Introduction The emotional impact of patient loss in oncology and palliative care profoundly affects healthcare professionals. This study explores clinicians’ experiences, emotional reactions, and coping mechanisms in these fields, focusing on their professional and personal growth. It aims to provide a comprehensive understanding of how healthcare professionals from different regions and with varying years of experience deal with patient loss, emphasizing cultural, social, and institutional influences on their coping strategies. Methods A mixed-methods approach combined qualitative and quantitative elements. Data were collected using a Microsoft® Forms© survey targeting oncology and palliative care healthcare professionals. The survey included questions on experiences with patient loss, coping strategies, personal and professional growth, and beliefs. Statistical methods and thematic analysis were used to analyse quantitative and qualitative data. Ethical approval was obtained, and the survey ensured participant anonymity and confidentiality. Results The survey received 125 responses from nineteen countries. Emotional reactions to patient loss were significant, with various coping strategies reported, including spiritual practices, self-care, and professional support groups. Personal and professional growth were key outcomes of dealing with patient loss. Themes like Emotional Impact, Coping Mechanisms, and Reflections on Death and Dying were prevalent. Analysis revealed no significant correlation between the time taken by the participants to complete the survey and years of healthcare experience. Conclusion Healthcare professionals in oncology and palliative care face significant emotional challenges due to patient loss. The study emphasizes the importance of diverse and effective coping mechanisms, the supportive role of personal beliefs and workplace environments, and the journey of personal and professional growth amidst these challenges. It highlights the resilience of healthcare workers and underscores the need for supportive systems in managing the emotional aspects of patient care.
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