Rotating Magnetic Field Research Articles

Unveiling the Biomedical Applications of Novel Coumarins Isolated From Capsicum Annuum L. Seeds by a Multivariate Extraction Technique.

For the first time, kinetic thermomagnetic extraction is a novel approach presented in this work. It required the application of four distinct variables: rotation speed (50, 75, and 100 rpm), magnetic field (0.8, 1.2, and 1.6 T), time interval (30, 60, and 90 min), and temperature (45, 55, and 65 °C). Numerous phytochemical categories were detected in the 81 crude chloroform extracts of green sweet bell pepper seeds that were collected, according to phytochemical analysis. Nine extracts were discovered to be linked to the coumarin chemical class and to have the same two extraction parameters: a 90-minute extraction duration and a 55 °C extraction temperature. To enable their coumarin contents to be chemically separated and chromatographically purified, two of these extracts containing coumarin were chosen. Four new phytocoumarins have been identified and their molecular structures distinguished using FTIR spectra, 1H-NMR, 13C-NMR, and mass analysis. By using MTT probing, it was discovered that these phytocoumarins exhibited anticancer activities against eight malignant populations and reduced oxidative stress in human SH-SY5Y populations. Similarly, the anti-inflammatory and antidiabetic properties were determined using three and two associated enzymes, respectively. The results demonstrated that the extracted phytocoumarins have exceptional oxidative stress-mitigating characteristics, ranging from 71.51 to 81.48 %, when compared to a positive control. Furthermore, they showed excellent cytotoxicity against the test malignant populations (IC50 values of 46.76-81.45 μg/ml). The isolates need to be taken into account as dual COX-2/5-LOX antagonists because they also showed a fascinating selective anti-inflammatory effect. The phytocoumarins under investigation have selectivity indices that are higher than those of the standards used, suggesting that they may have the ability to selectively block the COX2 enzyme that induces harmful inflammation. Compared to the standards, the phytocoumarins have a higher ability to block the catalytic activity of 5-LOX. This observation suggests that the phytocoumarins are powerful 5-LOX agents. Finally, they had a modest antidiabetic impact when tested against two blood-controlling enzymes. The authors came to the conclusion that the technique adopted is flexible and successful for extraction after modifying its components. Moreover, isolated phytocoumarins in general and natural-B1 in particular provide naturally derived solutions for oxidative stress and its associated diseases.

Evolution of the magnetic field rotation distributions in the inner heliosphere

The nature and evolution of the solar wind magnetic field rotations is studied in data from the Parker Solar Probe We investigated the magnetic field deflections in the inner heliosphere below 0.5 au in a distance- and scale-dependent manner to shed some light on the mechanism behind their evolution. We used the magnetic field data from the FIELDS instrument suite to study the evolution of the magnetic field vector increment and rotation distributions that contain switchbacks. We find that the rotation distributions evolve in a scale-dependent fashion. They have the same shape at small scales regardless of the radial distance, in contrast to larger scales, where the shape evolves with distance. The increments are shown to evolve towards a log-normal shape with increasing radial distance, even though the log-normal fit works quite well at all distances, especially at small scales. The rotation distributions are shown to evolve towards a previously developed rotation model moving away from the Sun. Our results suggest a scenario in which the evolution of the rotation distributions is primarily the result of the expansion-driven growth of the fluctuations, which are reshaped into a log-normal distribution by the solar wind turbulence.

Topological nano-switches in higher-order topological insulators

We consider multi-terminal transport through a flake of rectangular shape of a two-dimensional topological insulator in the presence of an in-plane magnetic field. This system has been shown to be a second-order topological insulator, thus exhibiting corner states at its boundaries. The position of the corner states and their decay length can be controlled by the direction of the magnetic field. In the leads we assume that the magnetic field is absent and therefore we have helical one-dimensional propagating states characteristic of the spin-Hall effect. Using a low-energy effective Hamiltonian we show analytically that, in a two-terminal setup, transport can be turned on and off by a rotation of the in-plane magnetic field. Similarly, in a three terminal configuration, the in-plane magnetic field can be used to turn on and off the transmission between neighbouring contacts, thus realising a directional switch. Analytical calculations are supplemented by a numerical finite-difference method. For small values of the Fermi energy and field strength, the analytical results agree exceptionally well with the numerics. The effect of disorder is also addressed in the numerical approach. We find that the switching functionality is remarkably robust to the presence of strong disorder stemming from the topological nature of the states contributing to the electron transport.

