days in order to correct microecological imbalance, which included: Biovestin, a dietary supplement in liquid form, containing bifidobacteria of the Bifidobacterium longum MC‐42 strain; the official drug, Kudesan, (active ingredient Coenzyme Q10); and the official drug, Succinic Acid. The assessment of physical, social, educational, emotional and psychological functioning, as well as quality of life as an integrating indicator before and after a comprehensive rehabilitation course using the parental form of the Reds OL Generic Core Scales questionnaire (Russian version) was carried out.After the rehabilitation course, children who underwent MIS‐C associated with SARS‐CoV‐2 showed signs of dysfunction of various organs and systems, which may be the result of an imbalance in the microbial ecosystem and requires mandatory correction. The introduction of a probiotic product and drugs affecting metabolic processes into the rehabilitation course led to a decrease in inflammatory reactions, as well as normalisation of metabolic processes and increased oxygenation, which improved the condition of the children and their quality of life.Federal Research Center for Fundamental and Translational Medicine (FRC FTM), Siberian Branch, Russian Academy of Sciences

ISAND: AN INFORMATION SYSTEM FOR SCIENTIFIC ACTIVITY ANALYSIS (IN THE FIELD OF CONTROL THEORY AND ITS APPLICATIONS)

This paper describes the approaches underlying ISAND, an information system for scientific activity analysis in the field of control theory and its applications. ISAND is being developed at the Trapeznikov Institute of Control Sciences, the Russian Academy of Sciences. The ISAND ontology is oriented toward the representation and collection of knowledge in the field of control theory and its applications, namely, scientific knowledge (the ontology of control theory) and knowledge related to the scientific activity of agents (organizations, journals, conferences, and individual researchers) in this field. Based on this ontology, the ISAND architecture is a complex program system to collect, store, and analyze publications and their metadata from external sources. The ISAND algorithm for building the thematic profiles of scientific objects (publications, researchers, organizations, journals, and conferences), as well as ISAND text processing and network analysis capabilities, are presented. Finally, the main possibilities of using ISAND are considered.

The measure of proximity of conditional distance of institutional logic and discourse practice

According to the author's position, the modern direction of sociology of management considers the field of problems around the discourse activity of an individual and social groups formed under the influence of social institutions and organizations in the process of managing digital means of communication between them. The methodology of management processes research requires new approaches to empirical sociological research, assuming the predisposition of the subject to a typical perception of activity conditions and a certain reaction, which is conditioned by the formed worldview and practical activity, which corresponds to foreign studies of postinstitutionalism. According to the author of the article, in order to apply the cluster analysis of empirical data, it is necessary to introduce conditional distances between institutional logics and practices of discourse subjects, hereinafter referred to as discursants, in the format of the research hypothesis. The present empirical study is based on the analysis of video recordings of the scientific seminar "Philo sophy of Complexity" of the Institute of Philosophy of the Russian Academy of Sciences (RAS), posted on the Internet, N = 121 (2019–2024); the analysis of discourse participants on the video recording of the report at the scientific seminar "Philosophy and IT" of the Insti tute of Philosophy of the RAS, posted on the Internet, N = 13 (2023).

Газовый масс-спектрометрический анализ промышленных йогуртов

Food safety and quality are especially important in the dairy industry. Mass spectrometry is an effective tool of state control in this sphere. The research objective was to study the prospects for gas mass spectrometry with smart mathematical processing in assessing the composition and quality of dairy products. The study featured 11 samples of fresh and acidified yoghurts from different manufacturers and with various starters, functional food additives, etc. These samples and their packaging were evaluated using a small-sized quadrupole gas mass spectrometer MS7-200 with electron impact ionization developed at the Institute for Analytical Instrumentation, Russian Academy of Sciences. The data obtained were mathematically processed by the method of principal components. Based on the ratios of peak intensities at m/z = 55, 56, 57, 58, 59, 60, 61, 64, 67, 69, 70, 71, 72, 73, 74, 84, 85, and 88 Da, the fresh and expired samples were classified not only by the degree of freshness, but also by the composition and quality of the microbiological starters, raw materials, food additives, etc. In addition, some packaging materials proved to be of poor quality. In this study, the method of gas mass spectrometry was supplemented by the authentic methods for selecting gas emissions from yoghurts and packaging, accelerated acidification, and smart mathematical processing. The approach proved to be time-saving, sensitive, selective, available, and cost-effective. As a result, it demonstrated good potential as a means to control the composition and quality of dairy products and their packaging.

