In this paper, considering the effect of inertia ball, the static calculation model of angular contact ball bearings is established, the ball and the inner and outer raceway contact series parallel connection stiffness, deduced the formula of stiffness of the bearings, the use of FORTRAN language rotor-dynamics of the bearing calculation program, through the existing literature examples verify the correctness of the program. Combined with the actual turbo-pump rotor system of turbo-pump radial ball bearing radial bearing radial load stiffness is calculated, considering the additional influence of sealing fluid induced stiffness, at variable speed under the condition of calculation of bearing seal rotor system whirling frequency, the results accord with the actual engineering. In this paper, a multi factor simulation system for rotor-dynamics is developed, which provides a reference for design phase analysis of turbo-pump rotor-dynamics.