Investigating the influence of rotating magnetic field (RMF) on intermetallic compound crystallization, thermal and mechanical properties in lead-free Sn-Ag-Cu solder alloys during solidification

This research delves into the effectiveness of using rotating magnetic field (RMF) during the solidification process of Sn-3.5 wt% Ag-0.7 wt% Cu (SAC 357) alloy. The main goal is to evaluate the effect of RMF on the crystallization of intermetallic compounds (IMCs), as well as to study its implications for the thermal properties and creep resistance of the resulting alloy. It is found that the application of the RMF has a significant promotion effect on the improvement in the grain structure of the primary AgSn phase within the directionally solidified SAC 357 alloy. With the application of RMF, the morphology of the primary AgSn phase transformed from developed dendritic-like to fine needle-like, accompanied by a decrease in grain size, but shows no discernible impact on their composition. This observation is attributed to the influence of Lorentz force and thermo-electromagnetic convection. The implementation of a rotating magnetic field (RMF) resulted in notable enhancements in the thermal properties of the SAC357 solder alloy. Specifically, RMF application led to reductions in both the pasty range and melting temperatures, accompanied by a decrease in undercooling compared to conditions without stirring.The SAC357 alloy, when modified with a magnetic field, demonstrated the longest creep rupture time and higher creep resistance compared to those not subjected to magnetic field modification. This research endeavor aims to address a notable gap in our understanding concerning the behavior of SAC357 solder alloys when subjected to a Rotating Magnetic Field (RMF).

The effect of a rotating magnetic field on the antioxidant system in healthy volunteers - preliminary study.

Oxidative stress is characterized by an excessive concentration of reactive oxygen species (ROS) resulting from a disturbance in the balance between ROS production and their removal by antioxidant systems (SOD, CAT, GPx). Prolonged and intense oxidative stress can cause various forms of damage to cells, which markers are total antioxidant capacity (TAC), reactive oxygen species modulator (ROMO1), and malondialdehyde (MDA). It has been demonstrated that magnetic fields can positively affect human health, for example, by reducing oxidative stress. Determination of the effect of a rotating magnetic field (RMF) on the activity/concentration of selected oxidative stress markers. A group of 30 healthy volunteers (15 women and 15 men) (mean age 24.8 ± 5.1) in the study classified into the following groups: internal control group (CG);1h 25Hz (samples placed in the field for one hour at 25Hz); 3h 25Hz (samples placed in the field for 3h at 25Hz), the 1h 50Hz group ( placed in RMF for an hour at 50Hz), and a group of 3h 50Hz (samples placed in the field for 3h at 50Hz). Serum samples were collected in K2EDTA tubes.. The magnetic induction value obtained for RMF is 37.06 mT and 42.64 mT.Activity/concentration of selected oxidative stress markers was analyzed by ELISA. The influence of an RMF on the activity/concentration of SOD, MDA, TAC, and ROMO1 was demonstrated (p < 0.001; p = 0.0013; p < 0.001; p = 0.003). The RFM can reduce oxidative stress, as evidenced by higher SOD and CAT activities in the CG than in samples placed in the RFM. Prolonged exposure to the RFM at 50Hz increased the TAC level, indicating an intensification of oxidative stress in these samples. The optimal conditions for staying in the RFM (reducing oxidative stress) are 1h 50Hz for SOD and MDA; 3h 25Hz for CAT and TAC. In the case of ROMO1, it is stated that 1h 25Hz are the optimal conditions for no increased production of ROS.

Питание сверхпроводящих систем динамическим вращением трехфазного поля

In this work a device for powering superconducting systems by pumping magnetic flux is presented. The pumping is carried out by dynamic rotation of the 3-phase magnetic field in the motor stator, which has three pairs of coils.

