When converting a baffled stirred reactor to work with a different fluid, usually the original impeller must be replaced with a customized one. If the original impeller was designed for mixing liquids, its performance for liquid–solid suspensions may not be satisfactory. A case study is presented, where a two-blade original impeller is replaced with a new three-blade design. The new impeller shows clear improvements in mixing a liquid–solid suspension, while keeping the shaft power practically at the same level. As a result, a practically homogenous liquid–solid mixture is obtained, thus ensuring the required quality of the final product. The present numerical investigations employ the Eulerian multiphase model with renormalization (RNG) k–ε turbulence model to simulate the three-dimensional unsteady free-surface liquid–solid flow in a stirred tank. A sliding mesh approach was used to account for the impeller rotation within the expert code, FLUENT 16. The comparative quantitative analysis of the solid phase distribution and the relevant velocity profiles show that the new design of three-blade-impeller is significantly increasing the sedimentation time of the solid phase beyond the chemical reaction specific time. The necessary power to drive the new impeller has a slightly higher value than for the original impeller but it can be sustained by the existing driving system.