On the Composition of the Type Series of the Blanford’s Rock Gecko, <i>Bunopus blanfordii</i> Strauch, 1887 (Reptilia: Sauria: Gekkonidae)

Composition of the type series of gecko Bunopus blanfordii Strauch, 1887 is clarified based on original description and type specimens stored in the Zoological Institute, Russian Academy of Sciences, St. Petersburg. We designate ZISP 18290 as a lectotype.

НЕОБЫЧНЫЕ ПРЕВРАЩЕНИЯ АДДУКТА МИХАЭЛЯ ЛЕВОГЛЮКОЗЕНОНА И ЦИКЛОГЕКСАНОНА

Academician Genrikh Alexandrovich Tolstikov is a unique personality, a world-class scientist. During the years of his work as director of Institute of Organic Chemistry of the USC RAS (now the Ufa Institute of Chemistry of the Ufa Federal Research Center, Russian Academy of Sciences), new scientific directions were opened that are relevant and continue to this day. Research using sugars and anhydrous sugars, in particular, levoglucosane in the synthesis of prostaglandins and other bioactive structures, originates in the laboratory for the synthesis of low molecular weight bioregulators under the direction of prof. M.S. Miftakhov. After the creation of the laboratory for the synthesis of secondary metabolites (now the laboratory of pharmacophore cyclic systems) under the guidance of prof. Valeev F.A. Since the 90 s to the present, scientific research has been successfully conducted on the use of levoglucosenone and its derivatives in the synthesis of natural biologically active compounds and their analogues. Levoglucosenone attracted the attention of researches due to its availability and reactive, chiral structure. Its solubility in all organic solvents, and even in water, makes it a unique starting compound for organic synthesis. When describing the chemical behavior of levoglucosenone, it is important to note that many of its transformations proceed in a nontrivial manner and lead to unexpected products, which makes levoglucosenone an even more interesting object for study. Moreover, it turned out that the chemical transformations of its derivatives, in particular the Michael adducts of levoglucosenone and cycloalkanones, turned out to be even more unpredictable. This article is devoted to consideration of aspects of these transformations. Thus, it was found that two keto groups in the Michael adduct of levoglucosenone and cyclohexanone are not equivalent, the keto group of the carbohydrate fragment is more reactive. At the same time, when searching for the possibility of implementing intramolecular aldol condensation, it was unexpectedly found that the keto group of the carbohydrate fragment remains inert. Intramolecular carbocyclization could only be carried out in the Michael adduct of levoglucosenone and cyclododecanone. Based on the Michael adduct of levoglucosenone and cyclohexanone, a ten-membered lactone annelated with a carbohydrate fragment was synthesized. The problem of introducing substituents into the lactone cycle and modifying the carbohydrate part of the resulting lactone has been solved. On the basis of this adduct, an analog of the natural lactone, foracantholide, was synthesized. All results presented in the article include research conducted in our laboratory from 2014 to the present day.

Topical Research Led by Scientists of the Department of Agricultural Sciences, Russian Academy of Sciences

Topical Research Led by Scientists of the Department of Agricultural Sciences, Russian Academy of Sciences

The Relevance of the Engineering and Technical Solutions Implemented at the Branch of Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, and Current Problems of Vivariums and Laboratory Animal Breeding Facilities

The Relevance of the Engineering and Technical Solutions Implemented at the Branch of Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, and Current Problems of Vivariums and Laboratory Animal Breeding Facilities

Baikal Institute of Nature Management, Siberian Branch, Russian Academy of Sciences: Its Contribution to the Sustainable Development Strategy

Baikal Institute of Nature Management, Siberian Branch, Russian Academy of Sciences: Its Contribution to the Sustainable Development Strategy