How well does surface magnetism represent deep Sun-like star dynamo action?

Context. For Sun-like stars, the generation of toroidal magnetic field from poloidal magnetic field is an essential piece of the dynamo mechanism powering their magnetism. Previous authors have estimated the net toroidal flux generated in each hemisphere of the Sun by exploiting its conservative nature. This only requires observations of the photospheric magnetic field and surface differential rotation. Aims. We explore this approach using a 3D magnetohydrodynamic dynamo simulation of a cool star, for which the magnetic field and its generation are precisely known throughout the entire star. Methods. Changes to the net toroidal flux in each hemisphere were evaluated using a closed line integral bounding the cross-sectional area of each hemisphere, following the application of Stokes theorem to the induction equation; the individual line segments correspond to the stellar surface, base, equator, and rotation axis. We evaluated the influence of the large-scale flows, the fluctuating flows, and magnetic diffusion on each of the line segments, along with their depth-dependence. Results. In the simulation, changes to the net toroidal flux via the surface line segment typically dominate the total line integral surrounding each hemisphere, with smaller contributions from the equator and rotation axis. The surface line integral is governed primarily by the large-scale flows, and the diffusive current; the latter acting like a flux emergence term due to the use of an impenetrable upper boundary in the simulation. The bulk of the toroidal flux is generated deep inside the convection zone, with the surface observables capturing this due to the conservative nature of the net flux. Conclusions. Surface magnetism and rotation can be used to produce an estimate of the net toroidal flux generated in each hemisphere, allowing us to constrain the reservoir of magnetic flux for the next magnetic cycle. However, this methodology cannot identify the physical origin or the location of the toroidal flux generation. In addition, not all dynamo mechanisms depend on the net toroidal field produced in each hemisphere, meaning this method may not be able to characterise every magnetic cycle.

Parker Solar Probe Observations of Magnetic Reconnection Exhausts in Quiescent Plasmas near the Sun

Parker Solar Probe observations are analyzed for the presence of reconnection exhausts across current sheets (CSs) within R < 0.26 au during encounters 4–11. Exhausts are observed with nearly equal probability at all radial distances with a preference for quiescent Tp < 0.80 MK plasmas typical of a slow-wind regime. High Tp > 0.80 MK plasmas of a fast wind characterized by significant transverse fluctuations rarely support exhausts irrespective of the CS width. Exhaust observations demonstrate the presence of local temperature gradients across several CSs with a higher-Tp plasma on locally closed fields and a lower-Tp plasma on locally open field lines for an interchange-type reconnection. A CS geometry analysis directly supports the property that X-lines bisect the magnetic field rotation θ-angle, whether the fields and plasmas are asymmetric or not, to maximize reconnection rates and available magnetic energy. The CS normal width d cs distributions suggest that a multiscale reconnection process through nested layers of bifurcated CSs may be responsible for observed power-law distributions beyond the median d cs ∼ 1000 km with an exponential d cs distribution present for ion kinetic dissipation scales below this median. Magnetic field shear θ-angles are essentially identical at R < 0.26 and 1 au with medians at θ ∼ 55° near the Sun and θ ∼ 65° at 1 au. In contrast, the tangential flow shear distributions are different near and far from the Sun. A bimodal flow shear angle distribution is present near the Sun with strong shear flow magnitudes. This distribution is modified with radial distance toward a relatively flat distribution of weaker flow shear magnitudes.

The Effect of a Rotating Magnetic Field on the Regenerative Potential of Platelets.

Platelets are actively involved in tissue injury site regeneration by producing a wide spectrum of platelet-derived growth factors such as PDGF (platelet-derived growth factor), IGF-1 (insulin-like growth factor), TGF-β1 (transforming growth factor β), FGF (fibroblast growth factor), etc. A rotating magnetic field (RMF) can regulate biological functions, including reduction or induction regarding inflammatory processes, cell differentiation, and gene expression, to determine the effect of an RMF on the regenerative potential of platelets. The study group consisted of 30 healthy female and male volunteers (n = 15), from which plasma was collected. A portion of the plasma was extracted and treated as an internal control group. Subsequent doses of plasma were exposed to RMF at different frequencies (25 and 50 Hz) for 1 and 3 h. Then, the concentrations of growth factors (IGF-1, PDGF-BB, TGF-β1, and FGF-1) were determined in the obtained material by the ELISA method. There were statistically significant differences in the PDGF-BB, TGF-β1, IGF-1, and FGF-1 concentrations between the analyzed groups. The highest concentration of PDGF-BB was observed in the samples placed in RMF for 1 h at 25 Hz. For TGF-β1, the highest concentrations were obtained in the samples exposed to RMF for 3 h at 25 Hz and 1 h at 50 Hz. The highest concentrations of IGF-1 and FGF-1 were shown in plasma placed in RMF for 3 h at 25 Hz. An RMF may increase the regenerative potential of platelets. It was noted that female platelets may respond more strongly to RMF than male platelets.

Rotation impact on the radial vibrations of frequency equation of waves in a magnetized poroelastic medium

This research delves into the propagation of radial free harmonic waves in a poroelastic cylinder, conceptualized as a magnetically and rotationaly influenced hollow structure. The primary aim is to elucidate the magnetic field's and rotation impact on the vibrational behavior of such systems. The investigative method encompasses the resolution of motion equations, formulated as partial differential equations, through the application of Lame's potential theory. This analytical process is augmented by the implementation of fitting boundary conditions, culminating in the derivation of a comprehensive expression for the complex dispersion equation, predicated on the premise that the wavenumber embodies a complex entity. The precision of the model is corroborated through a comparative analysis with established literature, underpinned by an exploration of diverse scenarios. The research employed MATLAB for both numerical and graphical assessments, focusing on the dispersion and displacement attributes. Dispersion relations within the poroelastic medium were computed, considering varied magnitudes of magnetic field intensity, rotation and angular velocities. The outcomes are articulated through complex-valued dispersion relations, transcendental formulations, and numerical resolutions employing MATLAB's bisection technique. These insights hold substantial significance for the theoretical advancement in orthopedic research, particularly concerning cylindrical poroelastic media. This study deduces that the radial vibrational patterns and the corresponding frequency equation within a poroelastic medium are profoundly modified by the magnetic field's interference and rotation. This study formulate a novel governing equation for a poroelastic medium, highlighting the significance of radial vibrations and investigating the impact of magnetic field and rotation.

The Angular Velocity as a Function of the Radius in Molten Ga75In25 Alloy Stirred Using a Rotation Magnetic Field

The simulation of the solidification of alloys (like steel or aluminium alloys), which is carried out by using the melt flow induced by a rotation magnetic field (RMF), needs the correct angular velocity vs. the radius function of the melt. Because it is impossible to directly obtain information about the melt flow from industrial casting, this information can only be obtained from well-monitored experiments using low-melting-point metals or alloys (e.g., Hg, Ga, GaIn, and GaInSn). In this work, we first summarized the measuring methods that are suitable for determining this function and analysed their advantages and disadvantages. All of them disturb, to some degree, the melt flow, except for the Pressure Compensation Method (PCM); therefore, this method was used in the experiments. Closed TEFLON crucibles with a 60 mm length and 12.5 mm radius and Ga75wt%In25wt% alloy was used. The angular velocity (ω) was calculated from the compensation pressure measured at r = 5, 7.5, 10, and 12.5 mm in the 0–90 mT range of magnetic induction, B. Based on the ω(B, r) dataset, a suitable ω(B, r) function was determined for the simulation.

Electric Field Characteristics of Rotating Permanent Magnet Stimulation.

Neurostimulation devices that use rotating permanent magnets are being explored for their potential therapeutic benefits in patients with psychiatric and neurological disorders. This study aims to characterize the electric field (E-field) for ten configurations of rotating magnets using finite element analysis and phantom measurements. Various configurations were modeled, including single or multiple magnets, and bipolar or multipolar magnets, rotated at 10, 13.3, and 350 revolutions per second (rps). E-field strengths were also measured using a hollow sphere (r=9.2 cm) filled with a 0.9% sodium chloride solution and with a dipole probe. The E-field spatial distribution is determined by the magnets' dimensions, number of poles, direction of the magnetization, and axis of rotation, while the E-field strength is determined by the magnets' rotational frequency and magnetic field strength. The induced E-field strength on the surface of the head ranged between 0.0092 and 0.52 V/m. In the range of rotational frequencies applied, the induced E-field strengths were approximately an order or two of magnitude lower than those delivered by conventional transcranial magnetic stimulation. The impact of rotational frequency on E-field strength represents a confound in clinical trials that seek to tailor rotational frequency to individual neural oscillations. This factor could explain some of the variability observed in clinical trial outcomes.

Resonances of Supernova Neutrinos in Twisting Magnetic Fields.

We investigate the effect of resonant spin conversion of the neutrinos induced by the geometrical phase in a twisting magnetic field. We find that the geometrical phase originating from the rotation of the transverse magnetic field along the neutrino trajectory can trigger a resonant spin conversion of Dirac neutrinos inside the supernova, even if there were no such transitions in the fixed-direction field case. We have shown that, even though resonant spin conversion is too weak to affect solar neutrinos, it could have a remarkable consequence on supernova neutronization bursts where very intense magnetic fields are quite likely. We demonstrate how the flavor composition at Earth can be used as a probe to establish the presence of non-negligible magnetic moments, potentially down to 10^{-15}μ_{B} in upcoming neutrino experiments like the Deep Underground Neutrino Experiment and the Hyper-Kamiokande. Possible implications are analyzed.

Large Anomalous Hall Effect at Room Temperature in a Fermi‐Level‐Tuned Kagome Antiferromagnet

AbstractThe recent discoveries of surprisingly large anomalous Hall effect (AHE) in antiferromagnets have attracted much attention due to their promising use in spintronics devices. However, such AHE‐hosting antiferromagnetic materials are rare in nature. Herein, it is demonstrated that Mn2.4Ga, a Fermi‐level‐tuned kagome antiferromagnet, has a large anomalous Hall conductivity of ≈150 Ω−1 cm−1 at room temperature that surpasses the usual high values (i.e., 20–50 Ω−1 cm−1) observed so far in two outstanding kagome antiferromagnets, Mn3Sn and Mn3Ge. Although the triangular spin structure of Mn2.4Ga shows a weak net magnetic moment of ≈0.05 µB per formula unit, it guarantees a nonzero Berry curvature in the kagome plane. Moreover, the anomalous Hall conductivity exhibits a sign reversal with the rotation of a small magnetic field that can be ascribed to the field‐controlled chirality of the spin triangular structure. This theoretical calculations further suggest that the large AHE in Mn2.4Ga originates from a significantly enhanced Berry curvature associated with the tuning of the Fermi level close to the Weyl points. These properties, together with the ability to manipulate moment orientations using a moderate external magnetic field, make Mn2.4Ga extremely exciting for future antiferromagnetic spintronics.

Optoelectronic–thermomagnetic effect of a microelongated non-local rotating semiconductor heated by pulsed laser with varying thermal conductivity

Abstract In this study, we investigated the effect of a rotation field and magnetic field on a homogeneous photo-thermoelastic nonlocal material and how its thermal conductivity changes as a result of a linearly distributed thermal load. The thermal conductivity of an interior particle is supposed to increase linearly with temperature under the impact of laser pulses. Microelastic (microelements distribution), non-local semiconductors are used to model the problem under optoelectronic procedures, as proposed by the thermoelasticity theory. According to the microelement transport processes, the micropolar-photo-thermoelasticity theory accounts for the medium’s microelongation properties. This mathematical model is solved in two dimensions using the harmonic wave analysis. Non-local semiconductor surfaces can generate completely dimensionless displacement, temperature, microelongation, carrier density, and stress components with the appropriate boundary conditions. The effects of thermal conductivity, thermal relaxation times, magnetic pressure effect, laser pulses, and rotation parameters on wave propagation in silicon (Si) material are investigated and graphically displayed for a range of values.

Multifunctional Conductive and Electrogenic Hydrogel Repaired Spinal Cord Injury via Immunoregulation and Enhancement of Neuronal Differentiation.

Spinal cord injury (SCI) is a refractory neurological disorder. Due to the complex pathological processes, especially the secondary inflammatory cascade and the lack of intrinsic regenerative capacity, it is difficult to recover neurological function after SCI. Meanwhile, simulating the conductive microenvironment of the spinal cord reconstructs electrical neural signal transmission interrupted by SCI and facilitates neural repair. Therefore, a double-crosslinked conductive hydrogel (BP@Hydrogel) containing black phosphorus nanoplates (BP) is synthesized. When placed in a rotating magnetic field (RMF), the BP@Hydrogel can generate stable electrical signals and exhibit electrogenic characteristic. In vitro, the BP@Hydrogel shows satisfactory biocompatibility and can alleviate the activation of microglia. When placed in the RMF, it enhances the anti-inflammatory effects. Meanwhile, wireless electrical stimulation promotes the differentiation of neural stem cells (NSCs) into neurons, which is associated with the activation of the PI3K/AKT pathway. In vivo, the BP@Hydrogel is injectable and can elicit behavioral and electrophysiological recovery in complete transected SCI mice by alleviating the inflammation and facilitating endogenous NSCs to form functional neurons and synapses under the RMF. The present research develops a multifunctional conductive and electrogenic hydrogel for SCI repair by targeting multiple mechanisms including immunoregulation and enhancement of neuronal differentiation.

The Statistical Mechanics of Ideal Magnetohydrodynamic Turbulence and a Solution of the Dynamo Problem

We review and extend the theory of ideal, homogeneous, incompressible, magnetohydrodynamic (MHD) turbulence. The theory contains a solution to the ‘dynamo problem’, i.e., the problem of determining how a planetary or stellar body produces a global dipole magnetic field. We extend the theory to the case of ideal MHD turbulence with a mean magnetic field that is aligned with a rotation axis. The existing theory is also extended by developing the thermodynamics of ideal MHD turbulence based on entropy. A mathematical model is created by Fourier transforming the MHD equations and dynamical variables, resulting in a dynamical system consisting of the independent Fourier coefficients of the velocity and magnetic fields. This dynamical system has a large but finite-dimensional phase space in which the phase flow is divergenceless in the ideal case. There may be several constants of the motion, in addition to energy, which depend on the presence, or lack thereof, of a mean magnetic field or system rotation or both imposed on the magnetofluid; this leads to five different cases of MHD turbulence that must be considered. The constants of the motion (ideal invariants)—the most important being energy and magnetic helicity—are used to construct canonical probability densities and partition functions that enable ensemble predictions to be made. These predictions are compared with time averages from numerical simulations to test whether or not the system is ergodic. In the cases most pertinent to planets and stars, nonergodicity is observed at the largest length-scales and occurs when the components of the dipole field become quasi-stationary and dipole energy is directly proportional to magnetic helicity. This nonergodicity is evident in the thermodynamics, while dipole alignment with a rotation axis may be seen as the result of dynamical symmetry breaking, i.e., ‘broken ergodicity’. The relevance of ideal theoretical results to real (forced, dissipative) MHD turbulence is shown through numerical simulation. Again, an important result is a statistical solution of the ‘dynamo problem’.

Evidence for a Current System and Potential Structure in the Martian Magnetotail

AbstractWe present a case study of plasma and magnetic field observations in the Martian magnetotail using data from the Mars Atmosphere and Volatile EvolutioN (MAVEN) mission during an orbit when the spacecraft was in the optical shadow, past the dusk terminator and downstream of the strongest crustal magnetic fields. In this region, we observed multiple magnetic field rotations (a signature of currents) closely associated with energized (up to 100 eV) electron populations. Several transitions between closed and draped magnetic topologies also occur in this region, which are likely to be caused by magnetic reconnection between the interplanetary magnetic field (IMF) and crustal magnetic fields. We also observe two regions of energized, counter‐streaming electrons, which are rare in the magnetotail, but twice as likely to occur downstream of strong crustal magnetic fields when they are near the evening terminator. Together, the multiple magnetic field rotations, topological changes, and counter streaming electrons suggest the presence of an electric potential structure similar to those observed above the auroral arc regions at Earth.

Quantification and suppression of optical non-orthogonality and light intensity noise in all-optical hot atomic sensing systems

All-optical hot atomic sensing systems such as optical pumping magnetometers (OPM) and comagnetometers, nuclear magnetic resonance (NMR) magnetometers and gyroscopes, have the ability to sense magnetic field, anomalous field and inertial rotation, thus having a wide potential for applications in precision measurement, fundamental physics research and inertial navigation. System noise limits the minimum value of the signal that can be measured and there is coupling effect between the noises. Therefore, the quantification and suppression of various noise are challenging and should be investigated. As one of the major noises, the light intensity fluctuation of the probe light and the pump light affects the sensitivity of the all-optical hot atomic sensing systems. However, there has been no in-depth research on the quantification of the light intensity noise. In this paper, a method of measuring the light intensity noise is proposed, which can be applied to kinds of all-optical hot atomic sensing systems. For verification, the effects of probe and pump light intensity fluctuations on system noise are simulated and experimentally verified in a spin exchange relaxation free (SERF) comagnetometer. Besides, it is found that the optical non-orthogonality amplifies the probe light intensity noise by more than 3.4 times and a quantification method of optical non-orthogonality is proposed. Finally, a suppression method of the light intensity noise is presented by suppressing the optical non-orthogonality and the noise is suppressed by 59%. A universal light intensity noise quantification method is proposed for all-optical hot atomic sensing systems, and a light intensity noise suppression method is proposed for SERF comagnetometers, which can be applied to the suppression of noises coupled with atomic polarization.

The Influence of Graphene Oxide-Fe3O4 Differently Conjugated with 10-Hydroxycampthotecin and a Rotating Magnetic Field on Adenocarcinoma Cells.

Nanoparticles (e.g., graphene oxide, graphene oxide-Fe3O4 nanocomposite or hexagonal boron nitride) loaded with anti-cancer drugs and targeted at cancerous cells allowed researchers to determine the most effective in vitro conditions for anticancer treatment. For this reason, the main propose of the present study was to determine the effect of graphene oxide (GO) with iron oxide (Fe3O4) nanoparticles (GO-Fe3O4) covalently (c-GO-Fe3O4-HCPT) and non-covalently (nc-GO-Fe3O4-HCPT) conjugated with hydroxycamptothecin (HCPT) in the presence of a rotating magnetic field (RMF) on relative cell viability using the MCF-7 breast cancer cell line. The obtained GO-Fe3O4 nanocomposites demonstrated the uniform coverage of the graphene flakes with the nanospheres, with the thickness of the flakes estimated as ca. 1.2 nm. The XRD pattern of GO-Fe3O4 indicates that the crystal structure of the magnetite remained stable during the functionalization with HCPT that was confirmed with FTIR spectra. After 24 h, approx. 49% and 34% of the anti-cancer drug was released from nc-GO-Fe3O4-HCPT and c-GO-Fe3O4-HCPT, respectively. The stronger bonds in the c-GO-Fe3O4-HCPT resulted in a slower release of a smaller drug amount from the nanocomposite. The combined impact of the novel nanocomposites and a rotating magnetic field on MCF-7 cells was revealed and the efficiency of this novel approach has been confirmed. However, MCF-7 cells were more significantly affected by nc-GO-Fe3O4-HCPT. In the present study, it was found that the concentration of nc-GO-Fe3O4-HCPT and a RMF has the highest statistically significant influence on MCF-7 cell viability. The obtained novel nanocomposites and rotating magnetic field were found to affect the MCF-7 cells in a dose-dependent manner. The presented results may have potential clinical applications, but still, more in-depth analyses need to be performed.